Publications by authors named "Boutheina Jemli"

Invasive fungal infections (IFI) are emerging opportunistic diseases that occur mainly in immunocompromised patients. Our study aimed to analyze the epidemiology of IFIs in patients with hematological malignancies, and the prognostic factors. Our retrospective study included patients hospitalized in the hematology department between January 1, 2010, and August 31, 2020, and in whom the diagnosis of IFI was made according to the EORTC criteria 2008.

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Malignant external otitis (MEO) has a frequent bacterial origin, but we are currently witnessing the emergence of fungal agents, which poses difficulties in diagnosis and management. The aim of our work is to analyze the epidemiological and clinical profile of fungal MEO and to study the antifungal susceptibility of fungi involved. Our study is retrospective collecting 43 patients treated for fungal MEO between 2010 and 2019.

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Article Synopsis
  • Tinea capitis (TC) is a common fungal infection in children, particularly before puberty, with different dermatophytes identified across regions.
  • This study conducted a retrospective analysis of 474 patients from Tunis over eight years, revealing a 44.3% prevalence of TC and a higher occurrence in males, averaging 6.2 years of age.
  • The study identified five species of dermatophytes, mainly Microsporum canis, and emphasizes the importance of mycological examination for accurate diagnosis and treatment planning.
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Article Synopsis
  • Dematiaceous fungus is commonly found in nature and can lead to infections, notably in people with weakened immune systems.
  • A case involving a healthy woman showed a periorbital infection with unclear symptoms, which was diagnosed through a skin biopsy.
  • Despite receiving antifungal treatment, the condition progressed to a fatal outcome.
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Cryptococcosis is an opportunistic fungal infection that is commonly associated with an immune-compromised state. Cases of cryptococcosis have rarely been reported in patients with multiple myeloma (MM). However, cryptococcosis as a presenting symptom of MM has never been reported.

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Mucormycosis is a rapidly progressing and lethal infection caused by fungi of the order mucorales. The disease occurs mostly in patients with uncontrolled diabetes or other predisposing systemic conditions. We report a case of rhinofacial mucormycosis in a 39-year-old diabetic patient.

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Tetracycline resistance has been postulated as a potential phenotypic marker of livestock-associated lineage ST398 amongst meticillin-resistant Staphylococcus aureus (MRSA) clinical isolates in some European hospitals. The objective of this study was to determine if this marker could also be applied to Maghrebian countries. In total, 99 MRSA isolates were collected in a Tunisian hospital during January 2011-October 2012, and 24 tetracycline-resistant MRSA isolates of this collection were characterized.

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Twenty-eight vancomycin (VA)-resistant enterococci isolated from different patients (n = 16) and also from the environment (n = 12) were recovered in a Tunisian military hospital during 2012-2013. The mechanisms of resistance to VA and to other antibiotics as well as the presence of esp and hyl virulence genes were determined in these isolates by PCR, being their clonal relationship analyzed by pulsed-field gel electrophoresis (PFGE). VA resistance mechanisms detected were as follows (species-patient/environment): vanA (Enterococcus faecium, 13/5), vanC1 (Enterococcus gallinarum, 3/0), and vanC2 (Enterococcus casseliflavus, 0/7).

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Leishmaniasis is an infection caused by a protozoan parasite belonging to the genus Leishmania and transmitted by the Phlebotomus sandfly. We report a case of visceral leishmaniasis in a 49-year-old male renal transplant recipient, a resident of the western part of Tunisia, which is an endemic zone for the disease. Just before and after the transplantation, the patient resided in Tunis, which is non-endemic for leishmaniasis.

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