Microsporidian Nosema bombycis hijacks host vitellogenin and restructures ovariole cells for transovarial transmission.

Microsporidia are a group of obligate intracellular parasites that infect almost all animals, causing serious human diseases and major economic losses to the farming industry. Nosema bombycis is a typical microsporidium that infects multiple lepidopteran insects via fecal-oral and transovarial transmission (TOT); however, the underlying TOT processes and mechanisms remain unknown. Here, we characterized the TOT process and identified key factors enabling N.

The First Report on the Transovarial Transmission of Microsporidian in Lepidopteran Crop Pests and .

Microsporidia are ubiquitous fungi-related parasites infecting nearly all vertebrates and invertebrates. Microsporidian is a natural pathogen of multiple insects, including the silkworm and many agricultural and forest pests. can transovarially transmit in silkworm and cause huge economic losses to the sericulture.