Comparison of analgesic and tissue effects of subcutaneous perineural injection of liposomal bupivacaine and bupivacaine hydrochloride in horses with forelimb lameness induced via circumferential clamp.

Objective: To evaluate the analgesic and tissue effects of liposomal bupivacaine administered SC as an abaxial sesamoid nerve block in horses with experimentally induced lameness.

Animals: 6 healthy mature light-breed horses.

Procedures: In a randomized crossover study, a circumferential hoof clamp was applied to a forelimb to induce reversible lameness.

The effect of intravenous maropitant on blood pressure in healthy awake and anesthetized dogs.

Objective: To evaluate the effects of intravenous maropitant on arterial blood pressure in healthy dogs while awake and under general anesthesia.

Design: Experimental crossover study.

Animals: Eight healthy adult Beagle dogs.

Effects of 2% lidocaine hydrochloride solution as a coinduction agent with propofol on cardiopulmonary variables and administered propofol doses in healthy dogs premedicated with hydromorphone hydrochloride and acepromazine maleate.

Objective: To evaluate the effects of lidocaine as a coinduction agent with propofol on cardiopulmonary variables and administered propofol doses in healthy dogs premedicated with hydromorphone hydrochloride and acepromazine maleate and anesthetized with isoflurane.

Animals: 40 client-owned dogs (American Society of Anesthesiologists physical status classification I or II and age ≥ 6 months) scheduled to undergo anesthesia for elective procedures.

Procedures: In a randomized, blinded, controlled clinical trial, dogs received 2% lidocaine hydrochloride solution (2.

Assessment of Dog Owner Concern Regarding Peri-operative Nausea and Vomiting and Willingness to Pay for Anti-emetic Treatment.

The objective of this study was to assess dog owners' concern regarding peri-operative nausea and vomiting, and their willingness to pay for treatment. Descriptive survey. A survey was administered to 104 dog owning clients with non-emergent surgical (52) or non-surgical (52) appointments at a University teaching hospital.

Spotlight on the perioperative use of maropitant citrate.

Neurokinin-1 (NK-1) receptors are present in both the central nervous system and peripheral tissues. Substance P (SP) is the major ligand and is involved in multiple processes including pain transmission, vasodilation, modulation of the inflammatory response, as well as the sensory neuronal transmission involved in stress, anxiety, and emesis. The involvement of NK-1 and SP in the vomiting reflex has led to the development of NK-1 antagonists to prevent and treat vomiting in human and veterinary medicine.

Effects of administration of a synthetic low molecular weight/low molar substitution hydroxyethyl starch solution in healthy neonatal foals.

This study compared the effects of IV administration of isotonic fluid therapy and colloidal fluid therapy in healthy neonatal foals. Fifteen healthy neonatal foals were used in a randomized blinded prospective clinical study. Foals were randomly assigned to receive a bolus of 20 mL/kg of tetrastarch (TES) or balanced crystalloid solution.

Effect of dosing interval on efficacy of maropitant for prevention of hydromorphone-induced vomiting and signs of nausea in dogs.

Objective: To evaluate the effect of dosing interval on the efficacy of maropitant for prevention of opioid-induced vomiting and signs of nausea in dogs.

Design: Randomized prospective clinical study.

Animals: 50 client-owned dogs that underwent an elective surgical procedure.

Efficacy of orally administered maropitant citrate in preventing vomiting associated with hydromorphone administration in dogs.

Objective: To evaluate the effectiveness of orally administered maropitant citrate in preventing vomiting after hydromorphone hydrochloride administration in dogs.

Design: Randomized, blinded, prospective clinical study.

Animals: 40 dogs with American Society of Anesthesiologists status of I or II, > 6 months of age, and weighing between 24 and 58.

Efficacy of maropitant in preventing vomiting in dogs premedicated with hydromorphone.

Objective: The goal of this study was to evaluate the effectiveness of maropitant (Cerenia(®)) in preventing vomiting after premedication with hydromorphone.

Study Design: Randomized, blinded, prospective clinical study.

Animals: Eighteen dogs ASA I/II admitted for elective orthopedic surgical procedures.

Physiologic effects of nasopharyngeal administration of supplemental oxygen at various flow rates in healthy neonatal foals.

Objective: To evaluate the effects of various flow rates of oxygen administered via 1 or 2 nasal cannulae on the fraction of inspired oxygen concentration (FIO2) and other arterial blood gas variables in healthy neonatal foals.

Animals: 9 healthy neonatal (3- to 4-day-old) foals.

Procedures: In each foal, a nasal cannula was introduced into each naris and passed into the nasopharynx to the level of the medial canthus of each eye; oxygen was administered at 4 flow rates through either 1 or both cannulae (8 treatments/foal).

Vascular-mineral spatial correlation in the calcifying turkey leg tendon.

Certain avian tendons are known to mineralize normally in a gender-related manner. These tendons have unique properties, as well as several features common to calcifying cartilage and bone in other vertebrate species. In cartilage and bone, mineralization has been associated with a vascular and microvascular origin, but such a relationship has not been established in the avian tendon.