Publications by authors named "Bouker A"

Background: Testicular and epididymal sperm extraction surgery is a frequent procedure. However, to date, there has been no French consensus on the technique to be preferred in the various situations of male infertility and on the best way to perform them. We therefore decided to proceed with a formalized expert consensus, using the method recommended by the French National Authority for Health.

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  • * This study focuses on enhancing the genetic understanding of NOA by identifying new genes linked to the condition through exome sequencing of 96 individuals who previously tested negative for routine genetic abnormalities.
  • * Researchers found potentially causative genetic defects in 16 genes across 22 individuals, with a clear correlation between defects in meiotic genes and unsuccessful sperm retrieval, suggesting that genetic testing could help predict surgical outcomes for patients.
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  • * Researchers identified two rare loss-of-function variants in testis-specific genes through whole exome sequencing and verified their role using CRISPR/Cas9 to create knockout mice.
  • * The knockout mice exhibited normal fertility and sperm parameters, suggesting that the studied genes may not be essential for spermatogenesis, challenging previous assumptions about their role in male fertility.
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SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) metamorphosed our medical practice. In early June 2020, more than 6,400,000 COVID-19 (coronavirus-19 disease) cases were diagnosed across the world and more than 380,000 deaths were linked to COVID-19. Many medical symptoms of COVID-19 were reported.

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  • - Men with non-obstructive azoospermia (NOA) can potentially have viable sperm in their testes, and advanced sperm retrieval techniques like microdissection testicular sperm extraction (mTESE) are essential for improving fertility, with a sperm retrieval rate (SRR) of 60%.
  • - A study conducted on 1,050 NOA patients using a modified mTESE technique with 6-fold magnifying loupes resulted in finding sperm in 61% of cases on the first testis and increased the overall SRR from 43% to 51.8%.
  • - This modified mTESE technique is effective and reliable for institutions lacking an operating microscope, making it particularly beneficial for patients with
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Thrombotic events occurring in the course of celiac disease are frequently reported in the literature. The localization is often unusual, mainly affecting the hepatic veins. To our knowledge, this is the first report of intracardiac thrombosis occurring in a patient with celiac disease.

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Background: Congenital bilateral absence of vas deferens (CBAVD) is responsible for 2-6% of male infertility. It occurs in 95% of men with cystic fibrosis. This malformation is present in patients with a sterile obstructive azoospermia but without clinical evidence of cystic fibrosis.

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Background: Laparoscopic radical prostatectomy was a major breakthrough in the treatment of localized prostate cancer.

Aim: To report the first two laparoscopic radical prostatectomies performed in Tunisia.

Cases Report: The two patients are aged 57 and 66 and were suffering from localized prostate cancer.

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Objectives: The objective of this study was to analyse all attempts of ICSI performed in our centre between 1995 and 1997 with surgically harvested sperm for the treatment of secretory and excretory azoospermia.

Material And Methods: 71 infertile couples, in which the man suffered from secretory (n = 8) or excretory azoospermia (n = 63), were managed with 94 attempts of ICSI.

Results: ICSI was able to be performed 85 times with 82 embryo transfers resulting in 29 clinical pregnancies.

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When ureteral rupture is suspected after trauma with fracture of the pelvis, insertion of a suprapubic catheter is required as an emergency measure. Ureteral lesions must be repaired early by the 5th to 10th day after trauma. Pyelography or retrograde ureterography is required to determine whether there is total or partial rupture and the degree of damage is identified endoscopically.

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In March 1985, we realised the first Bordeaux neo-bladder, with detubularized ileo-colic segment (15 cm of ascending colon and 20 to 25 cm of ileum). The urethra is anastomosed at the lowest point of the caecum. 61 male patients underwent total replacement of the bladder, and we analyse the results in 24 of them, with a follow up more than 2 years.

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