Refractive outcomes for secondary sutureless posterior chamber lens implantation: sutureless scleral fixating lens Carlevale® versus retropupillary iris-claw lens Artisan®.

Purpose: To compare refractive outcomes of the foldable intraocular lens sutureless scleral fixated sutureless (Carlevale® FIL-SSF) with the iris-claw lens (Artisan®).

Methods: This retrospective study included consecutive patients who underwent a FIL-SSF implantation or an iris-claw implantation between January 2020 and November 2022 in the ophthalmology departments of Hospices Civils de Lyon (France).

Results: A total of 271 eyes from 265 patients were included: 96 eyes in the FIL-SSF group and 175 eyes in the iris-claw group.

A Viral-Encoded Homologue of IPS-1 Modulates Innate Immune Signaling During KSHV Lytic Replication.

Modulation of innate immunity is critical for virus persistence in a host. In particular, viral-encoded disruption of type I interferon, a major antiviral cytokine induced to fight viral infection, is a key component in the repertoire of viral pathogenicity genes. We have identified a previously undescribed open reading frame within the Kaposi's sarcoma-associated herpesvirus (KSHV) genome that encodes a homologue of the human IPS-1 (also referred to as MAVS) protein that we have termed viral-IPS-1 (v-IPS-1).

Correction: Inflation of wood resources in European forests: The footprints of a big-bang.

[This corrects the article DOI: 10.1371/journal.pone.

FIL SSF intraocular lens opacification after gas tamponade: A case series.

Purpose: To report three cases of postoperative opacification of sutureless scleral-fixed hydrophilic intraocular lens (FIL SSF IOL, Soleko, Italy) after gas tamponade. Two cases occurred after pars plana vitrectomy and one case after Descemet membrane endothelial keratoplasty.

Case Report: Two diabetic patients underwent a FIL SSF IOL implantation after posterior capsular rupture during cataract surgery.

The Property Rights Index (PRIF) can be used worldwide to compare different forest governance systems.

The bundle of forest landowners' rights largely varies from one jurisdiction to another. On a global scale, the diversity of forest management regime and property rights systems is such that finding comprehensive and standardised approaches for governance analysis purposes is a challenging task. This paper explores the use of the Property Rights Index for Forestry (PRIF) as an analytical tool based on five rights domains (access, withdrawal, management, exclusion, and alienation) to assess how regulatory frameworks impact the owners' forest property rights.

Inflation of wood resources in European forests: The footprints of a big-bang.

The current increase in European forest resources forms a singularity across the globe. Whether this trend will persist, and how biological and economic trends feature it form crucial issues to green economy challenges and C sequestration. The present screening of Forest Europe 2015 statistics explored the features, inertia and limits of this expansion, and its relationships with countries' development, forest management and trade, intense in this area of the world.

Diffuse sunlight and cosmic rays: Missing pieces of the forest growth change attribution puzzle?

Forest growth changes have been a matter of intense research efforts since the 1980s. Owing to the variety of their environmental causes - mainly atmospheric CO increase, atmospheric N deposition, changes in temperature and water availability, and their interactions - their interpretation has remained challenging. Recent isolated researches suggest further effects of neglected environmental factors, namely changes in the diffuse fraction of light, more efficient to photosynthesis, and galactic cosmic rays (GCR), both emphasized in this Discussion paper.

Recent growth trends of conifers across Western Europe are controlled by thermal and water constraints and favored by forest heterogeneity.

Tree growing conditions are changing rapidly in the face of climate change. Capturing tree-growth response to such changes across environmental contexts and tree species calls for a continuous forest monitoring over space. Based on >10,000 tree-ring measurements sampled across the systematic grid of the continuous French national forest inventory (NFI) over the 2006-2016 period, we evaluated the radial growth trends of eight conifer tree species prevalent in European forests across their native and introduced ranges and various bioclimatic contexts (n = 16 forest systems).

Background mortality drivers of European tree species: climate change matters.

Increases in tree mortality rates have been highlighted in different biomes over the past decades. However, disentangling the effects of climate change on the temporal increase in tree mortality from those of management and forest dynamics remains a challenge. Using a modelling approach taking tree and stand characteristics into account, we sought to evaluate the impact of climate change on background mortality for the most common European tree species.

Development of a clinical prediction score for detection of suspected cases of equine grass sickness (dysautonomia) in France.

Equine grass sickness (EGS) (equine dysautonomia) is a neurodegenerative condition of grazing equines. Pre-mortem diagnosis of EGS is a challenge for practitioners as definitive diagnosis requires ileal/myenteric lymph node biopsies. This study aimed to develop a clinical score that could be used by practitioners to improve the detection of acute or subacute EGS cases in the field.

Disruption of Type I Interferon Induction by HIV Infection of T Cells.

Our main objective of this study was to determine how Human Immunodeficiency Virus (HIV) avoids induction of the antiviral Type I Interferon (IFN) system. To limit viral infection, the innate immune system produces important antiviral cytokines such as the IFN. IFN set up a critical roadblock to virus infection by limiting further replication of a virus.

Stand density, tree social status and water stress influence allocation in height and diameter growth of Quercus petraea (Liebl.).

Even-aged forest stands are competitive communities where competition for light gives advantages to tall individuals, thereby inducing a race for height. These same individuals must however balance this competitive advantage with height-related mechanical and hydraulic risks. These phenomena may induce variations in height-diameter growth relationships, with primary dependences on stand density and tree social status as proxies for competition pressure and access to light, and on availability of local environmental resources, including water.

Value of occupational medicine board certification.

Objective: To assess the impact of occupational medicine board certification and career stage on practice characteristics.

Methods: Two hundred sixty occupational medicine physicians completed a questionnaire and 25 activity log descriptions about 72 items in 9 major domains. For each item, the percentage of activities involving the item and the percentage of physicians conducting the item at least once were calculated.

Career paths in occupational medicine.

Objective: To describe career path patterns for occupational medicine (OM) physicians.

Methods: A convenience sample of 129 occupational physicians described work activities and locations at several career points up to 20 years ago, first OM position, and 10 years after expectations.

Results: Clinical activities were important throughout (eg, 41% and 46% of occupational physicians reported frequently treating patients 20 years ago and currently).

Fagus sylvatica trunk epicormics in relation to primary and secondary growth.

Background And Aims: European beech epicormics have received far less attention than epicormics of other species, especially sessile oak. However, previous work on beech has demonstrated that there is a negative effect of radial growth on trunk sprouting, while more recent investigations on sessile oak proved a strong positive influence of the presence of epicormics. The aims of this study were, first, to make a general quantification of the epicormics present along beech stems and, secondly, to test the effects of both radial growth and epicormic frequency on sprouting.

Cambial activity related to tree size in a mature silver-fir plantation.

Background And Aims: Our knowledge about the influences of environmental factors on tree growth is principally based on the study of dominant trees. However, tree social status may influence intra-annual dynamics of growth, leading to differential responses to environmental conditions. The aim was to determine whether within-stand differences in stem diameters of trees belonging to different crown classes resulted from variations in the length of the growing period or in the rate of cell production.

Occupational medicine practice: activities and skills of a national sample.

Objective: To characterize activities and skills of occupational physicians using work diaries.

Methods: A total of 260 occupational physicians from a national sample provided task/skill descriptions at approximately 25 specific times. The average percentage of activity samples using a skill and the interquartile range expressed results.

Occupational medicine practice: one specialty or three?

Objective: To characterize education, practice, and skills of occupational physicians and to evaluate subgroups within the profession.

Methods: The data for the baseline surveys of the occupational medicine practice research project were collected for a national sample of occupational physicians using paper or on-line instruments. Three subgroups were defined a priori-injury care, clinical specialist, and management/population.

Analysis of dansyl derivatives of di- and polyamines in mouse brain, human serum and duodenal biopsy specimens by high-performance liquid chromatography on a standard reversed-phase column.

The concentrations of putrescine, spermine and spermidine were measured in human serum, children's duodenal biopsy specimens and mouse brain homogenates by high-performance liquid chromatography. The chromatographic analysis was performed on dansyl derivatives of the polyamines using a reverse-phase system with an ion-pairing retention mechanism (heptane sulphonate). Capacity factors were determined at different concentrations of acetonitrile.

High-yield synthesis of a [3H]ethylenediamine ditetrodotoxin derivative.

[3H]Tetrodotoxin [( 3H]TTX) and a [3H]ethylenediamine derivative of TTX are the most widely used ligands for the study of the Na channel. The former ligand presents a low specific radioactivity (1 Ci/mmol) while the latter is highly labeled (30 Ci/mmol). However, its two-step synthesis, i.

Determination of thiamine and thiamine phosphates in excitable tissues as thiochrome derivatives by reversed-phase high-performance liquid chromatography on octadecyl silica.

The analysis of thiamine and thiamine phosphates by high-performance liquid chromatography owes its high sensitivity to the fluorescent derivatives or thiochromes obtained by chemical oxidation in alkaline medium. The possibility of performing precolumn oxidation with potassium ferricyanide instead of using the hazardous cyanogen bromide has been investigated. The derivatization step has been optimized with respect to the following parameters: concentration of alkali and oxidant, presence of methanol and stability of the thiochromes .

Binding of [3H]ethylenediamine di-tetrodotoxin to its solubilized receptor from excitable tissues. Binding measurements by rapid gel-filtration and receptor stabilization by phosphatidylcholine.

The molecular study of bioelectrogenesis requires the purification of the membrane proteins involved in the Na-channel electrical activity. This complex biological structure contains various binding sites for different classes of neurotoxins. Labelled forms of the blocking agent, tetrodotoxin, are used to identified and quantified the solubilized membrane proteins during the purification.

Subcellular fractionation of Trypanosoma brucei bloodstream forms with special reference to hydrolases.

Bloodstream forms of Trypanosoma brucei have been screened for the presence of enzymes that could serve as markers for the plasma membrane, flagellar pocket, lysosomes, endoplasmic reticulum and Golgi apparatus in order to study the subcellular organization of the digestive system of the parasite. Acetylesterase, acid DNase, acid phosphatase, acid phosphodiesterase, acid proteinase, acid RNase, alanine aminotransferase, galactosyl transferase, alpha-glucosidase, inosine diphosphatase and alpha-mannosidase were partially characterized and their assays optimized for pH-dependent activity, linearity of reaction with respect to incubation time and enzyme concentration, and the effect of inhibitors and activators. The association of these enzymes with particulate material and the presence of structural latency were investigated.