Efficacy of topical drug application to manage in-office bleaching sensitivity: a systematic review and meta-analysis of randomized clinical trials.

Objectives: To answer whether the topical drug application can reduce in-office tooth bleaching sensitivity without impairing the color change.

Materials And Methods: This review was registered on PROSPERO (CRD42024524171). Two reviewers screened PubMed, Web of Science, Scopus, Embase, and clinicaltrials.

Are bodybuilding and cross-training practices dangerous for promoting orofacial injuries? A scoping review.

Bodybuilding and cross-training exercises bring health benefits. However, orofacial injuries can occur during practice. This study aimed to map, analyze, interpret, and synthesize data from studies on the main orofacial injuries resulting from bodybuilding and cross-training practices.

Can carbamide peroxide be as effective as hydrogen peroxide for in-office tooth bleaching and cause less sensitivity? A systematic review.

This study aimed to answer the question through a systematic review: Can carbamide peroxide be as effective as hydrogen peroxide and cause less in-office bleaching sensitivity? A literature survey was performed in PubMed/MEDLINE, Embase, Scopus, ISI Web of Science, and gray literature. Primary clinical trials that compared the efficacy or the in-office bleaching sensitivity between carbamide and hydrogen peroxides were included. The risk of bias was evaluated using the RoB2.

Addition of substances to reduce the erosive potential of acidic beverages to tooth enamel: A scoping review.

Objective: This scoping review aimed (1) to map, analyse, interpret and synthesize data from in situ studies on which substances were added to acidic beverages to reduce the erosive potential on tooth enamel and (2) to establish the level of evidence of the effectiveness of adding substances to acidic beverages to reduce the erosive potential on tooth enamel.

Design: This is a scoping review, according to the methods from the Joanna Briggs Institute and PRISMA-ScR, with high-sensitivity searches in the databases PubMed (MEDLINE), Virtual Health Library, Embase (Elsevier), Scopus (Elsevier), Web of Science and ScienceDirect (Elsevier). In situ studies published in English until December 2022 were included.

Are polywave light-emitting diodes more effective than monowave ones in the photoactivation of resin-based materials containing alternative photoinitiators? A systematic review.

Objective: This systematic review aimed to analyze if using polywave light-emitting diodes (LED) to photoactivate resin-based materials (resin composites, adhesive systems, and resin cements) containing alternative photoinitiators provide better physicochemical properties than monowave ones.

Material And Methods: Inclusion criteria were in vitro studies that evaluated the degree of conversion, microhardness and flexural strength in resin-based materials containing alternative photoinitiators and light-activated with mono and polywave LEDs. Exclusion criteria were studies that evaluated the physicochemical properties of composites through any material interposed between the LED and the resin composite and studies that exclusively compared different modes and/or light activation times.

Functional Ability of Dental Materials After Inclusion of Nanocarriers Containing Functional Substances: A Systematic Review.

Background: Nanocarriers are nanoparticles used to transport functional substances.

Objective: This study aimed to perform a systematic review analyzing the functional ability of dental materials after the inclusion of nanocarriers containing functional substances.

Materials And Methods: We searched PubMed, Web of Science, EMBASE, SciELO, and Science Direct from (02/03/21) to (02/06/21) without restriction on the year of publication.

Direct and semi-direct resin composite restoration in large cavity preparations: analysis of dentin bond strength stability and bottom/top microhardness ratio in a cavity model.

To evaluate the influence of the restorative approach and aging time on dentin bond strength (BS), failure mode (FM), and bottom/top microhardness ratio (B/T) in a large dentin cavity model. A total of 102 bovine incisors were used to produce models of conical dentin cavities (4.0 mm thickness × 4.

Can sterilization methods influence surface properties of resin composites? A purpose for previewing bias in laboratory bacterial adhesion tests.

This study aimed to evaluate the influence of sterilization methods on conventional and bulk-fill resin composites' (BFRCs) surface properties in an attempt to preview bias in laboratory bacterial adhesion tests. Two regular viscosity conventional resin composites [Filtek Z350 XT™ (Z350) and IPS Empress Direct™ (ED)] and two regular viscosity BFRCs [Filtek Bulk Fill™ (FILT) and Tetric N-Ceram Bulk Fill IVA™ (TBF)] were used. The materials were characterized by Scanning Electron Microscopy (SEM), surface roughness (SR), and wettability (W) after sterilization with hydrogen peroxide gas plasma (HPGP) and steam sterilization (SS).

Effects of ionizing radiation on surface properties of current restorative dental materials.

To investigate the impact of radiotherapy on surface properties of restorative dental materials. A conventional resin composite-CRC (Aura Enamel), a bulk-fill resin composite-BFRC (Aura Bulk-fill), a conventional glass ionomer cement-CGIC (Riva self cure), and a resin-modified glass ionomer cement-RMGIC (Riva light cure) were tested. Forty disc-shaped samples from each material (8 mm diameter × 2 mm thickness) (n = 10) were produced according to manufacturer directions and then stored in water distilled for 24 h.

A comprehensive review of the antibacterial activity of dimethylaminohexadecyl methacrylate (DMAHDM) and its influence on mechanical properties of resin-based dental materials.

The repetitive restorative cycle should be avoided, aiming at the smallest number of restorations' replacements to ensure greater tooth longevity. Antibacterial materials associated with the control of caries etiological factors can help improve restoration's durability. This review aimed to analyze the results of studies that added Dimethylaminohexadecyl methacrylate (DMAHDM), an antibacterial monomer, to restorative materials.

The combined use of systemic analgesic/anti-inflammatory drugs and a bioactive topical desensitizer for reduced in-office bleaching sensitivity without jeopardizing the hydrogen peroxide efficacy: a randomized, triple blinded, split-mouth clinical trial.

Objective: To evaluate the effect of combined systemic administration of paracetamol 500 mg/codeine phosphate 30 mg (PACO) and postoperative topical application of a bioactive desensitizer on in-office bleaching sensitivity and tooth color change.

Materials And Methods: A randomized, triple-blind, split-mouth clinical trial was conducted. Forty volunteers ingested PACO (n = 20) or placebo (PLA) (n = 20).

Influence of exposure to phosphoric and polyacrylic acids on selected microscopic and physical/chemical properties of calcium hydroxide cements.

Purpose: This study aimed to evaluate if the contact of calcium hydroxide cements with polyacrylic and phosphoric acids would alter selected microscopic and physical and chemical properties.

Materials And Methods: Chemically activated (Hydro C and Dycal Advanced Formula II) and resin-modified photoactivated (Ultra-blend Plus) calcium hydroxide cements were examined after exposure to the following different strategies: contact with no substance (control group); rinsing with water and drying; contact with polyacrylic acid, rinsing with water, and drying; and contact with phosphoric acid, rinsing with water, and drying. Surface morphology, determined by scanning electron microscopy (SEM), water sorption and solubility, and the release of hydroxyl ions were evaluated.

Relationship of Porphyromonas gingivalis and Alzheimer's disease: a systematic review of pre-clinical studies.

Objectives: This study aimed to analyze the following PICO question: Are animals infected with Porphyromonas gingivalis (P. gingivalis) or bacterial lipopolysaccharide (Pg-LPS) more affected by neurodegeneration, similar to the pathogenesis generated by Alzheimer's disease (AD), compared with non-infected animals?

Methods: Databases PubMed, Lilacs, SciELO, Science Direct, Scopus, Web of Science, and Cochrane were searched for pre-clinical in vivo studies in which mice were infected with P. gingivalis or received Pg-LPS, in order to assess the brain tissue and cognitive impairment.

Bonding performance and mechanical properties of flowable bulk-fill and traditional composites in high c-factor cavity models.

Objectives: The aim of this study is to evaluate bond strength (BS), shrinkage stress (SS), flexural strength (FS), and elastic modulus (E) of three flowable bulk fill in comparison with conventional composites.

Materials And Methods: Three bulk fill (Filtek Bulk Fill Flow, Surefil SDR, X-tra Base) and three conventional composites (Filtek Z250 XT, Grandioso, Dentsply TPH3) were used. For BS, conical cavities ( = 10) were prepared in bovine dentine and restored with materials and were analyzed through push-out test in a universal testing machine (UTM).

Impact of additional polishing method on physical, micromorphological, and microtopographical properties of conventional composites and bulk fill.

The objective of this study was to evaluate the surface roughness (SR), contact angle (CA), depth distribution of the charge particles (DDCP), mapping of chemical elements, 3D microtopography (3DM), and the micromorphology of the composites (MOR) of conventional and bulk fill after additional polishing. The specimens were prepared from Filtek Bulk Fill (FBF), Tetric N-Ceram Bulk Fill (TNCBF), Opus Bulk Fill (OBF), X-tra Fil (XTFL), Filtek Z250 XT (XT), Grandioso (GRA), Tetric N-Ceram (TNC), Vittra APS (VT), according to three additional techniques (n = 10): without finishing and polishing, finishing and polishing with abrasive rubbers (Astropol), finishing and polishing with Astropol plus additional polishing with silicon carbide brush. The SR and CA were measured using a profilometer and adapted goniometer, respectively; 3DM used atomic force microscopy (AFM); the micromorphology and DDCP by scanning electron microscopy (SEM) and the MOR by means of X-ray dispersive energy spectroscopy (EDS).

Interfacial Properties and Bottom/Top Hardness Ratio Produced by Bulk Fill Composites in Dentin Cavities.

The aim of this study was to evaluate the bond strength, bottom/top hardness ratio, marginal adaptation, and interfacial nanoleakage of regular viscosity bulk fill composites (RVBFC) and regular viscosity traditional composites (RVTC). Two RVBFC (Filtek Bulk Fill and Aura Bulk Fill) and two RVTC (Filtek Z250XT and Aura) were assessed. Forty conical cavities (4.

Effect of additional polishing methods on the physical surface properties of different nanocomposites: SEM and AFM study.

This evaluated the arrangement of filler particles in depth of nanocomposites, and surface roughness, wettability, microtopography, and micromorphology following additional polishing step. Forty samples of each composite tested [Filtek Z350XT (FZ), IPS Empress Direct (IP)] were fabricated and finished/polished/additionally polished using one of the following methods (n = 10/group): no finishing/polishing (NFP), Sof-Lex Pop-On + no additional polishing (SP), Sof-Lex Pop-On + Astropol rubber polisher (SP+A), and Sof-Lex Pop-On + felt disc with polishing paste (SP+FP). Surface roughness (Ra) and contact angles were measured using a profilometer and goniometer, respectively.

Efficacy of ibuprofen and codeine + paracetamol to reduce immediate bleaching sensitivity caused by in-office tooth bleaching: A randomized, controlled, double-blind clinical trial.

Purpose: To evaluate (1) the efficacy of Ibuprofen and codeine + paracetamol to control immediate bleaching sensitivity caused by in-office tooth bleaching performed with 35% hydrogen peroxide, and (2) tooth shade change caused by 35% hydrogen peroxide.

Methods: In this randomized, controlled and double blind clinical trial, 60 volunteers were divided into three treatment groups: 400 mg placebo (PL)(n=20), 400 mg ibuprofen (IB)(n=20), or 30 mg codeine + 500 mg paracetamol (CP)(n=20). The volunteers were submitted to two bleaching sessions with 35% hydrogen peroxide in 2 applications of 20 minutes each.

In-office tooth bleaching with 38% hydrogen peroxide promotes moderate/severe pulp inflammation and production of ll-1β, TNF-β, GPX, FGF-2 and osteocalcin in rats.

Objectives: To study the intensity of inflammatory infiltrate and production of interleukin-1β (ll-1β), tumor necrosis factor-β (TNF-β), fibroblast growth factor-2 (FGF-2), glutathione peroxidase (GPX), and osteocalcin in response to in-office tooth bleaching in rats.

Material And Methods: Twenty male Wistar rats were randomized into four groups (n=5) according to the received treatment (tooth bleaching or no treatment - control) and the period of euthanasia after treatment (24 h or 10 days). We performed tooth bleaching using a 38% hydrogen peroxide gel on maxillary and mandibular incisors.

Physical-Mechanical Properties and Micromorphology of Calcium Cements Exposed to Polyacrylic and Phosphoric Acids.

Objective: To evaluate if physical and mechanical properties of self-curing calcium hydroxide cements were affected by contact with polyacrylic and phosphoric acids.

Materials And Methods: Resin-containing (Life (LF)) and resin-free (Hydro C (HyC)) materials were subjected to polyacrylic acid conditioning and rinsing (POL); phosphoric acid conditioning and rinsing (PHO); rinsing only; and no treatment ( = 10). Water sorption/solubility, release of hydroxyl ions (pH), roughness (Ra), and impact resistance were evaluated.

Low-level laser therapy (780 nm) combined with collagen sponge scaffold promotes repair of rat cranial critical-size defects and increases TGF-β, FGF-2, OPG/RANK and osteocalcin expression.

The aim of this study was to evaluate the effect of collagen sponge scaffold (CSS) implantation associated with low-level laser therapy (LLLT) on repairing bone defects. A single 5-mm cranial defect was surgically created in forty Wistar rats, which then received one of the following four interventions (n = 10 per group): no treatment (G0); bone defect implanted with collagen sponge scaffold (CSS) alone (G1); defect treated with low-level laser therapy (LLLT) (wavelength 780 nm; total energy density 120 J/cm ; power 50 mW) alone (G2); and CSS associated with LLLT treatment (G3). After surgery, animals in each group were euthanized at 21 days and 30 days (n = 5 per euthanasia time group).

Effect of Instrument Lubricants on the Surface Degree of Conversion and Crosslinking Density of Nanocomposites.

Purpose: The surface degree of conversion and crosslink density of composites should not be affected by the use of instrument lubricants in order to provide long-lasting tooth restorations. This study aimed to analyze the effect of instrument lubricants on the degree of conversion and crosslink density of nanocomposites.

Materials And Methods: Samples (N = 10) were fabricated according to the composites (Filtek Z350 XT, 3M ESPE, St.

Marginal and internal analysis of preheated dental fissure-sealing materials using optical coherence tomography.

Objectives: This study aimed to evaluate the influence of pre-photoactivation temperature on the marginal and internal integrity (occurrence of voids) of fissure-sealing materials on occlusal fissures using optical coherence tomography (OCT).

Methods: Occlusal fissures of 40 human third molars were sealed using a resin-based fissure sealant (Fluroshield) and a flowable composite (Permaflo) photoactivated at 68 °C (preheated) or at room temperature (25 °C) (n=10). After sealing, the teeth were subjected to thermocycling (500 cycles, 5-55 °C) and 14 days of pH cycling (demineralisation for 6 hours/day and remineralisation for 18 hours/day).

Impact of toothbrushing with a dentifrice containing calcium peroxide on enamel color and roughness.

This in vitro study sought to evaluate both the bleaching potential and changes to average surface roughness (Ra) of enamel after brushing with a dentifrice. Fifty-four enamel specimens (4 x 4 x 2 mm) were divided into 3 groups (n = 18) and treated with 1 of 3 dentifrices: 1 with calcium peroxide, and 2 without. The samples were submitted to 20,000 brushing cycles.