Modeling the effects of prebiotic interventions on luminal and mucosa-associated gut microbiota without and with challenge .

Prebiotics can modulate the gut microbial community composition and function for improved (gut) health and increase resilience against infections. models of the gut facilitate the study of intervention effects on the gut microbial community relevant to health. The mucosa-associated gut microbiota, which thrives in close contact with the host plays a pivotal role in colonization resistance and health.