Publications by authors named "Bouaziz Amira"

Antimicrobial resistance among bacteria present in ready-to-eat foods is an emerging concern. Hence, this study investigated the presence of extended-spectrum and AmpC β-lactamases (ESBL/AmpC)-producing Enterobacterales (ESBL-E) and the dissemination of mcr-1 in ESBL-E from ready-to-eat food samples (RTE) in Algeria. RTE food samples (n = 204) were aseptically collected and selectively cultured using MacConkey agar.

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Vibrio species are geographically spread in marine habitats. Their virulence is often associated with the acquisition of mobile genetic elements such as phages. These phages can lysogenize the host cell by stably integrating their genomes into the host genome as prophages using the host or phage-encoded recombinases.

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Over the last few decades, species have been recognized as a promising source of new compounds with numerous pharmacological activities. Therefore, the antioxidant activity of leaves extracts was evaluated and then confirmed as well as the antidepressant-like and toxicological effects of the extracts. The ethyl acetate fraction (Rt EtOAcF) followed by hydroalcoholic extract (Rt EtOH-HO) showed a remarkable antioxidant activity.

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The emergence of carbapenemase-producing Enterobacteriaceae is of great concern to public health worldwide. The aim of this study was to screen for the presence of carbapenemase-producing Enterobacteriaceae in white stork (Ciconia ciconia) migratory bird stools, and to investigate their molecular support on β-lactamase production. In March 2015, 32 fecal samples of white stork were collected in the Commune of El Madher Wilaya de Batna, in eastern Algeria.

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Unlabelled: This study was undertaken to investigate the antibacterial and antifungal activities of Rumex tingitanus leaves extracts as well as the identification of bioactive components and their performance in meat preservation. Total phenolics and flavonoids showed the highest content of phenolics and flavonoids in the ethyl acetate fraction (Rt EtOAcF). For antimicrobial efficacy, leaves extract and derived fraction were tested for their capacity to inhibit bacterial and fungal proliferation in vitro and in vivo.

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Article Synopsis
  • The natural alkaloid N-methylisosalsoline, extracted from Hammada scoparia leaves, shows promising activity against the human 20S proteasome, indicating its potential as a basis for new anticancer drugs.
  • A new series of isosalsoline-type alkaloids were synthesized, featuring variations at specific positions, achieved through a method called Bischler-Napieralski cyclization.
  • The process included an innovative double reduction of nitroalkene to create the necessary substrate for building complex tetrahydroisoquinoline structures.
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Article Synopsis
  • - The study investigates the protective effects of a flavonoid-enriched fraction from Hammada scoparia against liver damage caused by ischemia/reperfusion injury during liver surgeries or transplants.
  • - Rats were divided into five groups to assess the impact of pharmacological preconditioning and technical postconditioning, revealing that the flavonoid treatment significantly reduced liver injury markers and enhanced antioxidant enzyme levels.
  • - The combination of pharmacological preconditioning and postconditioning showed superior effectiveness in minimizing oxidative stress and improving liver morphology compared to using either treatment individually, suggesting its potential as a therapeutic agent for hepatic IRI.
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16-hydroxy-methyl-12-methoxy-ibogamine), C(21)H(28)N(2)O(2), was prepared by reaction of ibogaine with a formaldehyde-acetic acid solution (pH = 4). The crystal structure of this new product, belonging to the iboga indole family, is stabilized by an inter-molecular O-H⋯N hydrogen bond. The identity of the compound was confirmed by one- and two-dimensional NMR spectroscopic techniques.

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1,2-dimethyl-6-meth-oxy-1,2,3,4-tetra-hydro-isoquinolin-7-ol), C(12)H(17)NO(2), is a major alkaloid isolated from Hammada scoparia leaves. It belongs to the isoquinoline family and it was characterized by NMR spectroscopy and X-ray crystallographic techniques. The absolute configuration could not be reliably determined.

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