Cryosurgery and curettage-cryosurgery for basal cell carcinomas of the mid-face.

Background: Surgical treatment of basal cell carcinoma (BCC) can be technically difficult in mid-face area. Cryosurgery is proposed for low-risk BCC. Cryosurgery has been poorly investigated in mid-face BCC, which is considered as having a high risk of recurrence.

Treatment of earlobe keloids by surgical excision and cryosurgery.

Background: The long-term results of keloid treatments remain poor.

Objective: To assess the long-term efficacy of a technique combining surgical excision and immediate cryosurgery in patients with ear keloids.

Methods: A retrospective study was performed between January 2001 and June 2011.

[Cryosurgery and photodynamic therapy for the treatment of Paget's disease of the vulva: two cases].

Background: Surgery is the standard treatment for vulvar Paget's disease, despite its mutilating consequences and the high associated recurrence rate. Alternative treatments such as CO₂ laser, application of imiquimod and topical photodynamic therapy (PDT) have recently been proposed. We report on two patients with vulvar Paget's disease treated with combined cryosurgery and PDT.

Papular and annular fixed urticarial eruption: a characteristic skin manifestation in patients with relapsing polychondritis.

Background: Skin manifestations of relapsing polychondritis (RP) are usually nonspecific.

Objective: We report a series of patients with RP who presented with annular skin lesions.

Methods: The clinical and histologic features and follow-up data of patients with RP and an annular urticarial eruption were retrospectively reviewed.

[Treatment of keloids with shaving and cryosurgery: preliminary reports].

Introduction: Numerous treatments have been proposed in patients with keloid scars. Unfortunately, most exhibit poor efficacy. The preliminary results obtained in ten patients with large keloid scars treated by shaving followed by cryosurgery are reported.

[Evaluation of the diagnosis of pigmented tumors of the skin and factors leading to a decision to excise. Dermatologists of the Postgraduate Association of Haute-Normandie].

Introduction: The necessity of excising melanomas characterized by a slight thickness at an early stage, leads dermatologists to remove pigmented lesions which do not correspond to melanomas. The aims of this study were: a) to prospectively assess the accuracy of melanoma diagnosis, b) to quantify the number of excisions performed according to the degree of melanoma suspicion, c) to determine the specific clinical sign or signs of relevant diagnostic value.

Patients And Methods: This study was conducted prospectively from January 1996 to August 1997 by dermatologists in private practice and dermatologists from a University Hospital staff.

[Eczema-like cutaneous graft versus host disease treated by UV-B therapy in a 2-year-old child].

Introduction: Chronic graft versus host disease (GVHD) has rarely been reported in children. Optimal treatment should minimize infectious complications and preserve the child's growth. We report a case of cutaneous GVHD in a two year-old boy, who presented an eczema-like eruption and responded well to broad band UV-B therapy.

[Langerhans histiocytosis in adults: cutaneous and mucous lesion regression after treatment with thalidomide].

Background: Langerhans cell histiocytosis is a rare disorder with a wide spectrum of diseases and various clinical behaviours. The prognosis depends on the patient's age at onset and the extension of the disease. Treatment is function of evolution and extension of the disease.

[Melkersson-Rosenthal syndrome treated by thalidomide. 2 cases].

Introduction: Treatment of Melkersson-Rosenthal syndrome (MRS) remains uncertain. Two cases of MRS treated with thalidomide are described.

Case Report: Two patients with cheilitis granulomatosa and recurrent facial edema have been treated with thalidomide (100 mg daily) for 3 and 6 months respectively.

New electron microscopic findings in a case of multicentric reticulohistiocytosis. Long spacing collagen inclusions.

The case of a 68-year-old woman with polyarthropathy and skin nodules is presented. Histologic findings of histiocytes with ground-glass cytoplasm favored the diagnosis of multicentric reticulohistiocytosis. In this article we report new electron microscopic findings of intra- and extracytoplasmic long spacing collagen (type VI).

[Isolated zinc deficiency and necrolytic migratory erythema. Apropos of a case].

The case of 87-old year woman with necrolytic migratory erythematosus rash without elevated plasma enteroglucagon is discribed. Decreased serum zinc level, response to oral zinc substitution and follow up proved the zinc deficiency.

[Spontaneous rupture of subclavian artery disclosing Ehlers-Danlos disease. A case].

The authors report the case of a 30-year old man who suffered spontaneous rupture of the right subclavian artery. Treatment consisted of carotid-axillary graft since the fragility of the vessel precluded direct suture. The clinical symptoms, together with histological and ultrastructural examinations led to a diagnosis of Ehlers-Danlos syndrome with purely arterial manifestations.

[Cutaneous metastasis disclosing primary angiosarcoma of the aorta].

A 68-year old man presented with erythemato-telangiectatic nodules on his right lumbar fossa, associated with right-sciatica. A skin biopsy was performed. Microscopic examination showed tumour embolism in the lumen of the dermal vessels.

[Argyria in children].

A case of argyria in a 14 year-old child caused by abuse of silver containing pulveriser for sore throat is described. The distinctive skin blue gray discoloration that occurs in argyria is due to deposition of silver. Pigmentation is permanent.

[Acquired disseminated elastolysis of the mid-dermis].

A young woman in a good health noticed the occurrence of inelegant wrinkled plaques on her trunk and limbs. The histological aspect was particular in so far as there were no layers of elastic fibres left in the middermis. None of the classical diagnoses could be accepted.

[Type IV Ehlers-Danlos syndrome of acrogeria type].

A familial case of acrogeria, occurring in a mother and her daughter, is reported. A 12-year old mentally retarded girl was seen with a history of repeated ecchymoses despite normal hemostasis. On clinical examination, the skin was diffusely atrophic with atrophy and wrinkling most pronounced on the extremities.

HLA in familial malignant melanoma.

In a family displaying the familial atypical multiple-mole melanoma syndrome, linkage analyses were performed between HLA and an assumed dominant gene respectively determining each of the following affected phenotypes: precursor lesions; cutaneous malignant melanoma (CMM); and precursor lesions or CMM or both. The results suggest that there is a complex mechanism involving several factors, genetic and environmental interacting with the gene determining precursor lesions to cause the neoplastic transformation.