The effect of weight loss interventions for obesity on fertility and pregnancy outcomes: A systematic review and meta-analysis.

Background: Weight loss could improve fertility, perhaps by reducing insulin resistance.

Objectives: To assess the effect of weight loss interventions on fertility in women with obesity not recruited because of known infertility.

Search Strategy: Three databases during 1966-2020, trial registry.

Fractures in Adults After Weight Loss from Bariatric Surgery and Weight Management Programs for Obesity: Systematic Review and Meta-analysis.

Background: Weight loss interventions for obesity, such as bariatric surgery, are associated with reductions in bone mineral density and may increase the risk of fractures. We undertook a systematic review and meta-analysis of bariatric surgery and lifestyle weight management programs (WMPs) with fracture outcomes.

Methods: We searched MEDLINE, Embase, the Cochrane Central Register of Controlled Trials from 1966 to 2018, and our trial registry of WMP randomized controlled trials (RCTs).