Development of single-sided structure collimation film for direct-lit collimated backlight module.

In this paper, we proposed an optical structure to enhance the collimation and uniformity of 405 nm LED backlight modules. The structure is called a single-sided structure collimation film (SSSCF), which consists of a lenticular lens array, slit apertures, and a highly reflective coating surface. A lenticular lens array with slit apertures converts the angle of diffusive incident light into collimated light.

Effect of ultrasonic assisted EDM based on horizontal vibration on deep and small hole machining.

With the development of science and technology, industrial production requires more and more precise parts processing, precision processing has become a trend. In this trend. The traditional processing methods have been difficult to meet the market demand for micro-hole parts.

Trivalent Phosphine-Catalyzed [4+1] Spiro-annulation Reaction Using Allenyl Imide and Methylene Cyclocompounds.

The trivalent phosphine-catalyzed [4+1] spiro-annulation reaction of allenyl imide and activated methylene cyclocompounds has been developed for the construction of various spiro-2-cyclopenten-1-ones. Oxindoles, 3-isochromanones, and 2-indanones are selected as 1C synthons to capture the in situ-generated bis-electrophilic α,β-unsaturated ketenyl phosphonium intermediate, affording the corresponding monospiro- and bispiro-cyclopentenones in good to excellent yields (≤91%) under mild conditions. The primary attempt at asymmetric catalysis using monophosphine ()-SITCP provides promising enantioselectivity (45% ee).

Silane modified upconversion nanoparticles with multifunctions: imaging, therapy and hypoxia detection.

Herein, we report a facile route to synthesize silane coated upconversion nanoparticles (UCNPs@silane) with an ultrathin layer (the thickness: 1-2 nm), which not only provides good biocompatibility, but also affords hydrophobic interspace to load organic molecules to realize multifunctions. Besides the function of upconversion imaging of UCNPs, cancer therapy and oxygen level detection can also be realized by the addition of chemotherapy drug, PTX, and oxygen sensitive molecules, Platinum (II) octaethylporphine (PtOEP). In bio-experiments, besides the MTT assays, therapy efficacy of UCNPs@PTX@silane can also be detected with the confocal laser scanning microscopy (CLSM) by staining methods.

Amphiphilic silane modified NaYF4:Yb,Er loaded with Eu(TTA)3(TPPO)2 nanoparticles and their multi-functions: dual mode temperature sensing and cell imaging.

Rare-earth upconversion nanophosphors (UCNPs) have become one of the most promising luminescent materials for bio-applications, but their use still meets some limitations by difficulties in obtaining biocompatible UCNPs. To address this problem, we have developed a simple and versatile strategy for converting hydrophobic UCNPs into hydrophilic ones by amphiphilic silane modification with ultrathin thickness at room temperature (RT). In this strategy, the coating layers can also afford the place for loading with Eu(TTA)3(TPPO)2 complex which displays down conversion luminescence (DCL).

Glutathione modified gold nanorods with excellent biocompatibility and weak protein adsorption, targeting imaging and therapy toward tumor cells.

The non-specific interaction between the surface of gold nanorods (GNRs) and biomolecules is a significant problem in hyperthermia applications. In this work, a novel surface modification strategy was performed using zwitterionic oxidized glutathione (GSSG) to modify the GNRs through robust Au-S bond formation. The GSSG-GNRs were stable in aqueous solution over a broad range of pH and high ionic strength values.

Phase transition, size control and color tuning of NaREF4:Yb3+, Er3+ (RE = Y, Lu) nanocrystals.

It is important to finely tune the upconversion (UC) properties through controlling size and structure of upconversion nanocrystals (UCNCs) and improve their efficiency. Recently, it was reported that the UC luminescence (UCL) intensity of NaLuF4:Yb(3+), Er(3+) UCNCs could be tremendously improved compared to the most efficient NaYF4:Yb(3+), Er(3+) under 980 nm excitation. In this paper, we first studied the varied size control and phase transition properties of NaREF4:Yb(3+), Er(3+) (RE = Y, Lu) UCNCs prepared by the solvothermal method.

Multifunctional Au@mSiO2/rhodamine B isothiocyanate nanocomposites: cell imaging, photocontrolled drug release, and photothermal therapy for cancer cells.

The synthesis of Au@mesoporous SiO(2)/rhodamine B isothiocyanate (Au@mSiO(2)/RBITC) composite nanoparticles (NPs) is presented and their unique biofunctional properties are studied. The structure and morphology of the NPs are characterized by X-ray powder diffraction, transmission electron microscopy, and Fourier transform infrared spectroscopy. These NPs can not only be functionalized for fluorescence imaging, but also possess well-defined mesopore structures for drug loading and strong infrared surface plasmon absorption for light-controlled drug release and photothermal therapy for cancer cells.

The up-conversion luminescent properties and silver-modified luminescent enhancement of YVO4:Yb3+, Er3+ NPs.

In this paper, the unique up-conversion luminescence (UCL) properties of as-prepared and annealing YVO(4):Yb(3+), Er(3+) nanoparticles (NPs, ∼100 nm) and the corresponding YVO(4):Yb(3+), Er(3+)@Ag hybrids under 980 nm excitation were systemically studied through power-dependent, temperature-dependent emission spectra and dynamics. It is interesting to determine that the radiative transition rate of (2)H(11/2)/(4)S(3/2)-(4)I(15/2) for Er(3+) ions in YVO(4) is about an order of magnitude faster than that in the other hosts due to the wave function coupling with the 3d orbital of V(5+) and, thus, the up-conversion (UC) green emissions of YVO(4):Yb(3+), Er(3+) NPs is efficient. In addition, efficient novel UC broad band centering around 630 nm (1.

Selective photothermal therapy for breast cancer with targeting peptide modified gold nanorods.

In this work, we prepared polyacrylic acid (PAA) coated gold nanorods (GNRs) and then the targeting peptide modified GNRs. The biocompatibility and stability of functionalized GNRs were investigated by monitoring the surface plasmon resonance (SPR) absorption intensity. The efficacy of targeted thermal therapy can be significantly enhanced via decoration with surface-bound peptide which was obtained through phage display technology.

The inhibitory effect of polypeptide cSN50 on alcoholic hepatic injuries through blocking the binding of NF-κB to importin α.

Objective: To study whether alcohol and endotoxin induce inflammation, apoptosis, and expression of downstream genes TNF-α and caspase-3 through the nuclear transcription factor NF-κB, i.e., the IκB-NF-κB-importin α pathway.