[The significance of choroidal neovascularization type in predicting the effectiveness of antiangiogenic therapy].

Neovascular age-related macular degeneration (nAMD) is one of the causes of irreversible visual acuity loss. Intravitreal injections of anti-vascular endothelium growth factor (anti-VEGF agents) have been proved to be an effective treatment of nAMD. Among the topical problems of this type of treatment is the possibility for predicting the response of different types of choroidal neovascularization (CNV) to the anti-VEGF therapy.

[Intravitreal aflibercept in high retinal pigment epithelial detachments].

Purpose: To study the effectiveness of intravitreal aflibercept in high pigment epithelium detachment (PED) in eyes with age-related macular degeneration (AMD).

Material And Methods: This study included 16 eyes of 16 patients (10 female and 6 male) aged 52 to 82 years (mean age 68.56±2.

[True tolerant intraocular pressure in glaucoma, ocular hypertension and low-tension glaucoma].

Measurements of the true tolerant intraocular pressure (IOP) in 500 eyes of 384 patients with primary glaucoma and in 26 eyes of 13 patients with ophthalmic hypertension have demonstrated that the value of the true tolerant 10P is close to the lowest border of the mean statistical range of normal ophthalmic tone values, this value being, on an average, 13.4 mm Hg in primary glaucoma and 10.2 mm Hg in low-pressure glaucoma, whereas in ophthalmic hypertension it has been much higher - 24.

[Significance of the intolerance index in glaucoma].

In 1979 Vodovozov proposed a new individualized index-the intolerance index-for the prognosis of glaucoma. It is calculated as the difference between tonometric and tolerable intraocular pressure, determined after the intake of hypotensive drugs. The lowered tonometric value which coincides with the maximum improvement in visual function (reduced size of the blind spot, enlarged visual field) is considered the individually compatible (tolerable) level of intraocular pressure.

[Perimetric and visumetric methods for measuring individually tolerated intraocular pressure in glaucoma].

These techniques are used in far-advanced cases of glaucoma when the campimetric method is not practicable due to a considerable loss of visual field. The patient takes a mixture of glycerol and ascorbic acid as a hypotensive agent, his visual field or visual acuity and intraocular pressure are checked every 30 minutes. The intraocular pressure determined together with the maximum field size or with the best visual acuity is considered the individually tolerated value.