Comparison of MUSE-DWI and conventional DWI in the application of invasive breast cancer and malignancy grade prediction: A comparative study.

Objective: To compare MUSE-DWI with conventional DWI in assessing lesions of invasive breast cancer and evaluating the ADC values for preoperative histological grading.

Methods: A retrospective analysis was conducted on 63 lesions confirmed as invasive breast cancer by surgical or biopsy pathology. Preoperatively, all patients underwent MUSE-DWI, conventional DWI, and dynamic contrast-enhanced (DCE) scans.

Gold-Catalyzed Precise Bromination of Polystyrene.

Modification of commodity aromatic polymers is highly desirable for accessing materials with new properties. The long-standing challenge for such approaches lies in the development of catalytic methods that can functionalize the aromatic polymers with high precision while preserving the molecular weight and distribution of the starting polymers without any alteration. Herein, we report a highly efficient AuCl-catalyzed site-selective aromatic C-H halogenation of polystyrene.

The impact of starchy food structure on postprandial glycemic response and appetite: a systematic review with meta-analysis of randomized crossover trials.

Background: Starchy foods can have a profound effect on metabolism. The structural properties of starchy foods can affect their digestibility and postprandial metabolic responses, which in the long term may be associated with the risk of type 2 diabetes and obesity.

Objectives: This systematic review sought to evaluate the clinical evidence regarding the impact of the microstructures within starchy foods on postprandial glucose and insulin responses alongside appetite regulation.

Generation of α-Boryl Radicals and Their Conjugate Addition to Enones: Transition-Metal-Free Alkylation of gem-Diborylalkanes.

A transition-metal-free method for the alkylation of gem-diborylalkanes with α,β-unsaturated ketones has been developed. It is demonstrated that the α-boryl radicals can be generated efficiently from gem-diborylalkanes with the aid of catechol and oxidants. The α-boryl radicals formed through such process can be engaged in conjugate addition reaction with α,β-unsaturated ketones.

Ring-opening iodination and bromination of unstrained cycloalkanols through β-scission of alkoxy radicals.

Ring-opening iodination or bromination of unstrained cycloalkanols with NaI or NaBr and PhI(OAc) under visible light irradiation is developed. In this protocol the concentration of I is modulated through the generation of triiodide (I), thus significantly avoiding undesired side reactions. The reaction is under mild conditions and has a wide substrate scope, thus providing a practically useful method for accessing ω-iodo or ω-bromoketones.

Visible-light-mediated C2-amination of thiophenes by using DDQ as an organophotocatalyst.

In this work, a direct C-H activation of thiophenes was presented via an oxidation pathway under visible-light irradiation, in which the thiophene radical cation serves as the key intermediate. Various thiophenes and azoles could be transformed into the corresponding amination products well, and HO was the only byproduct which is environmentally benign. Our results showed that tert-butyl nitrite (TBN) served as the electron transfer mediator and O as the terminal oxidant to regenerate the photocatalyst DDQ and revive the photocatalytic cycle.

Photocatalytic Dehydrogenative Cross-Coupling of Alkenes with Alcohols or Azoles without External Oxidant.

Direct cross-coupling between alkenes/R-H or alkenes/RXH is a dream reaction, especially without external oxidants. Inputting energy by photocatalysis and employing a cobalt catalyst as a two-electron acceptor, a direct C-H/X-H cross-coupling with H evolution has been achieved for C-O and C-N bond formation. A new radical alkenylation using alkene as the redox compound is presented.