A free time point model for dynamic contrast enhanced exploration.

Dynamic-Contrast-Enhanced (DCE) Imaging has been widely studied to characterize microcirculatory disorders associated with various diseases. Although numerous studies have demonstrated its diagnostic interest, the physiological interpretation using pharmacokinetic models often remains debatable. Indeed, to be interpretable, a model must provide, at first instance, an accurate description of the DCE data.

Assessment of BOLD response in the fetal lung.

Objective: Assessment of lung development and maturity is of utmost importance in prenatal counseling. Blood oxygen level-dependent (BOLD) effect MRI was developed for functional evaluations of organs. To date, no data are available in fetal lungs and nothing is known about the existence of a BOLD effect in the lungs.

Gray-level discretization impacts reproducible MRI radiomics texture features.

Objectives: To assess the influence of gray-level discretization on inter- and intra-observer reproducibility of texture radiomics features on clinical MR images.

Materials And Methods: We studied two independent MRI datasets of 74 lacrymal gland tumors and 30 breast lesions from two different centers. Two pairs of readers performed three two-dimensional delineations for each dataset.