Publications by authors named "Bottazzi L"
Introduction: Leber hereditary optic neuropathy (LHON) is among the most frequent inherited mitochondrial disease, causing a severe visual impairment, mostly in young-adult males. The causative mtDNA variants (the three common are m.11778 G>A/MT-ND4, m.
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- The study aimed to evaluate the treatment response of macular neovascularization (MNV) linked to age-related macular degeneration (AMD) with subclinical angioid streaks (AS) over a 2-year period.
- Researchers conducted a retrospective study comparing patients with subclinical AS to a control group without AS, analyzing factors such as the number of anti-VEGF injections and visual acuity outcomes.
- Results showed that patients with subclinical AS required more injections, experienced a decrease in visual acuity, and had higher rates of retinal pigment epithelium atrophy compared to those without AS, indicating poorer treatment outcomes.
Purpose: To report a case illustrating the association of Steinert Disease (SD) with peripheral retinal non-perfusion areas and epiretinal membrane.
Methods: Case report.
Results: A 47-year-old Caucasian female diagnosed with SD was referred for blurred vision in her right eye (RE).
Purpose: To investigate the associations between visual acuity (VA) and structural optical coherence tomography (OCT) features in retinal vein occlusion (RVO) eyes after cystoid macular oedema (CMO) regression and to assess whether inner retinal thinning is progressive.
Methods: Retrospective observational study of RVO eyes with regressed CMO for at least 6 months. OCT scans at CMO regression were analysed, and features were correlated with VA at that visit.
Introduction: In current clinical practice, several optical coherence tomography (OCT) biomarkers have been proposed for the assessment of severity and prognosis of different retinal diseases. Subretinal pseudocysts are subretinal cystoid spaces with hyperreflective borders and only a few single cases have been reported thus far. The aim of the study was to characterize and investigate this novel OCT finding, exploring its clinical outcome.
View Article and Find Full Text PDFBackground: The diagnosis of inherited retinal diseases (IRDs) can only be confirmed through genetic testing. The aim of our study is to investigate the propensity of Italian patients affected by IRDs to undergo genetic testing.
Materials And Methods: One hundred and thirty-two patients diagnosed with IRDs referred to Italian Retina Onlus were enrolled from 1 January 2021 to 31 December 2021 in this cross-sectional study to answer to a twelve-item questionnaire.
The manuscript aims at providing an overview of the published algorithms/automation tool for artificial intelligence applied to imaging for Healthcare. A PubMed search was performed using the query string to identify the proposed approaches (algorithms/automation tools) for artificial intelligence (machine and deep learning) in a 5-year period. The distribution of manuscript in the various disciplines and the investigated image types according to the AI approaches are presented.
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