Publications by authors named "Boyan K Tsankov"
It has long been appreciated that cues from the innate immune system orchestrate downstream adaptive immune responses. Although previous work has focused on the roles of Toll-like receptors in this regard, relatively little is known about how Nod-like receptors instruct adaptive immunity. Here we review the functions of different members of the Nod-like receptor family in orchestrating effector and anamnestic adaptive immune responses.
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- A systematic review and meta-analysis were conducted to assess how comorbidities affect COVID-19 severity in children, revealing limited information on this topic.
- The analysis included 42 studies encompassing over 275,000 children without comorbidities and about 9,400 with comorbidities, finding that severe COVID-19 occurred significantly more often in children with underlying health issues (5.1% vs. 0.2%).
- The results indicated a higher risk of severe cases and COVID-19-related deaths for children with comorbidities, specifically highlighting obesity as a notable risk factor.