Publications by authors named "Botros Rizk"

Article Synopsis
  • - High ovarian response to stimulation is identified by having more than 18-20 follicles or oocytes, indicating a risk for complications like ovarian hyper-stimulation syndrome (OHSS).
  • - Diagnosis of high response can occur before or after oocyte retrieval, and is influenced by ovarian reserve markers like AMH and AFC, especially in women with PCOS.
  • - Effective management strategies involve personalized treatment plans based on monitoring, which can help reduce the risk of OHSS for those identified as high responders.
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Ovarian hyperstimulation syndrome (OHSS) is typically iatrogenic following the administration of gonadotrophins. Sporadic and familial cases of spontaneous OHSS have generated an interest in genetic mechanisms for OHSS independent of exogenous gonadotrophins. The genetic studies have addressed the genes and receptors for FSH and luteinizing/human chorionic gonadotrophin hormones.

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Objectives: The purpose of this research was to study the independent effect of the amino acid glutamine on preimplantation mouse embryo development in vitro.

Study Design: Two-cell stage mouse embryos were cultured in human tubal fluid medium in the presence and absence of 1 mmol/L of glutamine. Outcomes for morphology and cleavage rates were compared with Fisher's and Mann-Whitney's tests, respectively.

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