Publications by authors named "Borate S"
Article Synopsis
- The study aimed to assess the effectiveness of a new drug combination for treating oral submucous fibrosis (OSMF) in patients across different severity grades.
- A total of 89 patients were analyzed retrospectively over 12 months, showing significant improvements in clinical parameters like mouth opening and reduction of burning sensation following treatment.
- Results indicated that the new drug combination was effective in enhancing patients' symptoms across all grades of OSMF, with sustained benefits observed throughout the follow-up period.
Article Synopsis
- BTK inhibitors show promising efficacy for treating chronic lymphocytic leukemia and B-cell lymphomas, but their use can lead to infections, impacting patient outcomes.
- A systematic review and meta-analysis of 12 studies revealed a 55% increased risk of upper respiratory tract infections (URTIs) among patients on BTK inhibitors, although more severe infections like pneumonia did not show statistically significant elevation in risk.
- The study underscores the importance of monitoring and preventative measures for infections in patients receiving BTK inhibitor therapy to ensure better management of their health.
This scoping review aimed to review and summarize the evidence related to the attitudes toward human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP)/postexposure prophylaxis (PEP) among people at risk of HIV, health care workers (HCWs), and the general population in India. A literature search of PubMed, Embase, Scopus, and PsycINFO was conducted from January 1, 2002, to February 1, 2024. The search field contained a combination of keywords and MeSH terms such as: HIV, PrEP, PEP knowledge, awareness, willingness, and practice.
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- Single-site copper-based catalysts are effective for various reactions but face issues like deactivation due to sintering at high temperatures, which can alter their structure irreversibly.
- The study presents zeolite-based copper catalysts that can revert agglomerated copper oxide back to single-site structures through an oxidative process at 550 °C.
- Dynamic changes in the structure and oxidation state of single-site copper can be manipulated to enhance active site creation while preventing deactivation, potentially broadening their application in different reactions.
Objective: Improving solubility and bioavailability of albendazole (ALB).
Significance: ALB is a broad-spectrum anthelminthic BCS class II drug with aqueous solubility of solubility of 4.1 mg/l at 25 °C and oral bioavailability of <5%.
The objective of present study was to evaluate the effect of processing methods and sintering condition on matrix formation and subsequent drug release from wax matrix tablets for controlled release. Ketorolac tromethamine and compritol were processed with appropriate diluent using either dry blending, spray drying, partial melt granulation or melt granulation.The tablets were then sintered at 80 degrees .
View Article and Find Full Text PDFBackground: Various approaches have been used to retain the dosage form in stomach as a way of increasing the gastric residence time, including floatation systems; high-density systems; mucoadhesive systems; magnetic systems; unfoldable, extensible, or swellable systems; and superporous hydrogel systems.
Aim: The objective of this study was to prepare and evaluate floating microspheres of rosiglitazone maleate for the prolongation of gastric residence time.
Method: The microspheres were prepared by solvent diffusion-evaporation method using ethyl cellulose and hydroxypropylmethylcellulose.
The present research studied the effect of sintering technique in the development of a controlled release formulation for ketorolac tromethamine. The method consisted of mixing drug and wax powder (Compritol 888 ATO) along with lactose as diluent and talc as lubricant followed by direct compression at room temperature. The compressed fluffy matrices were kept at 80 degrees C for 1, 2, and 3 h for sintering.
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