Publications by authors named "Botagoz Joldybayeva"
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Synopsis of recent research by authors named "Botagoz Joldybayeva"
- Botagoz Joldybayeva's research primarily focuses on the mechanisms and roles of apurinic/apyrimidinic (AP) endonucleases in DNA repair pathways, emphasizing their functions in both base excision repair (BER) and nucleotide incision repair (NIR) across different species including humans and plants.
- One study revealed that the human thymine-DNA glycosylase (TDG) is not only involved in DNA repair but also plays a role in epigenetic regulation through DNA demethylation, demonstrating unique catalytic properties in specific contexts.
- Another significant finding involved the characterization of a wheat homologue of AP endonuclease, contributing to the understanding of DNA repair mechanisms in plants and highlighting the evolutionary conservation of DNA repair processes.
