Light elements or compounds with an average atomic number () of less than 10 are difficult to detect due to their weak interactions with electrons and photons. Here, we introduce a direct thermal absorbance measurement platform for scanning electron microscopy. The technique, named ZEM, is particularly sensitive to low materials, including hydrogen ( = 1) and vacancy ( = 0).
View Article and Find Full Text PDFPurpose: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrotic lung disorder characterized by dry cough, fatigue, and exacerbated dyspnea. The prognosis of IPF is notably unfavorable, becoming extremely poor when the disease advances acutely. Effective therapeutic intervention is essential to mitigate disease progression; hence, early diagnosis and treatment are paramount.
View Article and Find Full Text PDFIntroduction: High use of psychotropic medications continues to be common in residential aged care homes despite the risk of harm and limited efficacy in people living with dementia. Research has shown that the organizational culture of aged care homes influences psychotropic medication use in residents with dementia. The Psychotropic medicines use in Residents And Culture: Influencing Clinical Excellence (PRACTICE) tool was developed to evaluate the organizational culture of aged care homes specific to the use of psychotropic medications.
View Article and Find Full Text PDFACS Appl Mater Interfaces
November 2024
The traditional sulfur selenization process in CuZnSn(S,Se) (CZTSSe) solar cell fabrication often results in the creation of localized anion vacancies ( and ). These vacancies are considered harmful defects as they can trap carriers generated by light, leading to reduced solar cell efficiency. Moreover, concrete evidence has been lacking on the extent of the impact caused by these anion vacancies.
View Article and Find Full Text PDFMetamaterial absorbers show great potential in many scientific and technological applications by virtue of their sub-wavelength and easy-to-adjust structure, with bandwidth as an important standard to measure the performance of the absorbers. In this study, our team designed a new broadband absorber, which consists of an indium arsenide (InAs) disk at the top, a zinc selenide (ZnSe)-chromium (Cr) stacked disk in the middle and a metal film at the bottom. Simulation results show that the absorber has remarkable absorptivity properties in the mid-long infrared band.
View Article and Find Full Text PDFCompared to other types of lung cancer, small cell lung cancer (SCLC) exhibits aggressive characteristics that promote drug resistance. Despite platinum-etoposide chemotherapy combined with immunotherapy being the current standard treatment, the rapid development of drug resistance has led to unsatisfactory clinical outcomes. This review focuses on the mechanisms contributing to the chemotherapy resistance phenotype in SCLC, such as increased intra-tumoral heterogeneity, alterations in the tumor microenvironment, changes in cellular metabolism, and dysregulation of apoptotic pathways.
View Article and Find Full Text PDFBackscattered electron (BSE) imaging based on scanning electron microscopy (SEM) has been widely used in scientific and industrial disciplines. However, achieving consistent standards and precise quantification in BSE images has proven to be a long-standing challenge. Previous methods incorporating dedicated calibration processes and Monte Carlo simulations have still posed practical limitations for widespread adoption.
View Article and Find Full Text PDFPurple sweet potato (PSP) powder with anthocyanins possesses the ability to reduce oxidative stress and inflammation. Studies have presumed a positive correlation between body fat and dry eye disease (DED) in adults. The regulation of oxidative stress and inflammation has been proposed as the mechanism underlying DED.
View Article and Find Full Text PDFObjectives: To compare the therapeutic effect of endoscopic-assisted lateral neck dissection and open lateral neck dissection in the treatment of lateral neck lymph node metastasis of patients with papillary thyroid carcinoma (PTC).
Methods: A retrospective analysis was carried out focusing on the general clinical data of 86 patients with PTC treated Baoding No.1 Central Hospital from January 2020 to September 2021.
Recent developments in nanoscale thermal metrology using electron microscopy have made impressive advancements in measuring either phononic or thermal transport properties of nanoscale samples. However, its potential in material analysis has never been considered. Here we introduce a direct thermal absorbance measurement platform in scanning electron microscope (SEM) and demonstrate that its signal can be utilized for atomic number () analysis at nanoscales.
View Article and Find Full Text PDFThe identification of ancient wool is of great significance in archaeology; however, conventional methods are unwieldy or even ineffective when testing contaminated or severely degraded ancient samples. Therefore, it is highly desirable to develop an ultrasensitive detection method for ancient wool. In this study, an ultrasensitive electrochemical immunosensor is proposed and developed to detect ancient wool, where graphene oxide (GO), aldehyde-functionalized ionic liquid (AFIL) composites and gold nanoparticles (AuNPs) are synthesized as efficient signal amplifiers.
View Article and Find Full Text PDFHeterogeneous catalysis based on air-stable lanthanide complexes is relatively rare, especially for electrochemical water oxidation and reduction. Therefore, it is highly desired to investigate the synergy caused by cocatalysts on the lanthanide complex family for heterogeneous catalysis because of their structural diversity, air/moisture insensitivity, and easy preparation under an air atmosphere. Two mononuclear and three dinuclear dysprosium complexes containing a series of Schiff-base ligands have been demonstrated as robust electrocatalysts for triggering heterogeneous water oxidation in alkaline solution, in which the complex [Dy(hmb)(OAc)]·MeCN() was revealed to have the best activity toward heterogeneous water oxidation among all five complexes in the present study.
View Article and Find Full Text PDFThe Maritime Silk Road was the major trade route between eastern and western civilizations in the Middle Ages. However, hardly any silk products have been found along the transoceanic trade route. Thus, the extrasensitive detection of silk relic traces has tremendous importance in research regarding the Maritime Silk Road.
View Article and Find Full Text PDFIn recent years, increasing attention has been paid to the origin, transmission and communication of silk. However, this is still an unsolved mystery in archaeology. The identification of silk-producing species, especially silk produced by Bombyx mori (B.
View Article and Find Full Text PDFThe multifunctional hard X-ray nanoprobe at Taiwan Photon Source (TPS) exhibits the excellent ability to simultaneously characterize the X-ray absorption, X-ray excited optical luminescence (XEOL) as well as the dynamics of XEOL of materials. Combining the scanning electron microscope (SEM) into the TPS 23A end-station, we can easily and quickly measure the optical properties to map out the morphology of a ZnO microrod. A special phenomenon has been observed that the oscillations in the XEOL associated with the confinement of the optical photons in the single ZnO microrod shows dramatical increase while the X-ray excitation energy is set across the Zn K-edge.
View Article and Find Full Text PDFSpecies identification is of key significance for exploring the origin and transmission of ancient silks. In this study, two novel methods, i.e.
View Article and Find Full Text PDFThe identification of ancient wool is of great importance in archaeology. Despite lots of meaningful information can be achieved by conventional detection methods, that is, light and electron microscopy, spectroscopy, and chromatography, the efficacy is likely to be limited in the detection of ancient samples with contamination or severe degradation. In this work, an immunoassay was proposed and performed for the identification of ancient wool.
View Article and Find Full Text PDFPolarization-dependent hard X-ray excited optical luminescence (XEOL) was used to study not only the optical properties but also the crystallographic orientations of a non-polar a-plane ZnO wafer. In addition to a positive-edge jump and extra oscillations in the near-band-edge (NBE) XEOL yield, we observed a blue shift of the NBE emission peak that follows the polarization-dependent X-ray absorption near-edge structure (XANES) as the X-ray energy is tuned across the Zn K-edge. This NBE blue shift is caused by the larger X-ray absorption, generating higher free carriers to reduce the exciton-LO phonon coupling, which causes a decrease in the exciton activation energy.
View Article and Find Full Text PDFThe formation of haloacetamides (HAcAms) and haloacetonitriles (HANs) from a solution containing natural organic matter and a secondary effluent sample was evaluated for disinfection by chlorination, chloramination, and chlorination followed by chloramination (ClNHCl process). The use of preformed monochloramine (NHCl) produced higher concentrations of HAcAms and lower concentrations of HANs than chlorination, while the ClNHCl process produced the highest concentrations of HAcAms and HANs. These results indicate that the ClNHCl process, which inhibited the formation of regulated trihalomethanes compared with chlorination, enhanced the formation of HAcAms and HANs.
View Article and Find Full Text PDFPien Tze Huang (PZH) is a well-known traditional Chinese formulation and has long been used as an alternative remedy for cancers in China and Southeast Asia. Recently, antitumor activity of PZH on several tumors have been increasingly reported, but its antitumor activity and the possible action mechanism on osteosarcoma remains unclear. After treatment with PZH, cell viability of MG-63 cells was dose-dependently inhibited compared to control cells.
View Article and Find Full Text PDFAtomic force microscope (AFM) is a powerful tool for force measurement in nanoscale. Many methods have been developed to obtain the precise cantilever's spring constant for improving the accuracy of force measurement. AFM cantilevers are usually made by single crystal silicon of which the anisotropic material property seriously affects the spring constant of cantilevers and has not considered before.
View Article and Find Full Text PDFAtomic force microscopy (AFM) can be used to measure the surface morphologies and the mechanical properties of nanostructures. The force acting on the AFM cantilever can be obtained by multiplying the spring constant of AFM cantilever and the corresponding deformation. To improve the accuracy of force experiments, the spring constant of AFM cantilever must be calibrated carefully.
View Article and Find Full Text PDFAtomic force microscopy (AFM) probe with different functions can be used to measure the bonding force between atoms or molecules. In order to have accurate results, AFM cantilevers must be calibrated precisely before use. The AFM cantilever's spring constant is usually provided by the manufacturer, and it is calculated from simple equations or some other calibration methods.
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