Therapeutic Potential of Flavonoid Derivatives for Certain Neglected Tropical Diseases.

Background: Neglected tropical diseases (NTDs) are infectious diseases that mostly affect people living in tropical and subtropical regions, especially in impoverished areas. Ubiquitously found in plants, flavonoids are a group of compounds that have been reported to exhibit a wide range of biological activities against parasites (Leishmania sp., Trypanosoma cruzi, Trypanosoma brucei, Brugia malayi, etc.

In Situ Stabilisation of Silver Nanoparticles at Chitosan-Functionalised Graphene Oxide for Reduction of 2,4-Dinitrophenol in Water.

This investigation reports the in situ growth of silver nanoparticles onto covalently bonded graphene oxide-chitosan, which serve as supported nanocatalysts for the NaBH reduction of 2,4-dinitrophenol in aqueous systems. Fumaryl chloride reacted with chitosan in an acidic environment to yield a tailored polymeric material. The latter was, in turn, treated with the pre-synthesised graphene oxide sheets under acidic conditions to generate the GO-functionalised membrane (GO-FL-CS).