Publications by authors named "Bouzid D"
Article Synopsis
- - The study investigates the effectiveness of Objective Structured Clinical Examinations (OSCEs) for evaluating medical students, revealing that while in-person assessments provide depth, they also lead to inconsistencies due to varying examiner standards.
- - Data from 900 medical students at Université Paris Cité was analyzed over multiple OSCE sessions, showing significant differences in scores based on staff who graded them, highlighting the need for a statistical method to account for this variability.
- - The results indicate that both staff and student variances affect OSCE scores, with staff variability being notably impactful; implementing two raters for consensus grading can help enhance score reliability.
Purpose: The efficacy of the 1-h bundle for emergency department (ED) patients with suspected sepsis, which includes lactate measurement, blood culture, broad-spectrum antibiotics administration, administration of 30 mL/kg crystalloid fluid for hypotension or lactate ≥ 4 mmol/L, remains controversial.
Methods: We carried out a pragmatic stepped-wedge cluster-randomized trial in 23 EDs in France and Spain. Adult patients with Sepsis-3 criteria or a quick sequential organ failure assessment (SOFA) score ≥ 2 or a lactate > 2 mmol/L were eligible.
Introduction: Machine learning (ML) is increasingly being used to predict antimicrobial resistance (AMR). This review aims to provide physicians with an overview of the literature on ML as a means of AMR prediction.
Methods: References for this review were identified through searches of MEDLINE/PubMed, EMBASE, Google Scholar, ACM Digital Library, and IEEE Xplore Digital Library up to December 2023.
Article Synopsis
- Respiratory syncytial virus (RSV) causes serious lower respiratory infections in young children and the elderly.
- Monoclonal antibodies like palivizumab and nirsevimab help prevent bronchiolitis in these at-risk groups.
- Four types of vaccines are in development, including subunit, mRNA, recombinant vector, and live attenuated vaccines, aimed at protecting pregnant women’s infants and older adults with health issues.
Article Synopsis
- The study aimed to evaluate the effectiveness of the Consultation And Relational Empathy (CARE) measure for assessing medical students' empathy during Objective and Structured Clinical Examinations (OSCEs), addressing the lack of a definitive tool for this purpose.
- Researchers analyzed the CARE measure's psychometric properties and compared scores given by examiners and standardized patients (SPs) to 129 students, finding discrepancies in their evaluations.
- Although the CARE measure had satisfactory overall properties, the inter-rater reliability was deemed poor, suggesting that the evaluators and the type of SP significantly impact the assessment of empathy in medical education.
Article Synopsis
- The study investigates the effectiveness of Extended Focused Assessment with Sonography in Trauma (eFAST) for patients with stab wounds to the chest or abdomen, comparing it to CT scans.
- Out of 200 patients, eFAST was particularly valuable in identifying urgent conditions like cardiac tamponade and haemothorax, with high sensitivity and specificity for these injuries.
- However, eFAST showed lower sensitivity for diagnosing pneumothorax and haemoperitoneum, indicating a need for further research across multiple centers to validate these findings.
Article Synopsis
- Respiratory syncytial virus (RSV) significantly impacts respiratory health in older adults and those with risk factors, leading to increased interest in detecting and managing the virus effectively.!* -
- The review aims to provide healthcare professionals with updated insights into RSV's prevalence, recent clinical trials on vaccines, and information about current and developing treatments.!* -
- As the understanding of RSV in adults improves, new preventive and therapeutic approaches are emerging to better address this public health concern.!*
Article Synopsis
- The study aimed to evaluate the effectiveness of self-administered low-dose methoxyflurane on managing trauma pain in patients outside the emergency department during the COVID-19 pandemic at Bichat University Medical Center in Paris.
- It involved two groups: a control group receiving standard pain management and an intervention group using methoxyflurane alongside standard treatments.
- Results showed both groups reported lower pain levels over time, with the intervention group experiencing a greater reduction between specific time points, indicating methoxyflurane may enhance pain relief in similar patients.
Article Synopsis
- Objective structured clinical examinations (OSCE) help assess medical students' skills, and this study evaluated third-year students' roles as standardized patients in these exams.
- In a pilot session, their OSCE scores were compared with third-year students who did not participate, revealing that those involved had significantly better scores (17 vs. 14.5 out of 20).
- Most participating students felt that being standardized patients reduced their stress, enhanced their preparedness, and improved their communication skills, indicating the potential for broader implementation of this approach in medical education.
Article Synopsis
- The study evaluated the effectiveness of nasopharyngeal swabs compared to bronchoalveolar lavage (BAL) for detecting non-SARS-CoV-2 respiratory viruses in pneumonia patients during a retrospective analysis from 2012 to 2018 at a French hospital.
- In a cohort of 276 patients, primary findings showed that nasopharyngeal swabs detected viruses in 34.4% of cases, while BAL detected them in 29.0%, revealing an overall agreement of 83.7% between the two methods.
- The research concluded that while both testing methods are reliable, BAL may still be beneficial when nasopharyngeal swabs return negative results, especially for certain viruses like rhinovirus
Background: Objective structured clinical examinations (OSCEs) are known to be a fair evaluation method. These recent years, the use of online OSCEs (eOSCEs) has spread. This study aimed to compare remote versus live evaluation and assess the factors associated with score variability during eOSCEs.
View Article and Find Full Text PDFMonoclonal antibodies (MAbs) targeting the Spike glycoprotein of SARS-CoV-2 is a key strategy to prevent severe COVID-19. Here, the efficacy of two monoclonal antibody bitherapies against SARS-CoV-2 was assessed on 92 patients at high risk of severe COVID-19 between March and October 2021 (Bichat-Claude Bernard Hospital, Paris, France). Nine patients died despite appropriate management.
View Article and Find Full Text PDFIntroduction: The maximum gain in quality of life after lung transplantation (LT) is expected between six months and one year after LT, as the occurrence of chronic lung allograft dysfunction may mask the beneficial effects beyond one year. Thus, the postoperative period could be the cornerstone of graft success. We sought to describe the factors present before postoperative admission to the ICU and associated with favorable, arduous or fatal pathway within 90 days of LT.
View Article and Find Full Text PDFArticle Synopsis
- * A study in an ICU involving 219 septic patients showed that 15% had sepsis-associated liver dysfunction, which was associated with lower HDL levels.
- * Despite the lower HDL-C concentrations in patients with liver dysfunction, no overall relationship was found between lipoprotein levels and liver dysfunction markers affecting outcomes.
Unlabelled: The COVID-19 pandemic has led health schools to cancel many on-site training and exams. Teachers were looking for the best option to carry out online OSCEs, and Zoom was the obvious choice since many schools have used it to pursue education purposes.
Methods: We conducted a feasibility study during the 2020-2021 college year divided into six pilot phases and the large-scale eOSCEs on Zoom on June 30th, 2021.
Article Synopsis
- The COVID-19 pandemic caused significant challenges for emergency departments (EDs), necessitating quick adaptations in their operations.
- A study focused on 5 academic EDs in a hard-hit region of France explored how they identified suspected COVID-19 cases and implemented a triage system based on real-time infection rates.
- The findings highlight hospitals' ability to reorganize and effectively manage resources during the crisis, providing insights that could help other EDs facing similar situations in the future.
Article Synopsis
- - The study analyzed rhinovirus infections in 178 hospitalized patients in Paris over several months, focusing on their clinical presentations and outcomes.
- - Key findings showed that a majority of patients had chronic respiratory conditions or were immunosuppressed, with different types of rhinoviruses (HRV-A, -B, and -C) showing varying associations with complications like pneumonia and ICU admissions.
- - Understanding the molecular differences between rhinovirus types is essential for developing targeted treatments to improve health outcomes in at-risk patients.
Article Synopsis
- The study aimed to validate the safety of a combined diagnostic strategy for ruling out pulmonary embolism (PE) that incorporates the YEARS rule and age-adjusted D-dimer thresholds in emergency departments across France and Spain.
- It involved a total of 1414 patients who were either at low risk for PE or had an intermediate risk, examining the outcomes of using different intervention strategies regarding chest imaging and D-dimer levels.
- The results showed that the intervention group had a very low rate of venous thromboembolism at 3 months (0.15%), suggesting that this combined strategy is a safe alternative for excluding PE without unnecessary imaging.
Introduction: Radiotherapy (RT) for head and neck cancer is now guided by cone-beam computed tomography (CBCT). We aim to identify a CBCT radiomic signature predictive of progression to RT.
Material And Methods: A cohort of 93 patients was split into training ( = 60) and testing ( = 33) sets.
Article Synopsis
- Quantitative PCR cycle threshold (Ct) values indicate the number of amplification cycles needed for a positive result and can reflect the quantity of pathogens in gastrointestinal infections, but their clinical relevance is uncertain.
- This systematic review analyzed literature to determine the relationship between Ct values of gastrointestinal pathogens and patient symptoms and outcomes, focusing on adult and pediatric populations.
- Out of 33 studies, some demonstrated significant links between low Ct values and increased symptom severity or mortality, particularly with norovirus and rotavirus, while others showed no clear association for symptom duration or hospital stay lengths; further large-scale research is needed.