Publications by authors named "Borui Yu"
Background: QiDiTangShen granules (QDTS), a traditional Chinese medicine (TCM) compound prescription, have remarkable efficacy in diabetic nephropathy (DN) patients, and their pharmacological mechanism needs further exploration.
Methods: According to the active ingredients and targets of the QDTS in the TCMSP database, the network pharmacology of QDTS was investigated. The potential active ingredients were chosen based on the oral bioavailability and the drug similarity index.
Context: Diabetic nephropathy (DN) is the main cause of end-stage renal disease. Modified Shen-Yan-Fang-Shuai formula (M-SYFSF) has excellent clinical efficacy in treating diabetic kidney disease. However, the potential mechanism of M-SYFSF remains unknown.
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- Diabetic nephropathy (DN) is a serious complication of diabetes characterized by proteinuria, which significantly impacts its progression, making protein reduction a key treatment goal.
- Traditional Chinese medicine (TCM) has been explored as a potential treatment option for managing proteinuria in DN, leading to this study's meta-analysis of its clinical effectiveness.
- The study will assess various randomized controlled trials using extensive databases and specific methodological guidelines to evaluate TCM's role in treating DN proteinuria, including its effectiveness and recurrence rates.
A Meta-Analysis of the Clinical Efficacy of TCM Decoctions Made from Formulas in the Liuwei Dihuang Wan Categorized Formulas in Treating Diabetic Nephropathy Proteinuria.
Evid Based Complement Alternat Med
September 2018
Objective: Diabetic nephropathy (DN) is one of the microvascular complications of diabetes mellitus. Proteinuria is the most important clinical characteristics of DN and an independent risk factor for disease progression of DN; reducing urine protein is the primary target of treatment strategies for DN. Liuwei Dihuang Wan Categorized Formulas (LDWCFs), a group of classic traditional Chinese medicine (TCM) formulas aiming at "kidney -tonifying", have been widely used in the treatment of DN.
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