Comparison of fit and trueness of single-unit and short-span fixed dental restorations fabricated by additive and subtractive manufacturing-A systematic review and meta-analysis.

Objectives: Numerous studies have been conducted on the adaptation of dental restorations fabricated by additive (AM) and subtractive manufacturing (SM); however, the results are conflicting. This systematic review and meta-analysis aimed to evaluate the fit and trueness of fixed restorations made by AM compared to SM.

Data: Studies investigating internal fit, marginal fit, and trueness of fixed prostheses were involved.

Reference CAD-CAM Samples for Dental Shade Communication for Successful Aesthetic Outcome.

Purpose: The study aims to produce CAD-CAM reference samples for shade communication milled from the material of the restoration zirconia (ZrO2) and zirconia-reinforced lithium silicate (ZLS) and evaluate the color difference with the corresponding conventional Vita Classical (VC) shade tab. Furthermore, it aims to verify the color consistency of the materials.

Materials And Methods: Five-five samples were milled out of ZrO2 and ZLS in five different colors and their color parameters were compared with the corresponding VC tabs both visually and digitally.

Evaluation of the dimensional stability of 3D-printed dental casts.

Objective: The objective was to investigate the dimensional stability of different types of 3D printed dental models, and to measure the dimensional changes over time.

Methods: Four dental casts with different constructions were printed. The four types of models were as follows: hollow casts with 2.

Quantitative examination of factors influencing the colour reproduction ability of lithium disilicate glass-ceramics.

Background: Effects of ceramic translucency, layer thickness, and substrate colour on the shade of lithium disilicate glass-ceramic restorations proved to be significant in several studies, however, quantitative, numerical results on the relationship between the colour difference and these parameters are still lacking. The purpose of this in vitro study was to quantitatively determine how the colour reproduction ability of a lithium disilicate glass-ceramic is affected by its translucency, layer thickness, and substrate colour.

Methods: Ceramic samples were prepared from A2 shade IPS e.

Evaluating the influence of palate scanning on the accuracy of complete-arch digital impressions-An in vitro study.

Objectives: To assess the impact of including the palate and the number of images recorded during intraoral digital scanning procedure on the accuracy of complete arch scans.

Methods: An experienced operator conducted 40 digital scans of a 3D printed maxillary model and divided them into two groups: 20 with inclusion of the palate (PAL) and 20 without (NPAL). Each set of scans was performed using an intraoral scanner (IOS) (Trios 5; 3Shape A/S; Copenhagen, Denmark).

Trueness of five different 3D printing systems including budget- and professional-grade printers: An In vitro study.

Problem: Several types of 3D printers with different techniques and prices are available on the market. However, results in the literature are inconsistent, and there is no comprehensive agreement on the accuracy of 3D printers of different price categories for dental applications.

Aim: This study aimed to investigate the accuracy of five different 3D printing systems, including a comparison of budget- and higher-end 3D printing systems, according to a standardized production and evaluation protocol.

Comparative analysis of surgical and prosthetic rehabilitation in maxillectomy: A systematic review and meta-analysis on quality-of-life scores and objective speech and masticatory measurements.

Statement Of Problem: Patients with oro-antral communication, whether from trauma, disease, or congenital anomalies, have options for surgical reconstruction or prosthetic obturation, but guiding interdisciplinary protocols are lacking.

Purpose: The purpose of this systematic review and meta-analysis was to compare surgical reconstruction and prosthetic obturation, identifying correlations with baseline characteristics to determine the most effective approach for specific patients.

Material And Methods: A systematic search was conducted in 4 databases.

Combined Casein Phosphopeptide-Amorphous Calcium Phosphate and Fluoride Is Not Superior to Fluoride Alone in Early Carious Lesions: A Meta-Analysis.

There is a growing need for effective methods in the management of early stage carious lesions. Therefore, the aim of this study was to evaluate the effect of combined casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride on white spot lesions (WSLs) compared to fluoride-only interventions. This meta-analysis was performed according to PRISMA guidelines and registered in PROSPERO (CRD42021286245).

The effect of generation change on the accuracy of full arch digital impressions.

Purpose: This study is aimed to evaluate the effect of generation change on accuracy of IOSs on full-arch scans and the inter-operator reliability.

Methods: In this study, 6 different IOS were tested: 3Shape Trios 3 (20.1.

Evaluation of the accuracy of intraoral scanners for complete-arch scanning: A systematic review and network meta-analysis.

Objectives: This network meta-analysis (NMA) aimed to compare the complete-arch scanning accuracy of different intraoral scanners (IOSs) to that of reference standard tessellation language (STL) files.

Data: Studies comparing the trueness and precision of IOS STL files with those of reference STL scans for different arch types (dentate, edentulous, completely edentulous with implants, and partially edentulous with implants) were included in this study.

Sources: An electronic search of five databases restricted to the English Language was conducted in October 2021.

Business Risk Mitigation in the Development Process of New Monoclonal Antibody Drug Conjugates for Cancer Treatment.

Recent developments aim to extend the cytotoxic effect and therapeutic window of mAbs by constructing antibody-drug conjugates (ADCs), in which the targeting moiety is the mAb that is linked to a highly toxic drug. According to a report from mid of last year, the global ADCs market accounted for USD 1387 million in 2016 and was worth USD 7.82 billion in 2022.

Effect of thickness, translucency, and substrates on the masking ability of a polymer-infiltrated ceramic-network material.

Objective: The aim of this in vitro study is to evaluate the masking ability of polymer-infiltrated ceramic-network materials (PICN) with different translucencies and thicknesses on multiple types of substrates.

Materials And Methods: Ceramic samples were prepared of VITA ENAMIC blocks in two different translucencies (2M2-T, 2M2-HT) in a thickness range of 0.5-2.

Current status of optical scanning in facial prosthetics: A systematic review and meta-analysis.

Purpose To assess the accuracy of scanning technologies for constructing facial prostheses on human faces.Study selection Our systematic search was performed on five databases. Studies reporting on human volunteers (P) whose faces were scanned with a scanning technology were eligible.

Additional splint therapy has no superiority in myogenic temporomandibular disorders: A systematic review and meta-analysis of randomized controlled trials.

Purpose Temporomandibular disorders (TMDs) are frequent stomatological disorders. However, their treatment is controversial. Therefore, we compared the efficacy of combination therapy (splint therapy along with physiotherapy, manual therapy, and counseling) with physiotherapy, manual therapy, and counseling alone.

Comparison of the learning curve of intraoral scanning with two different intraoral scanners based on scanning time.

Background: The appearance of intraoral scanners (IOSs) in dental offices was an important milestones for the digital innovations in dentistry. Knowing the learning curve for intraoral scanning is crucial, because it can serve as a guideline for clinicians before buying a new IOS. The aim of the present in vivo study was to determine the learning curve required by dental students for intraoral scanning with the 3Shape Trios 4 IOS and the CEREC Primescan IOS, based on scanning time.

User Experience of Intraoral Scanners in Dentistry: Transnational Questionnaire Study.

Introduction: Intraoral scanners (IOS) are continuing to gain popularity in clinical dentistry, replacing the traditional impression-taking and related technology. Despite their increasing importance, there are few data on the utility and usage of IOS amongst dentists. This study investigates the user experience of IOS technology as well as the perceived quality of a variety of IOS used by dental clinicians worldwide.

Clear guidance to select the most accurate technologies for 3D printing dental models - A network meta-analysis.

Objectives: Thus far, the findings of numerous studies conducted on the accuracy of three-dimensional (3D) printed dental models are conflicting. Therefore, the aim of the network meta-analysis (NMA) is to determine the accuracy of 3D printed dental models compared with digital reference models.

Data: Studies comparing the accuracy of 3D printed full-arch dental models manufactured using different printing techniques to initial STL files were included.

The impact of software updates on accuracy of intraoral scanners.

Background: Digital workflow is showing an increasing tendency in everyday dentistry. Accuracy is essential during digital dental workflows for all indication areas. The present study aimed to evaluate the effect of software updates on the accuracy of intraoral scanner (IOS) devices.

Digital intraoral scanner devices: a validation study based on common evaluation criteria.

Background: The evolution of intraoral scanners (IOSs) is rapid, and new IOSs appear on the market with different properties depending on the manufacturers. There is no uniform rating system based on a defined set of aspects that has reported in the literature that can be used to compare these devices. This validation study aimed to compare different IOSs based on objective and comprehensive parameters.

Acalabrutinib and its use in the treatment of chronic lymphocytic leukemia.

Bruton's tyrosine kinase inhibitors have changed the treatment landscape for chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL) and lymphoplasmacytic lymphoma dramatically. In 2019, acalabrutinib was approved by the US FDA for the treatment of treatment-naive and relapsed/refractory CLL and MCL. Acalabrutinib monotherapy was found to be effective and safe in CLL patients.

Comparing the effectiveness of shade measurement by intraoral scanner, digital spectrophotometer, and visual shade assessment.

Objective: Trios3 (3Shape, Denmark) intraoral scanner is complete with a tooth shade measurement function, but there is limited information about its efficacy. This in vivo study aimed to evaluate this function in relation to visual and spectrophotometric shade determination.

Materials And Methods: Ten dental students from Semmelweis University determined tooth shade for 10 volunteers using Vita A1-D4 (VC) and Vita Linearguide 3D-Master (LG) guides, Vita Easyshade spectrophotometer (ES) and Trios 3 intraoral scanner (TR).