Aggregation-Induced Emission Carbon Dot-Based Multicolor Circularly Polarized Afterglow with a High Luminescence Dissymmetry Factor.

Carbon dots (CDs) with circularly polarized afterglow (CPA) materials have drawn increasing attention as cutting-edge research in the field of chiral luminescence owing to their promising applications in various fields. However, due to the weak optical activity of chiral CDs and the limited afterglow color of phosphorescent CDs, it is still a formidable challenge to construct multicolor CD-based CPA materials with a high luminescence dissymmetry factor (). Herein, positively charged aggregation-induced emission (AIE) CDs were prepared using dithiosalicylic acid and ionic liquid as precursors.

Analysis of Sex-Specific Gene-by-Cohort and Genetic Correlation-by-Cohort Interaction in Educational and Reproductive Outcomes Using the UK Biobank Data.

Synthesizing prior gene-by-cohort (G×C) interaction studies, we theorize that changes in genetic effects by social conditions depend on the level of resource constraints, the distribution and use of resources, structural constraints, and constraints on individual choice. Motivated by the theory, we explored several sex-specific G×C trends across a set of outcomes using 30 birth cohorts of UK Biobank data (N = 400,000). We find that genetic coefficients on years of schooling and secondary educational attainment substantially decrease, but genetic coefficients on college attainments only moderately increase.

Meat systems produced with Monascus pigment water-in-oil-in-water multiple emulsion as pork fat replacers.

Multiple emulsions have drawn great attentions from researchers in the production of low-fat foods. The Monascus pigment W/O/W multiple emulsions were prepared by a two-step emulsification procedure with Monascus pigment as inner water phase, flaxseed gum (FG) as internal water phase gel, soybean oil as oil phase, and pea protein isolate (PPI) as outer water phase. We aimed to investigate the quality of pork emulsion systems in which pork fat was replaced by W/O/W emulsions.

A quantile integral linear model to quantify genetic effects on phenotypic variability.

Detecting genetic variants associated with the variance of complex traits, that is, variance quantitative trait loci (vQTLs), can provide crucial insights into the interplay between genes and environments and how they jointly shape human phenotypes in the population. We propose a quantile integral linear model (QUAIL) to estimate genetic effects on trait variability. Through extensive simulations and analyses of real data, we demonstrate that QUAIL provides computationally efficient and statistically powerful vQTL mapping that is robust to non-Gaussian phenotypes and confounding effects on phenotypic variability.

Gene-by-peer-environment interaction effects on cigarette, alcohol, and marijuana use among US high school students of European Ancestry.

Research has shown that adolescents' substance use behavior is determined not only by individual characteristics but also by peer environments, and an emerging literature in social genomics has also found that individual genotypes moderate peer effects on egos' substance use. However, the previous literature on genetic by peer environment (GxPE) interaction effects is limited by the use of genetic measures with limited power and a lack of focus on causality. Based on a sample of about 4000 adolescents of European Ancestry from the National Longitudinal Study of Adolescent to Adult Health, this study utilizes polygenic scores to examine GxPE interactions between ego's genetics and peers' cigarette, alcohol, and marijuana use.

The Stability, Microstructure, and Microrheological Properties of Pigment Double Emulsions Stabilized by Polyglycerol Polyricinoleate and Soybean Protein Isolate.

pigment is a natural food pigment and is commonly used for coloring and as antiseptic of cured meat products, confectionery, cakes, and beverages. However, pigment is sensitive to environmental conditions. The main aim of this study was to investigate the effect of polyglycerol polyricinoleate (PGPR) and soy protein isolate (SPI) on the particle size, zeta potential, physical stability, microstructure, and microrheological properties of pigment double emulsions.

Uncertainty in Continuous Scatterplots, Continuous Parallel Coordinates, and Fibers.

In this paper, we introduce uncertainty to continuous scatterplots and continuous parallel coordinates. We derive respective models, validate them with sampling-based brute-force schemes, and present acceleration strategies for their computation. At the same time, we show that our approach lends itself as well for introducing uncertainty into the definition of fibers in bivariate data.

Cognitive limitations in older adults receiving care reduces well-being among spouse caregivers.

A large number of older adults have physical and/or cognitive challenges and require help to manage everyday activities. Many older adults receive care from a spouse. Over the long term, this has adverse consequences for caregiver health and well-being.