Improved neurodevelopmental outcomes for extremely low birth weight infants in 2000-2002.

Background: Neurodevelopmental impairment of extremely low birth weight infants increased in the 1990s. Modern therapeutic changes may have influenced more recent neonatal outcomes.

Objective: We sought to compare neonatal therapies and outcomes among all extremely low birth weight infants born in 2000-2002 (period III) to 2 previous periods: 1982-1989 (period I) and 1990-1999 (period II).

Adverse events associated with neonatal exchange transfusion in the 1990s.

Objective: To determine the rates of adverse events associated with neonatal exchange transfusions performed for hyperbilirubinemia.

Study Design: Retrospective chart review of 55 neonates who underwent 66 exchange transfusions at two perinatal centers in Cleveland between 1992 and 2002. Demographic data, causes of jaundice, details of exchange method, and adverse events occurring within one week of exchange were recorded.