Vaccination opportunity in children up to 6 months old born in 2017 and 2018 in the city of Londrina-PR, Brazil: a population-based survey.

Objective: To evaluate opportunity for vaccination in children born alive in Londrina, up to 6 months old and the relationship between socioeconomic stratum and vaccination regularity.

Method: Population survey study based on a retrospective cohort of children born in 2017 and 2018 that identified vaccines not administered in a given session. Vaccination regularity was compared between socioeconomic strata using Pearson's chi-square test.

Vaccination coverage in children up to 2 years old born in 2017 and 2018 in the municipalities of São Paulo and Campinas, Brazil: comparison of the results of a national survey and the National Immunization Program Information System.

Objective: To estimate and compare vaccination coverage among children born in 2017-2018 in São Paulo and Campinas, according to the Vaccination Coverage Survey (ICV 2020) and the National Immunization Program Information System (SI-PNI).

Methods: ICV 2020 analyzed vaccination card records. Coverage was calculated and compared to doses recorded on the SI-PNI, divided by the target population.

Factors associated with vaccination coverage in children up to 15 months old, born in 2017-2018 in the city of Natal/RN, Brazil: a population-based survey.

Objective: To estimate vaccination coverage and analyze factors associated with full vaccination among children up to 15 months old in the city of Natal-RN, Brazil.

Methods: Population-based survey with data recorded on children's vaccination cards and interviews conducted in 2020 and 2021. Analysis of factors associated with complete vaccination was performed by calculating prevalence ratios (PR) and 95% confidence intervals (95%CI) using Poisson regression.

Analysis of polio vaccination status in a cohort of live births in 2017 and 2018 in Brazilian cities: a national vaccination coverage survey.

Objective: To describe the polio vaccination status in 26 state capitals, the Federal District, and 12 municipalities in Brazil, among children born between 2017 and 2018.

Methods: This was a population-based household survey conducted from 2020 to 2022, which assessed polio vaccination coverage in children, considering valid, administered, and timely doses by municipality.

Results: Data were collected from 37,801 children.

Vaccination coverage, vaccine hesitancy and factors associated with incomplete vaccination: a household survey conducted with children born between 2017 and 2018 in the inland municipalities of Northeastern Brazil.

Objective: To analyze vaccination coverage and factors associated with incomplete vaccination in inland municipalities of Northeastern Brazil.

Methods: This was a household survey using cluster sampling conducted in Vitória da Conquista, Bahia state, Caruaru, Pernambuco state, Sobral, Ceará state and Imperatriz, Maranhão state between 2020 and 2022. Vaccination coverage by valid doses and vaccine hesitancy were analyzed, with the odds ratio (OR) estimated and adjusted using logistic regression.

Vaccination coverage and factors associated with incomplete polio vaccine schedule in children born in 2017-2018, in state capitals and interior region municipalities of Northeast Brazil.

Objective: To analyse vaccination coverage and factors associated with incomplete polio vaccination in a cohort of children born in 2017-2018, in state capitals and interior region municipalities of Northeast Brazil.

Methods: Household survey of children aged ≤24 months conducted between 2020 and 2022. Vaccination coverage and dropout rates were estimated, as well as factors associated with incomplete vaccination, analyzed by calculating odds ratios (OR) and 95% confidence intervals (95%CI).

Vaccination coverage, delay and loss to follow-up of the triple viral vaccine, in live births between 2017 and 2018 in Brazilian cities.

Objective: To estimate measles-mumps-rubella vaccination coverage, delay and loss to follow-up in children up to 24 months old living in Brazilian cities.

Methods: Surveys and questionnaires with a retrospective cohort of live births in 2017-2018, analyzing vaccination coverage and sociodemographic data of children and families, based on vaccination card records and interviews.

Results: Valid coverage of first dose was 90.

Factors associated with vaccination coverage: a population-based survey in Vitória, Espírito Santo, Brazil, 2020-2021.

Objective: To estimate prevalence of the full vaccination schedule for children 12 to 24 months old and to analyze associated factors.

Methods: Survey with cluster sampling carried out in Vitória, Espírito Santo, Brazil, between December 16, 2020, and January 4, 2021. Children born in Vitória in 2017 and 2018 were included.

Vaccine hesitancy and consequences for vaccination coverage in children at 24 months of age, born in 2017-2018, living in the state capitals, Federal District and 12 inner region cities of Brazil.

Objective: To analyze vaccine hesitancy associated factors and repercussions on vaccination coverage.

Methods: Cohort of children born in 2017-2018, living in Brazilian state capitals, Federal District (FD), and 12 inner region cities, stratified by socioeconomic level. National Vaccination Coverage Survey (2020) data on hesitancy, access and programmatic difficulties were obtained by interview and coverage was calculated from vaccination card dose and date records.

Multivariable MR Can Mitigate Bias in Two-Sample MR Using Covariable-Adjusted Summary Associations.

Genome-wide association studies (GWAS) are hypothesis-free studies that estimate the association between polymorphisms across the genome with a trait of interest. To increase power and to estimate the direct effects of these single-nucleotide polymorphisms (SNPs) on a trait GWAS are often conditioned on a covariate (such as body mass index or smoking status). This adjustment can introduce bias in the estimated effect of the SNP on the trait.

Time-of-day effects on physical performance and perceptual responses in Brazilian Jiu-Jitsu athletes.

This study investigated how the time of day affects physical performance and perceptual responses in Brazilian Jiu-Jitsu (BJJ) athletes. Given the significance of circadian rhythms on athletic capabilities, we aimed to determine whether performance variations occur across different times of the day (morning, 10:00-11:00h; afternoon, 14:00-15:00h; and evening, 18:00-19:00h) and if these effects differ by sex. In total, 23 BJJ athletes (9 females, 14 males) participated in this study.

The impact on productivity costs of reducing unemployment in patients with advanced breast cancer: A model estimation based on a Portuguese nationwide observational study.

This study aimed to characterize the employment status and work-related conditions of patients with advanced breast cancer (ABC) in Portugal and quantify the productivity costs of premature abandonment of the work market while evaluating strategies to promote employment. The analysis was based on a cumulative incidence model for estimation of ABC prevalence and on a cross-sectional study characterizing the employment status of patients with ABC. This study was conducted in Portuguese hospitals, between Nov2021-Dec2022 and included patients diagnosed with ABC for at least 6 months, aged 66 or less and consenting for a self-answered questionnaire regarding work status.

Automatic segmentation of cardiac structures can change the way we evaluate dose limits for radiotherapy in the left breast.

Purpose: Radiotherapy is a crucial part of breast cancer treatment. Precision in dose assessment is essential to minimize side effects. Traditionally, anatomical structures are delineated manually, a time-consuming process subject to variability.

The Effect of a Nature-Based Gel on Gingival Inflammation and the Proteomic Profile of Crevicular Fluid: A Randomized Clinical Trial.

Evidence has shown the clear positive effects of nature-based products on biofilm control and improved gingival health. However, most studies have used in vitro models, have tested single natural components, or have not evaluated proteomic changes after treatment. This double-blind, parallel, randomized, and controlled clinical trial evaluated the benefits of a nature-based gel in controlling gingival inflammation and its effects on the proteomic gingival crevicular fluid (GCF) profile.

Vaccination coverage according to race or skin color in children born in 2017-2018 in Natal, Rio Grande do Norte, Brazil: a population survey.

Objective: To analyze vaccination coverage up to 24 months of age according to race/ skin color in the 2017-2018 live birth cohort in Natal, Rio Grande do Norte, Brazil.

Methods: Population-based survey conducted in 2020 and 2021. Vaccination coverage up to 24 months of age was estimated according to administered, valid and timely doses.

Full vaccination coverage with valid doses among the 2017 and 2018 live birth cohort in the Southeast region of Brazil.

Objective: To analyze factors associated with full vaccination coverage with valid doses, in children from four state capitals and three other cities in Southeast Brazil.

Method: Analysis of a population survey conducted in 2020-2021, with a sample stratified according to socioeconomic levels of children born in 2017-2018, with data collected through photographic records of their vaccination cards. Odds ratios (OR) and 95% confidence intervals (95%CI) for full vaccination coverage were estimated based on the characteristics of the family, mother and child.

Measles, mumps and rubella vaccination coverage in capitals and interior region municipalities of Northeast Brazil: a household survey in a cohort of children born in 2017 and 2018.

Objective: To analyze measles, mumps, and rubella vaccination coverage among children up to 24 months old and factors associated with non-vaccination in a 2017-2018 live birth cohort, in state capitals and large interior region cities in Northeast Brazil.

Methods: Population-based survey analyzing vaccination coverage and sociodemographic factors through logistic regression.

Results: For 12,137 children, vaccination coverage was 79.

Evaluating causal associations of chronotype with pregnancy and perinatal outcomes and its interactions with insomnia and sleep duration: a mendelian randomization study.

Background: Observational studies suggested chronotype was associated with pregnancy and perinatal outcomes. Whether these associations are causal is unclear. Our aims are to use Mendelian randomization (MR) to explore (1) associations of evening preference with stillbirth, miscarriage, gestational diabetes, hypertensive disorders of pregnancy, perinatal depression, preterm birth and offspring birthweight; and (2) differences in associations of insomnia and sleep duration with those outcomes between chronotype preferences.

Genome-wide association studies and functional annotation of pre-weaning calf mortality and reproductive traits in Nellore cattle from experimental selection lines.

Background: Reproductive efficiency is crucial for the long-term economic sustainability of beef cattle production. Pregnancy loss and stillbirth are complex reproductive traits that do not yet have their genomic background fully understood, especially in zebu breeds (Bos taurus indicus). Hence, this study aimed to perform a genome-wide association study (GWAS) and functional annotation for conception success (CS), pregnancy loss (PL), stillbirth (SB), and pre-weaning calf mortality (PWM) in Nellore cattle.

Spinal antinociceptive effect of the PnTx4(5-5) peptide is possibly mediated by the NMDA autoreceptors.

Background: Medications currently used to treat pain are frequently associated with serious adverse effects and rapid development of tolerance. Thus, there is a need to develop more effective, and safer medicines for the population. Blocking NMDA receptors (NMDAR) has shown to be a promising target for the development of new drugs.

Over 400 food resources from Brazil: evidence-based records of wild edible mushrooms.

Many species of mushroom-forming fungi have been harvested in the wild and used for food and medicine for thousands of years. In Brazil, the knowledge of the diversity of wild edible mushrooms remains scattered and poorly studied. Based on new samples, bibliographic records revision, and searches through the GenBank, we recorded 409 species of wild edible mushrooms in Brazil, of which 350 can be safely consumed and 59 are edible but with conditions.

What challenges hinder the adoption of antimicrobial surface in the dental implant market?

Introduction: Implant failures resulting from peri-implant infections can have substantial consequences, underscoring the urgent need for effective strategies to prevent biofilm formation on implant surfaces. However, despite advancements in antimicrobial surface technologies, significant challenges persist in translating these innovations into clinically viable solutions.

Areas Covered: This article provides an overview of the limitations of current treatment protocols and explores the potential of antimicrobial surface treatments for controlling such infections.

Impact of SARS-CoV-2 variants on COVID-19 symptomatology and severity during five waves.

Background: SARS-CoV-2 variants have distinct features of transmissibility, infectivity, and aggressiveness that may cause different clinical manifestations. A better understanding of the disease presentation and progression could help to outline more precise preventive and treatment frameworks. This study describes the differences in COVID-19 presentation and outcomes across five variant waves.

Evaluation of Mart. (Bacuri Butter) and Biopolymers from the Puree of L. (Yellow Onion Bulb) for Wound Healing in Horses.

Skin injuries are common in the equine clinical practice, requiring effective treatment to support natural healing. Bacuri butter is gaining attention for its potential in wound healing and its anti-inflammatory, antimicrobial, and antioxidant properties. Natural polymers such as onion () bioplastics have been investigated for their potential as occlusive dressings and for tissue regeneration.

Tailoring magnesium-doped coatings for improving surface and biological properties of titanium-based dental implants.

Physicochemical modifications of biomaterials have been proposed to overcome bone integration impairment and microbial infections. The magnesium (Mg) incorporation on dental implant surfaces has shown positive results in bone-to-implant contact and in the reduction of microbial colonization. Here, we explored the potential of using different Mg precursors to synthesize coatings via plasma electrolytic oxidation (PEO) on commercially pure titanium (cpTi), aiming to optimize the surface and biological properties.