Cluster sets and traditional sets elicit similar muscular hypertrophy: a volume and effort-matched study in resistance-trained individuals.

Background And Objective: Previous studies examining the effects of cluster sets (CS) compared to traditional sets (TS) protocols on muscle hypertrophy have primarily equated to volume load. This inevitably has resulted in a lower number of repetitions performed in TS compared to CS, thereby leading to a suboptimal hypertrophic stimulus. The present study aimed to compare the impact of CS and TS protocols, both performed with the same number of sets and repetitions, but with loads adjusted to the same range of repetitions in reserve (RIR) on muscle hypertrophy.