Identification of novel antioxidant collagen peptides for preventing and treating H O -induced oxidative stress in HepG2 cells through in vitro and in silico approaches.

Background: Nowadays, the prevalence of oxidative stress-related chronic diseases is increasing. The identification of novel antioxidant collagen peptides to counteract oxidative stress for individuals' health has gained significant attention.

Results: In this study, collagen peptides with antioxidant activities were separated and identified by ion chromatography, reversed-phase high-performance liquid chromatography and liquid chromatography-tandem mass spectrometry.

Functions and applications of emerging metal-organic-framework liquids and glasses.

Traditional metal-organic-frameworks (MOFs) have been extensively studied and applied in various fields across chemistry, biology and engineering in the past decades. Recently, a family of emerging MOF liquids and glasses have gained ever-growing research interests owing to their fascinating phase transitions and unique functions. To date, a growing number of MOF crystals have been found to be capable of transforming into liquid and glassy states under external stimuli, which overcomes the limitations of MOF crystals by introducing functional disorder in a controlled manner and offering some desirable properties.

Trivalent Cations Detection of Magnetic-Sensitive Microcapsules by Controlled-Release Fluorescence Off-On Sensor.

A pyrene-based derivative, 2-((pyrene-1-ylmethylene)amino)ethanol (PE) nanoparticle, was encapsulated via water-in-oil-in-water (W/O/W) double emulsion with the solvent evaporation method by one-pot reaction and utilized as a fluorescence turn-on sensor for detecting Fe, Cr, and Al ions. Magnetic nanoparticles (MNPs) embedded in polycaprolactone (PCL) were used as the magnetic-sensitive polyelectrolyte microcapsule-triggered elements in the construction of the polymer matrix. The microcapsules were characterized by ultraviolet-visible (UV-Vis) and photoluminescence (PL) titrations, quantum yield (Φ) calculations, H nuclear magnetic resonance (NMR), scanning electron microscopy (SEM), and superconducting quantum interference device magnetometry (SQUID) studies.

The Multifunctionally Graded System for a Controlled Size Effect on Iron Oxide-Gold Based Core-Shell Nanoparticles.

We report that FeO@Au core-shell nanoparticles (NPs) serve as a multifunctional molecule delivery platform. This platform is also suitable for sensing the doxorubicin (DOX) through DNA hybridization, and the amount of carried DOX molecules was determined by size-dependent FeO@Au NPs. The limits of detection (LODs) for DOX was found to be 1.

Antioxidant cuttlefish collagen hydrolysate against ethyl carbamate-induced oxidative damage.

Ethyl carbamate (EC) has been associated with the generation of reactive oxygen species (ROS) and depletion of glutathione (GSH), leading to a decline in cell viability. In this study, we found that the cuttlefish collagen hydrolysate (CCH) exhibited high antioxidant activity in scavenging hydroxyl radicals (IC = 0.697 mg mL), which was also effective in combating EC-induced oxidative damage in liver hepatocellular carcinoma HepG2 cells.

Isolation and identification of an antioxidant collagen peptide from skipjack tuna () bone.

To date, many researchers have developed active components that are derived from seafood processing for the purposes of healthcare. Here, an antioxidant collagen peptide was obtained from skipjack tuna () bone by using a combination of trypsin and chymotrypsin as the catalyst. The amino acid sequence of the peptide was identified as Ser-Ser-Gly-Pro-Pro-Val-Pro-Gly-Pro-Met-Gly-Pro-Met-Gly-Pro-Arg (SSGPPVPGPMGPMGPR) by liquid chromatography-electrospray ionization quadrupole time-of-flight mass spectrometry (LC-ESI-QTOF-MS) analysis.

Eco-Friendly and Biodegradable Biopolymer Chitosan/Y₂O₃ Composite Materials in Flexible Organic Thin-Film Transistors.

The waste from semiconductor manufacturing processes causes serious pollution to the environment. In this work, a non-toxic material was developed under room temperature conditions for the fabrication of green electronics. Flexible organic thin-film transistors (OTFTs) on plastic substrates are increasingly in demand due to their high visible transmission and small size for use as displays and wearable devices.