Dioxins, PFOS, and 20 other Persistent Organic Pollutants in Eggs of Nine Wild Bird Species from the Vaal River, South Africa.

The Vaal River catchment drains the largest and most populated industrial and mining region in Southern Africa. Heron, ibis, cormorant, egrets, and darter eggs, representing three habitats and four feeding guilds, were collected at four locations in 2009/10 to identify hotspots and hazards associated with persistent organic pollutants (POPs). The POPs included 21 organochlorine pesticides, five polybrominated diphenyl ether (PBDE) classes, 18 polychlorinated biphenyls (PCBs including six non-dioxin-like PCBs; NDL-PCB), and 12 dioxin-like PCBs (DL-PCBs), 17 polychlorinated dibenzo-p-dioxins and dibenzo-p-furans (PCDD/Fs), and perfluorooctane sulfonate (PFOS).

The efficacy and safety of eculizumab in patients and the role of C5 polymorphisms.

Eculizumab is an orphan drug with indications for extremely rare autoimmune disorders. It is primarily prescribed for use in patients with paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome; but is also highly effective in the treatment of myasthenia gravis, among others. By binding to the C5 protein in the complement system, eculizumab effectively inhibits cellular hemolysis and autoimmune reactions.

Microplastics in the Indian and South Atlantic oceans translocate to gills, digestive glands, and muscle of the chokka squid Loligo reynaudii.

Comparative microplastic (MP) data for cephalopods between oceans is scarce. Our aim was to quantify, characterise, and compare MPs in gills, digestive gland, and mantle of chokka squid from the South Atlantic Ocean (SAO) and Indian Ocean (IO) off the coast of South Africa. South African squid had more MPs compared with other studies (means = 2.

Spatial trends and ecotoxic risk assessment of selected pharmaceuticals in sediments from Lake Victoria, Uganda, East Africa.

Pharmaceutical residues in the aquatic environment are an emerging issue of global concern because of their effects on ecosystems including; antibacterial resistance development and endocrine disruption. Lake Victoria is the largest freshwater lake in Africa, and the second largest lake in the world. It is also the main source of the White Nile River, arguably the longest river in the world, flowing through South Sudan, Sudan, Ethiopia and Egypt, discharging into the Mediterranean Sea.

Elements in muscle tissue of three dolphin species from the east coast of South Africa.

We investigated elemental concentrations in muscle tissue of three species of dolphins incidentally bycaught off the KwaZulu-Natal coastline, South Africa. Thirty-six major, minor and trace elements were analysed in Indian Ocean humpback dolphin Sousa plumbea (n = 36), Indo-Pacific bottlenose dolphin Tursiops aduncus (n = 32) and the Common dolphin Delphinus delphis (n = 8). Significant differences in concentration between the three species were observed for 11 elements (cadmium, iron, manganese, sodium, platinum, antimony, selenium, strontium, uranium, vanadium and zinc).

HIV-antiretrovirals in river water from Gauteng, South Africa: Mixed messages of wastewater inflows as source.

South Africa has the highest number of people living with the human immunodeficiency virus (HIV). High usage of HIV-antiretroviral drugs (ARVs) for the treatment of the acquired immunodeficiency syndrome (AIDS) leads to the presence of ARVs in the environment. Wastewater is a major contributor of pharmaceuticals in surface and drinking water as wastewater treatment plants (WWTPs) are not designed to remove these compounds.

Ten Bird Species, Six Guilds, Three Habitats, and 59 Chlorinated and Brominated POPs: What do 64 Eggs from the Largest Economic Hub of Southern Africa tell us?

There is little information on how POPs in eggs of different terrestrial, wetland, and aquatic birds share a large urban and rural landscape relate. We collected and analysed 64 eggs belonging to ten species of six feeding guilds, and compared organic chlorinated pesticide (OCP), polychlorinated biphenyl (PCB), and brominated flame retardants (BFR) residue concentrations and compositions. The eggs were collected in the Gauteng and the northern part of the Free Sate provinces of South Africa, one of the largest economic hubs in Africa.

The Wasp as a Terrestrial Indicator of Environmental Metal Composition: Evidence from Zimbabwe.

We explored metal concentrations in wasps from 4 sites near Harare, Zimbabwe, on a 106 km west-east transect. We found elevated concentrations at 2 presumed-polluted sites (a platinum [Pt] mine and a known polluted lake) located near a metal-enriched geological feature (the Great Dyke). A site in urban Harare and a nature reserve served as reference.

Persistent organic pollutants in sea bird eggs from the Indian Ocean's Mascarene Basin.

We report the concentrations of persistent organic pollutants (POPs) in seabird eggs from St. Brandon's Atoll, a tropical island system in the western Indian Ocean. Ten eggs each of sooty terns (Onychoprion fuscatus), fairy terns (Gygis alba), and common noddies (Anous stolidus) were collected from the atoll.

Chlorinated and brominated persistent compounds in hard coral, soft coral, and parrotfish from remote Mascarene islands.

Persistent halogenated compounds (PHC) are of concern for human and environmental health. Persistent Organic Pollutants (POPs) are regulated by international treaties, but alternative compounds such as novel brominated flame retardants (NBFRs) and Dechlorane Plus (DP) are not-yet they are increasingly used. There are no data on PHCs in coral reef biota from tropical islands in the western Indian Ocean (WIO).

Levels of DDTs and other organochlorine pesticides in healthy wild Nile crocodiles (Crocodylus niloticus) from a flagship conservation area.

Mass Nile crocodile (Crocodylus niloticus) deaths in Africa's premier conservation area, the Kruger National Park (KNP), prompted numerous studies to determine possible causes of the sudden die-offs. The majority highlighted the involvement of the anthropocene to crocodile mass mortalities. One of the potential causative agents was identified as legacy compounds such as organochlorine pesticides (OCPs) present in the various aquatic ecosystems of the KNP.

Polyhalogenated Compounds (Halogenated Natural Products and POPs) in Sardine () from the South Atlantic and Indian Oceans.

Halogenated natural products (HNPs) and persistent organic pollutants (POPs) were quantified in South African sardines () from one site in the South Atlantic Ocean and one in the Indian Ocean. At both sites, HNPs [2,3,3',4,4',5,5'-heptachloro-1'-methyl-1,2'-bipyrrole (Q1), mixed halogenated compound 1 (MHC-1), 2,4,6-tribromoanisole (2,4,6-TBA), 2'-MeO-BDE 68 (BC-2), and 6-MeO-BDE 47 (BC-3)] were 1 order of magnitude higher concentrated than anthropogenic POPs [mainly polychlorinated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), ∼3 ng/g lipids]. MHC-1 and Q1 were the major HNPs in the samples from both sites, contributing with up to 49 and 52 ng/g lipids, respectively.

Perfluoroalkyl substances (PFAS) in tern eggs from St. Brandon's Atoll, Indian Ocean.

Per- and polyfluoroalkyl substances (PFAS) are anthropogenic fluorinated compounds of concern for human and environmental health. There is no data on PFAS concentrations in marine bird eggs from the Western Indian Ocean. We analysed eight PFAS in eggs of fairy terns (Gygis alba), sooty terns (Onychoprion fuscatus), and common noddies (Anous stolidus) from St.

Impacts of a shallow shipwreck on a coral reef: A case study from St. Brandon's Atoll, Mauritius, Indian Ocean.

Shallow shipwrecks, can have severe ecological and toxicological impacts on coral atolls. In 2012, a tuna longliner ran aground on the reef crest of St Brandon's Atoll, Mauritius, broke up into three pieces which was moved by currents and storms into the lagoon. In the months following the grounding, the coral around the wreck became dead and black.

Occurrence, distribution, and ecotoxicological risk assessment of selected pharmaceutical compounds in water from Lake Victoria, Uganda.

The occurrence of 24 pharmaceuticals (including 15 antibiotics, three analgesic/anti-inflammatory drugs, three anti-epileptic/antidepressant drugs, two beta blockers, and one lipid regulator) was investigated in 75 water samples collected from four bays in the Ugandan part of Lake Victoria. In addition, the potential environmental risk of the target pharmaceutical compounds to aquatic organisms in the aquatic ecosystem of Lake Victoria was assessed. Water samples were extracted using solid phase extraction and analyzed for pharmaceuticals using high-performance liquid chromatography coupled with triple quadrupole mass spectrometry (LC/MS/MS).

Metal concentrations in corals from South Africa and the Mascarene Basin: A first assessment for the Western Indian Ocean.

Little knowledge exists on the state of metal contamination in corals from the Western Indian Ocean (WIO). Fragments of four soft and five hard coral genera were collected from five sites in the WIO- Sodwana Bay and Aliwal Shoal from South Africa, and Agalega, Rodrigues, and St. Brandon's Rock from the Mascarene Basin.

Halogenated and organophosphorus flame retardants in cetaceans from the southwestern Indian Ocean.

PBDEs, HBCD, DBDPE, PBEB and HBB, dechloranes and OPFRs, as well as natural MeO-PBDEs were monitored in muscle tissue of three dolphin species from the southwestern Indian Ocean (Delphinus delphis, Sousa plumbea and Tursiops aduncus) collected between 2012 and 2015. The mean PBDE concentration was 416 ± 333 ng g lw. BDE-47 was found in all samples and was almost half the total PBDE contamination.