Leishmaniases are a group of infectious diseases caused by protozoan parasites and are transmitted by the bites of infected phlebotomine sandflies. The heterogeneity of these diseases is influenced by both parasitic properties and host factors. Cutaneous leishmaniasis (CL) is a major public health problem in Morocco, where the geographical expansion of CL (particularly CL caused by ), the heterogeneous appearance of lesions and the difficulty in diagnosing CL contribute to late diagnosis of CL and delayed treatment of patients.
View Article and Find Full Text PDFAdvanced melanoma patients who failed anti-PD-1 therapy have limited options. We analyzed a cohort of 133 advanced melanoma patients receiving anti-PD-1 monotherapy in a referral center between April 2015 and December 2017, and included the 26 patients with confirmed progressive (PD) or stable disease who received additional radiotherapy with an unmodified anti-PD-1 mAb regimen. Tumor evaluations were done on radiated and nonradiated (RECIST 1.
View Article and Find Full Text PDFBackground: Pemphigus is an autoimmune bullous disease affecting the skin and mucous membranes. Associated nail involvement is underestimated and is characterized by a variety of clinical manifestations. Our aim was to describe the clinical aspects of nail involvement during pemphigus.
View Article and Find Full Text PDFPulsed dye laser (LCP) is currently the gold standard for Port wine stains (PWS) treatment. However, predictive clinical criteria indicating a right or poor response are not yet clear in our context. This study aims to determine the factors associated with poor/good response in Moroccan patients with PWS treated with LCP.
View Article and Find Full Text PDFSpindle cell hemangioma, formerly known as spindle cell hemangioendothelioma, was described by Weiss and Enzinger in 1986. Since the advent of immunohistochemical studies it is no longer considered as low grade angiosarcoma. It is a benign vascular tumor It almost exclusively affects the dermis at the distal ends.
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