Publications by authors named "Boris Martynov"
This study is to analyze fluorescence sensitivity in the diagnosis of brain and spinal cord tumors. The authors conducted a multicenter retrospective analysis of data on 653 cases in 641 patients: 553 of them had brain tumors and 88 spinal cord tumors. Brain tumor resection was performed in 523 patients, of whom 484 were adults and 39 children.
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- Surgical resection of gliomas in critical brain areas carries a high risk of neurological deficits and impacts quality of life, but alternatives exist.
- Modern neuroimaging and neuronavigation allow for minimally invasive treatments like stereotactic cryodestruction, which was studied in 88 patients with various glioma grades that were not suitable for traditional surgery.
- The results showed low mortality and complication rates, with most neurological issues being temporary; median survival rates were promising compared to historical data, suggesting that cryodestruction could be a viable option for managing unresectable gliomas.
While some avian retroviruses have been shown to induce gliomas in animal models, human herpesviruses, specifically, the most extensively studied cytomegalovirus, and the much less studied roseolovirus HHV-6, and Herpes simplex viruses 1 and 2, currently attract more and more attention as possible contributing or initiating factors in the development of human brain tumors. The aim of this review is to summarize and highlight the most provoking findings indicating a potential causative link between brain tumors, specifically malignant gliomas, and viruses in the context of the concepts of viral oncomodulation and the tumor stem cell origin.
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