Publications by authors named "Bong Ju Moon"

Objective: We aimed to investigate the incidence of delayed-onset neurological deficits (DONDs), DOND-related reoperation rates following adult spinal deformity (ASD) surgery, and efficacy of transverse process hooks (TPHs) at the uppermost instrumented vertebra (UIV) compared to pedicle screws (PSs).

Methods: We included 90 consecutive patients who underwent instrumented fusion from the sacrum to the distal thoracic spine for ASD, with a minimum follow-up of 24 months. Clinical and radiological outcomes were compared between 33 patients in the TPH group and 57 patients in the PS group, using the Scoliosis Research Society-22 Outcomes questionnaire (SRS-22), Medical Outcomes Study Questionnaire Short-Form 36 (SF-36), and various spinal sagittal parameters.

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Objective: Spinal stenosis is a prevalent condition; however, the optimal surgical treatment for central lumbar stenosis remains controversial. This study compared the clinical outcomes and radiological parameters of 3 surgical.

Methods: unilateral laminectomy bilateral decompression with unilateral biportal endoscopy (ULBD-UBE), conventional subtotal laminectomy (STL), and minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF).

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The bioactive glass-ceramic spacer (BGS)-7, a biosynthetic intervertebral fusion material introduced in 2014, has not been the subject of comparative clinical studies on anterior cervical discectomy and fusion (ACDF) surgery. This study, for the first time, aims to compare the radiological and clinical outcomes of the renewed BGS-7, released in 2019, with those of an allograft spacer. The comparison includes a finite element analysis of the biomechanical properties of each implant, adding a novel dimension to the research.

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Spinal cord meningiomas are typically benign, rare tumors that pose clinical challenges owing to their location and potential for spinal cord compression. This study aimed to assess the radiological features of spinal cord meningiomas and the key factors associated with their recurrence. We conducted a retrospective, single-institution study on 67 patients with pathologically confirmed spinal cord meningiomas who were surgically treated between January 2016 and December 2023.

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Article Synopsis
  • Vertebral arterial injury (VAI) can be a serious complication after C1-C2 posterior screw fixation, as observed in a case of a 34-year-old woman with quadriplegia who suffered bilateral VAI caused by her surgical screws.
  • Postoperative imaging revealed that the screws had violated the vertebral arteries but did not result in any neurological deterioration or infarction.
  • The case highlights the importance of careful screw placement to prevent VAI during surgery, as well as the potential for variations in blood circulation to impact patient outcomes.
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  • The study analyzed the effectiveness of anabolic agents versus bisphosphonates in preventing new osteoporotic vertebral fractures (OVF) and aiding in fracture healing among patients with existing OVF, using meta-analysis of randomized controlled trials (RCTs).
  • After screening 518 studies, only 6 RCTs met the criteria, revealing that anabolic agents like teriparatide and romosozumab significantly reduced the risk of new OVF compared to bisphosphonates, with high-certainty evidence for this finding.
  • While anabolic agents were effective in preventing new fractures, there was no significant difference in the healing of existing fractures when comparing teriparatide with alendronate
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Objective: Spinal intramedullary hemangioblastoma is a rare and highly vascularized benign tumor. The characteristics of the tumor, its corresponding location, and surgical outcomes remain unknown. The purpose of this study was to identify risk factors and strategies for neurologic deterioration following hemangioblastoma surgery.

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Study Design: Single-center retrospective study.

Objective: The objective of this study is to identify the factors leading to repeat surgery in patients with cervical ossification of the longitudinal ligament (OPLL) during a minimal 8-year follow-up after the initial surgery.

Summary Of Background Data: The long-term effects of cervical OPLL are well known, but it's not always clear how many patients need to have surgery again because their neurological symptoms get worse.

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Objective: Although adult spinal deformity (ASD) surgery aims to restore and maintain alignment, proximal junctional kyphosis (PJK) may occur. While existing scoring systems predict PJK, they predominantly offer a generalized 3-tier risk classification, limiting their utility for nuanced treatment decisions. This study seeks to establish a personalized risk calculator for PJK, aiming to enhance treatment planning precision.

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Rationale: Neurenteric cysts are rare benign lesions that are usually located in the lower cervical and upper thoracic spine and extremely rare in the craniovertebral junction. It is generally challenging to completely remove the neurenteric cysts of the craniovertebral junction. We report the cases of 2 patients with neurenteric cyst in the ventral craniovertebral junction managed using different treatment strategies.

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Objective: The objective of this study is to evaluate the subsidence performance of a bioactive glass-ceramic (CaO-SiO-PO-BO) spacer in terms of its modulus of elasticity and contact area using mechanical tests and finite element analysis.

Methods: Three spacer three-dimensional models (Polyether ether ketone [PEEK]-C: PEEK spacer with a small contact area; PEEK-NF: PEEK spacer with a large contact area; and Bioactive glass [BGS]-NF: bioactive glass-ceramic spacer with a large contact area) are constructed and placed between bone blocks for compression analysis. The stress distribution, peak von Mises stress, and reaction force generated in the bone block are predicted by applying a compressive load.

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Article Synopsis
  • * Results showed that subsidence occurred in 45.2% of patients and 48.1% of segments, yet both groups (subsidence and non-subsidence) experienced improved pain and disability scores.
  • * Although subsidence increased segmental angle (SA) and cervical sagittal alignment (CSA) over time, the differences in these measurements and fusion rates between the groups were not statistically significant, suggesting subsidence does not majorly impact long-term outcomes if foramen decompression
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This study aimed to investigate whether changes in the bone turnover markers (BTMs) during teriparatide therapy for osteoporotic vertebral compression fractures could reflect therapeutic effects by analyzing the relationship between clinical and radiological features and BTMs. A total of 33 patients with 51 osteoporotic vertebral compression fracture segments were included. Plain radiographs and BTM levels were evaluated at the pretreatment and at 3 months after teriparatide treatment.

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Rationale: Oblique lumbar interbody fusion (OLIF) is an effective and safe surgical technique widely used for treating spondylolisthesis; however, its use is controversial because of several associated complications, including endplate injury. We report a rare vertebral body fracture following OLIF in a patient with poor bone quality.

Patient Concerns: A 72-year-old male patient visited our clinic for 2 years with lower back pain, leg radiating pain, and intermittent neurogenic claudication.

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Article Synopsis
  • The study investigates the occurrence of motor weakness in patients after undergoing oblique lumbar interbody fusion (OLIF), a minimally invasive spinal surgery.
  • Out of 36 patients, only 8% experienced neurological deficits, but they had longer vertebral osteophytes compared to those without deficits.
  • The findings suggest that longer osteophyte length may be a risk factor for post-surgery motor weakness, indicating that additional surgical decompression might be necessary for these patients.
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Rationale: In recent years, oblique lumbar interbody fusion (OLIF), which uses a window between the peritoneum and the iliopsoas muscle to split the muscle to access the lumbar spine, is known as an effective and safe treatment for spinal diseases, such as degenerative disc disease, spondylolisthesis, recurrent disc herniation, and spinal deformity. Despite this fast and useful surgical method, there were often cases of new neurological symptoms or worsening of symptoms after surgery. We analyzed the preoperative risk factors in a patient with neurologic symptoms, such as motor weakness and exacerbation of radiating pain, after OLIF.

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Article Synopsis
  • The study aimed to explore how spinal alignment and genetic factors impact health-related quality of life in older adults with spinal deformities.
  • Researchers assessed sagittal parameters and muscle quality in 120 participants while using various functional scales to gauge disability and pain.
  • They found that specific misalignments in spinal curvature negatively affected quality of life, and identified a significant genetic variant linked to severe cases of adult spinal deformity, providing insights into its underlying causes.
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Objective: The purpose of the present study was to evaluate the natural course of primary degenerative sagittal imbalance (PDSI), its aggravating factors, and health-related quality of life (HRQoL) associated with various spinal alignment parameters (SAPs) in patients with PDSI who have not undergone surgery.

Methods: One hundred three participants volunteered to participate. The SAPs, including T1 pelvic angle (T1PA), thoracolumbar tilt, and thoracolumbar slope (TLS), were measured on whole-spine standing radiographs.

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Background: Percutaneous-short segment screw fixation (SSSF) without bone fusion has proven to be a safe and effective modality for thoracolumbar spine fractures (TLSFs). When fracture consolidation is confirmed, pedicle screws are no longer essential, but clear indications for screw removal following fracture consolidation have not been established.

Methods: In total, we enrolled 31 patients with TLSFs who underwent screw removal following treatment using percutaneous-SSSF without fusion.

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Objective: Anterior odontoid screw fixation (AOSF) is a safe and effective treatment for type II and rostral type III odontoid fracture. This study aimed to report the outcomes of the AOSF surgery and evaluate the potential risk factors of surgical failure.

Methods: We enrolled 63 patients who underwent AOSF.

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Objective: Controversy remains regarding the optimal methods for resection of the vertebral body, reconstruction of the anterior column, and decompression of the spinal cord in patients who have severe vertebral body destruction of the thoracic or lumbar spine with associated neurologic impairment. We report an alternative technique for primary treatment and salvage involving single-stage corpectomy followed by reconstruction of the anterior column using double small mesh cages via the posterior-only approach.

Methods: Plain radiographs and computed tomography scans, taken at different intervals, were used to measure local kyphosis, segmental height, and fusion grade.

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Article Synopsis
  • - The study investigates spinal sagittal imbalance in older Korean adults, particularly focusing on how farming-related activities and prolonged crouched postures contribute to this condition, which has been noted primarily in agricultural regions of Korea and Japan.
  • - Researchers analyzed data from 103 participants, comparing radiological parameters, MRI results, fractures, and muscle changes, while also looking at the impact of annual working hours in farming on spinal health.
  • - Findings revealed that farmers had significant differences in spinal alignment measurements and experienced more severe back pain and disability compared to non-farmers, indicating a link between occupational activities and spinal health issues.
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Background: Adult-onset Langerhans cell histiocytosis (LCH) with simultaneous involvement of the high cervical spine and the hypothalamus is rare.

Case Description: We have reported a case of adult-onset LCH in the second cervical vertebra with bony destruction and subsequent diabetes insipidus due to simultaneous involvement of the hypothalamus and pituitary stalk. Magnetic resonance imaging of the hypothalamus and pituitary lesion and immunohistochemistry of the cervical lesion revealed LCH.

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  • Extraosseous Ewing sarcoma (EES) is a spinal tumor often mistaken for others due to its MRI characteristics, making accurate diagnosis challenging before treatment.
  • A 54-year-old woman presented with upper back pain and was initially diagnosed with spinal schwannoma, but surgical resection revealed it was actually EES, confirmed by histopathology and immunohistochemistry.
  • Following surgery, the patient underwent radiation therapy without chemotherapy, and five years later, there were no signs of tumor recurrence or new lesions.
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Background: Thoracolumbar burst fractures (TLBFs) are the most common spinal trauma; however, their appropriate management has not yet been determined. In this study, we aimed to compare the clinical and radiological results of percutaneous pedicle screw fixation (PPSF) following posterior decompression technique versus anterior corpectomy and fusion technique for the treatment of TLBFs.

Methods: A total of 46 patients (2002-2015) with TLBFs were included in this study.

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