Publications by authors named "Bowen Wen"

Nanosized activated carbon (NAC) as emerging engineered nanomaterials may interact with nanoplastics prevalent in aquatic environments to affect their fate and transport. This study investigated the effects of particle property (charge and concentration), water chemistry [electrolytes, pH, humic acid (HA), and sodium alginate (SA)], and hydrodynamic condition [wave (i.e.

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Background: Laccase (LAC) gene family plays a pivotal role in plant lignin biosynthesis and adaptation to various stresses. Limited research has been conducted on laccase genes in common beans.

Results: 29 LAC gene family members were identified within the common bean genome, distributed unevenly in 9 chromosomes.

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Glutathione plays a critical role in plant growth, development and response to stress. It is a major cellular antioxidant and is involved in the detoxification of xenobiotics in many organisms, including plants. However, the role of glutathione-dependent redox homeostasis and associated molecular mechanisms regulating the antioxidant system and pesticide metabolism remains unclear.

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Due to the unique physicochemical properties, mesoporous silica nanoparticles (MONs) have been widely utilized in biomedical fields for drug delivery, gene therapy, disease diagnosis and imaging. With the extensive applications and large-scale production of MONs, the potential effects of MONs on human health are gaining increased attention. To better understand the cellular and molecular mechanisms underlying the effects of MONs on the mouse liver, we profiled the transcriptome of 63,783 single cells from mouse livers following weekly intravenous administration of MONs for 2 weeks.

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Article Synopsis
  • * FHCS is made from Pluronic F-127 combined with carboxymethyl chitosan/sodium alginate nanoparticles and nanohydroxyapatite, and has shown non-toxicity and good compatibility with blood.
  • * In animal tests, the FHCS-5 variant (with 5 mg/mL nCS) effectively promoted bone regeneration in critical-size bone defects, enhancing the expression of osteogenic genes and proteins, and leading to new bone formation confirmed by imaging and staining techniques.
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