Intranasal combo: fixed-dose combination of mometasone furoate and olopatadine hydrochloride in therapeutic strategies for rhinosinusitis.

A novel strategy for the treatment of allergic rhinitis results from the innovative combination of antihistamine and intranasal corticosteroid drugs. By combining two preparations with different mechanism of action, this novel approach facilitates quick and effective controls of all upper respiratory tract allergy symptoms. The article presents the results of a study of olopatadine hydrochloride and mometasone furoate fixed-dose combination (GSP301) administered intranasally from a spray formulation, with an attempt at positioning the treatment within the ARIA and EPOS guidelines.

Diet and selected elements of lifestyle in the Polish population before and during the COVID-19 pandemic - a population study.

Introduction And Objective: The COVID-19 pandemic led to the introduction of sanitary restrictions in many countries which necessitated numerous lifestyle changes, especially in the diet. The study aimed to compare the diet and selected lifestyle elements in the Polish population during the COVID-19 pandemic.

Material And Methods: The study group consisted of 964 individuals: 482 before the COVID-19 pandemic (composed using the Propensity Score Matching method) and 482 during the pandemic.

Vaccine equity in COVID-19: a meta-narrative review.

The topic of inequitable vaccine distribution has been widely discussed by academics, journalists and policy-makers in the context of the COVID-19 pandemic. However, research into perceptions of vaccine equity has been particularly neglected, resulting in a lack of universal understanding of vaccine equity. To address this, we conducted a meta-narrative review on COVID-19 vaccine equity according to the Realist And MEta-narrative Evidence Syntheses: Evolving Standards (RAMESES) publication standard.

Predictors of stress among dentists during the COVID-19 epidemic.

The aim of the study was to assess the relationship between personality traits, self-esteem and life satisfaction, and also the stress level, among dentists during the COVID-19 outbreak. In order to confirm our hypotheses, 310 active dentists aged 25-64 years who were practising during the first wave of COVID-19 in Poland were examined. The IPIP-BFM-20 self-report questionnaire was used to measure personality traits, the popular Rosenberg Self-Esteem Scale was used to assess self-esteem, the five-item Satisfaction with Life Scale was used to measure life satisfaction and the four-item version of the Perceived Stress Scale was used to measure stress.

Financing of Immunization Programs by Local Government Units in Poland as an Element of Health Policy.

Introduction: The scope and schedule of immunization in Poland is regulated by the Immunization Programme prepared and announced by the State Sanitary Inspector. There are two kinds of vaccines: compulsory vaccines, financed by the state budget at the disposal of the Minister of Health, and vaccines recommended by the central health authorities but financed by local governments within health policy programmes. Compulsory vaccines cover people up to 19 years of age and individuals at higher risk of infections.

Vitamin D and Dental Caries in Children with Growth Hormone Deficiency.

Vitamin D deficiency is a common risk factor for multifactorial diseases, and it seems to be associated with growth hormone deficiency (GHD). Vitamin D could prevent dental caries. The goal of this study was to identify whether there is an association between hormonal therapy with growth hormone (GH), vitamin D supplementation, vitamin D levels, and the occurrence of caries among children affected by GHD.

Extent of protective or allergy-inducing effects in cats and dogs.

Objective: The study aimed to assess the effect of fur-bearing pets, including cats and dogs, on the health of individuals with allergic conditions.

Material And Methods: The study group comprised 18,617 individuals (16,562 from urban and 2,055 from rural areas). The tool used in the study was the European Community Respiratory Health Survey (ECRHS) and International Study of Asthma and Allergies in Childhood (ISAAC) study questionnaire, adapted to European conditions (Middle and Eastern Europe) and used as part of the study Implementation of a System for the Prevention and Early Detection of Allergic Diseases in Poland.

The dependence of dental caries on oral hygiene habits in preschool children from urban and rural areas in Poland.

Introduction: Dental caries is considered to be a modern civilization disease;however, the state of oral health negatively influences psychological and sociological relations in children which leads to feelings of discomfort from early age.

Objective: The aim of study was evaluation of the association between incidence of dental caries (d3ft index) in preschool children from urban and rural areas, and determining the relationship between dental caries intensity and hygienic habits.

Materials And Method: 844 children aged 3-6 years from the city and the countryside were examined.

Career imperative. Is it legal? Is it ethical?

This paper gives sample ethical case vignettes and discussions that will be presented at the 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC'14) special session of the Ethics and Professional Responsibility Committee. The session includes additional cases with audience participation and panel discussions.

Current nutritional status of patients with rheumatic diseases in the population of Poland.

The Aim Of The Study: The aim of the study was to evaluate the current state of nutrition of patients with rheumatic diseases in the Polish population.

Material And Methods: An anonymous questionnaire study was carried out among the patients of the Institute of Rheumatology in Warsaw in the fourth quarter of 2012. Five hundred questionnaires were distributed, and 397 questionnaires were collected and accepted for further analysis (response rate = 79%).

Analysis of vector models in quantification of artifacts produced by standard prosthetic inlays in Cone-Beam Computed Tomography (CBCT)--a preliminary study.

Cone-beam computed tomography (CBCT) is a relatively new, but highly efficient imaging method applied first in dentistry in 1998. However, the quality of the obtained slices depends among other things on artifacts generated by dental restorations as well as orthodontic and prosthetic appliances. The aim of the study was to quantify the artifacts produced by standard prosthetic inlays in CBCT images.

Life style and risk of development of dental caries in a population of adolescents.

Introduction: Oxygen is an essential element for sustaining the life of aerobes; however, in certain conditions it may be toxic for these organisms. This is due to so-called reactive oxygen species - ROS. Factors which cause the production of free radicals include ionizing radiation, UV radiation, high temperature, and hazardous substances, such as phenols, carbon monoxide, e.

Incidence of abnormalities in temporomandibular joints in a population of 1,100 urban and rural patients lacking teeth and other parafunctions in 2003-2008. An international problem.

Introduction And Objective: A hectic lifestyle and everyday stress are direct causes of parafunctions. The objective of the presented study was to examine the relation of sleep disorders, distant pain symptoms, symptoms of pathological tooth wear in rural and urban patients with parafunctions.

Materials And Methods: The patient group consisted of 836 women and 274 men aged 9-82, and divided into groups taking into account the following criteria: number of patients in certain age groups, number of women and men, place of residence, presence of missing teeth problem, presence of occlusal and non-occlusal parafunctions, symptoms of tooth wear, distant pain symptoms, and sleep disorders.

The relationship between antibiotic therapy in early childhood and the symptoms of allergy in children aged 6-8 years - the questionnaire study results.

Introduction: Studies based on the ISAAC questionnaire suggest a correlation between the use of antibiotics and the prevalence of asthma and allergy in children aged 6-7 years. The number of courses of antibiotic therapy is an important factor.

Objectives: To investigate the relationship between the use of antibiotics during the first years of life and the prevalence of allergy and asthma among children (aged 6-8 years) in the urban population of Poland.

Correlation between eye and ear symptoms and lack of teeth, bruxism and other parafunctions in a population of 1006 patients in 2003-2008.

Introduction: Parafunctions (harmful habits) play a crucial role in the formation of temporo-mandibular joint (TMJ) dysfunction syndrome with disc displacement. Disorder symptoms in temporo-mandibular joints manifest themselves in the eye and ear but are usually not associated with the dysfunction of temporo-mandibular joints and that might lead to errors in diagnosis. The aim of the study was to examine the influence of missing teeth and parafunctions on the occurrence of ear and eye symptoms in patients treated in the Department of Prosthodontics of the Medical University of Lublin.

Nodular cutaneous amyloidosis.

A 56-year-old white man presented with a lesion on the right shoulder. The lesion developed during a short period and recently became irritated with occasional bleeding and mild pruritus. The patient denied pain.

Cutaneous amyloidosis.

Amyloidosis is generally classified as either systemic or cutaneous, with both primary and secondary forms. There are also heredofamilial and hemodialysis-associated varieties of amyloidosis, all with specific amyloid fibril derivatives. Nodular cutaneous amyloidosis is the most rare form of primary cutaneous amyloidosis.

Filaggrin gene defects are independent risk factors for atopic asthma in a Polish population: a study in ECAP cohort.

Background: FLG null variants of which 2282del4 and R501X are the most frequent in Caucasians are established risk factors for atopic dermatitis (AD) with an effect probably mediated through impairment of epidermal barrier. Among subjects with AD FLG defects are also consistently associated with asthma and allergic rhinitis (AR) but it is less clear to what extent these associations are also present independently from skin disease. The aim of the present study was to evaluate the role of 2282del4 and R501X in predisposing to these allergic phenotypes in a Polish population.

Subcutaneous fat necrosis/panniculitis and polyarthritis associated with acinar cell carcinoma of the pancreas: a rare presentation of pancreatitis, panniculitis and polyarthritis syndrome.

An 82-year-old man presented with a two-week history of three painful, inflamed nodules on his lower extremities with symmetric arthritis of multiple joints. He was under the care of hospice for end-stage acinar cell carcinoma of the pancreas. His serum amylase and lipase levels were markedly elevated.

Prevalence of rhinitis in Polish population according to the ECAP (Epidemiology of Allergic Disorders in Poland) study.

Unlabelled: The prevalence of allergic disorders, especially allergic rhinitis (AR), has dramatically increased in the past few decades and multicentre, standardized, randomized epidemiological studies are required to quantify this phenomenon in Poland.

Aim: The aim of the study was to estimate the prevalence of rhinitis and allergic rhinitis in Poland.

Material And Method: The ECAP study was conducted using the ECRHS II and ISAAC questionnaires translated into the Polish language and validated, in selected nine regions of Poland, including eight cities and one rural area.

Diagnostic abilities of three-dimensional electronic axiography on the basis of ARCUSdigma device.

The ARCUSdigma is an electronic facebow enabling presentation and graphic analysis of mandibular movements on the computer screen. A kinematic hinge axis of the mandible can be determined using this device. The paper presents the diagnostic potential of the ARCUSdigma in relation to programming an articulator according to individual parameters of mandibular movements of the patient and its application in the diagnosis of temporo-mandibular joints.

Iatrogenic pain dysfunction syndrome of the masticatory system--case study.

A female patient, age 71, came to The Department of Prosthetic Dentistry University School of Medicine in Lublin with pain dysfunction syndrome after treatment by extensive prosthesis of upper and lower dental arches. After examination many abnormalities of prosthetic restorations were ascertained. After 21 months of repositioning occlusal splint treatment the symptoms of pain dysfunction were gone, which permitted final prosthetic restoration.

[Massive pulmonary embolism during pregnancy treated with streptokinase and complicated by massive haemorrhage--a case report].

A case of a 27-year-old pregnant female (first trimester) is described. The patient was hospitalised due to pregnancy complications and immobilised for 3 weeks. At the end of this period patient's clinical condition rapidly deteriorated and she developed shock, followed by cardiac arrest.

Gender dimorphism in differential peripheral blood leukocyte counts in mice using cardiac, tail, foot, and saphenous vein puncture methods.

BACKGROUND: In many animal models that investigate the pathology of various diseases, there is a need to monitor leukocyte counts and differentials. However, various researchers use a range of different techniques in male and female laboratory animals to collect such blood variable information. These studies are then compared to one another without consideration of the possibility that different bleeding sites or techniques as well as gender may produce varying results.