Zhong Xi Yi Jie He Xue Bao
February 2011
Objective: Methanol extract of whole plant of Amaranthus caudatus (MEAC) was screened for hepatoprotective potency against paracetamol (PCM)-induced liver damage in Wistar rats.
Methods: Rats of five groups were given sodium carboxy methyl cellulose, PCM, MEAC (200 and 400 mg/kg, respectively) plus PCM, and silymarin plus PCM, respectively. Fourteen days after administration, blood samples were collected for biochemical estimation, then animals were sacrificed and liver samples were collected, weighed and subjected for histopathological studies.