Vertical Jump Height Estimation Using Low-Sampling IMU in Countermovement Jumps: A Feasible Alternative to Motion Capture and Force Platforms.

Vertical jump height from a countermovement jump is a widespread metric to assess the lower limb functionality. Motion capture systems and force platforms are considered gold standards to estimate vertical jump height; however, their use in ecological settings is limited. This study aimed to evaluate the feasibility of low-sampling-rate inertial measurement units as an alternative to the gold standard systems.

Effects of Different Inertial Measurement Unit Sensor-to-Segment Calibrations on Clinical 3-Dimensional Humerothoracic Joint Angles Estimation.

Calibrating inertial measurement units (IMUs) involves converting orientation data from a local reference frame into a clinically meaningful reference system. Several solutions exist but little work has been done to compare different calibration methods with each other and an optical motion capture system. Thirteen healthy subjects with no signs of upper limb injury were recruited for this study and instrumented with IMU sensors and optical markers.

Effects of IMU sensor-to-segment calibration on clinical 3D elbow joint angles estimation.

Inertial Measurement Units (IMU) require a sensor-to-segment calibration procedure in order to compute anatomically accurate joint angles and, thereby, be employed in healthcare and rehabilitation. Research literature proposes several algorithms to address this issue. However, determining an optimal calibration procedure is challenging due to the large number of variables that affect elbow joint angle accuracy, including 3D joint axis, movement performed, complex anatomy, and notable skin artefacts.

Multimodal force and temperature tactile sensor based on a short-channel organic transistor with high sensitivity.

In this manuscript, we report on a novel architecture for the fabrication of highly sensitive multimodal tactile transducers, for the simultaneous detection of temperature and force. Such devices are based on a flexible Organic Charge Modulated Field Effect Transistor (OCMFET) coupled with a pyro/piezoelectric element, namely a commercial film of poly-vinylene difluoride (PVDF). The reduction of the channel length, obtained by employing a low-resolution vertical channel architecture, allowed to maximize the ratio between the sensing area and the transistor's channel area, a technological approach that allows to considerably enhance both temperature and force sensitivity, while at the same time minimize the sensor's dimensions.

Hedonic and eudaimonic well-being for sustainable development in university students: personality traits or acceptance of change?

Introduction: The psychology of sustainability and sustainable development aims to contribute to the establishment of a culture of sustainability regarding the 2030 Agenda and its 17 sustainable development goals.

Methods: In this framework, this study examined the associations between acceptance of change and well-being (hedonic and eudaimonic sides), controlling for the effects of personality traits, in 284 Italian university students.

Results: Acceptance of change explained additional variance over personality traits regarding hedonic and eudaimonic well-being.

Estimating the common agricultural policy milestones and targets by neural networks.

The New Delivery Model, introduced by the 2023-2027 Common Agricultural Policy, shifts the focus of policy programming and design from a compliance-based approach to one based on performance. The objectives indicated in the national strategic plans are monitored through the definition of a set of milestones and targets. This makes it necessary to define realistic and financially consistent target values.

Human capital sustainability leadership: From personality traits to positive relational management.

Introduction: Constructing positive and supportive relationships is fundamental for healthy workers and healthy organizations and to cope with the current challenging work scenario. Organizations need to acknowledge the relevance of the relationships for workers and organizational well-being and adopt managing practices that enhance healthy relationships for sustainability and sustainable development.

Methods: The current research sought to investigate the associations between positive relational management (PRM) and human capital sustainability leadership (HCSL), taking into account personality traits.

An N-heterocyclic carbene iridium(III) complex as a potent anti-cancer stem cell therapeutic.

Cancer stem cells (CSCs) represent a difficult to treat cellular niche within tumours due to their unique characteristics, which give them a high propensity for resistance to classical anti-cancer treatments and the ability to repopulate the tumour mass. An attribute that may be implicated in the high rates of recurrence of certain tumours. However, other characteristics specific to these cells, such as their high dependence on mitochondria, may be exploited for the development of new therapeutic agents that are effective against the niche.

Simultaneous recording of electrical and metabolic activity of cardiac cells using an organic charge modulated field effect transistor array.

electrogenic cells monitoring is an important objective in several scientific and technological fields, such as electrophysiology, pharmacology and brain machine interfaces, and can represent an interesting opportunity in other translational medicine applications. One of the key aspects of cellular cultures is the complexity of their behavior, due to the different kinds of bio-related signals, both chemical and electrical, that characterize these systems. In order to fully understand and exploit this extraordinary complexity, specific devices and tools are needed.

Epidermal Electrodes with Ferrimagnetic/Conductive Properties for Biopotential Recordings.

Interfacing ultrathin functional films for epidermal applications with external recording instruments or readout electronics still represents one of the biggest challenges in the field of tattoo electronics. With the aim of providing a convenient solution to this ever-present limitation, in this work we propose an innovative free-standing electrode made of a composite thin film based on the combination of the conductive polymer PEDOT:PSS and ferrimagnetic powder. The proposed epidermal electrode can be directly transferred onto the skin and is structured in two parts, namely a conformal conductive part with a thickness of 3 μm and a ferrimagnetic-conductive part that can be conveniently connected using magnetic connections.

Parylene C-Based, Breathable Tattoo Electrodes for High-Quality Bio-Potential Measurements.

A breathable tattoo electrode for bio-potential recording based on a Parylene C nanofilm is presented in this study. The proposed approach allows for the fabrication of micro-perforated epidermal submicrometer-thick electrodes that conjugate the unobtrusiveness of Parylene C nanofilms and the very important feature of breathability. The electrodes were fully validated for electrocardiography (ECG) measurements showing performance comparable to that of conventional disposable gelled Ag/AgCl electrodes, with no visible negative effect on the skin even many hours after their application.

Policy responses to COVID-19 pandemic waves: Cross-region and cross-sector economic impact.

This paper proposes a modelling approach to assess the cross-region and cross-sector economic impacts of the restrictions imposed by governments to contain the COVID-19 pandemic. The nationwide lockdown imposed in Italy during the first wave of the pandemic is used as a benchmark. However, the adopted approach allows an ex-ante assessment of alternative policy responses, in the event of successive pandemic waves, in order to rationalise the policy intervention and reach the best possible compromise between containing the risk of contagion and reducing economic losses.

Comparing optical and electromagnetic tracking systems to facilitate compatibility in sports kinematics data.

Electromagnetic (EM) tracking has been used to quantify biomechanical parameters of the lower limb and lumbar spine during ergometer rowing to improve performance and reduce injury. Optical motion capture (OMC) is potentially better suited to measure comprehensive whole-body dynamics in rowing. This study compared accuracy and precision of EM and OMC displacements by simultaneously recording kinematics during rowing trials at low, middle, and high rates on an instrumented ergometer (n=12).

In Vitro Multiparametric Cellular Analysis by Micro Organic Charge-modulated Field-effect Transistor Arrays.

Modern electrophysiology has been constantly fueled by the parallel development of increasingly sophisticated tools and materials. In turn, discoveries in this field have driven technological progress in a back-and-forth process that ultimately determined the impressive achievements of the past 50 years. However, the most employed devices used for cellular interfacing (namely, the microelectrode arrays and microelectronic devices based on transistors) still present several limitations such as high cost, the rigidity of the materials, and the presence of an external reference electrode.

Dynamic Surface Electromyography Using Stretchable Screen-Printed Textile Electrodes.

Objective: Wearable devices have created new opportunities in healthcare and sport sciences by unobtrusively monitoring physiological signals. Textile polymer-based electrodes proved to be effective in detecting electrophysiological potentials but suffer mechanical fragility and low stretch resistance. The goal of this research is to develop and validate in dynamic conditions cost-effective and easily manufacturable electrodes characterized by adequate robustness and signal quality.

Interfacing cells with organic transistors: a review of in vitro and in vivo applications.

Recently, organic bioelectronics has attracted considerable interest in the scientific community. The impressive growth that it has undergone in the last 10 years has allowed the rise of the completely new field of cellular organic bioelectronics, which has now the chance to compete with consolidated approaches based on devices such as micro-electrode arrays and ISFET-based transducers both in in vitro and in vivo experimental practice. This review focuses on cellular interfaces based on organic active devices and has the intent of highlighting the recent advances and the most innovative approaches to the ongoing and everlasting challenge of interfacing living matter to the "external world" in order to unveil the hidden mechanisms governing its behavior.

Electrolyte-gated transistors for enhanced performance bioelectronics.

Electrolyte-gated transistors (EGTs), capable of transducing biological and biochemical inputs into amplified electronic signals and stably operating in aqueous environments, have emerged as fundamental building blocks in bioelectronics. In this Primer, the different EGT architectures are described with the fundamental mechanisms underpinning their functional operation, providing insight into key experiments including necessary data analysis and validation. Several organic and inorganic materials used in the EGT structures and the different fabrication approaches for an optimal experimental design are presented and compared.

Stretchable screen-printed PEDOT:PSS electrodes for upper-arm surface electromyography.

In the past ten years, wearable electronics underwent tremendous growth. Undoubtedly, one of the fields that led this trend is represented by biomedical applications. In this field, wearable technologies can provide unique features such as the unobtrusive monitoring of biopotentials.

Electrophysiological Responses from the Human Tongue to the Six Taste Qualities and Their Relationships with PROP Taster Status.

Taste buds containing receptor cells that primarily detect one taste quality provide the basis for discrimination across taste qualities. The molecular receptor multiplicity and the interactions occurring between bud cells encode information about the chemical identity, nutritional value, and potential toxicity of stimuli before transmitting signals to the hindbrain. PROP (6--propylthiouracil) tasting is widely considered a marker for individual variations of taste perception, dietary preferences, and health.

Phosphorescent Cationic Heterodinuclear Ir /M Complexes (M=Cu , Au ) with a Hybrid Janus-Type N-Heterocyclic Carbene Bridge.

A novel class of phosphorescent cationic heterobimetallic Ir /M complexes, where M =Cu (4) and Au (5), is reported. The two metal centers are connected by the hybrid bridging 1,3-dimesityl-5-acetylimidazol-2-ylidene-4-olate (IMesAcac) ligand that combines both a chelating acetylacetonato-like and a monodentate N-heterocyclic carbene site coordinated onto an Ir and a M center, respectively. Complexes 4 and 5 have been prepared straightforwardly by a stepwise site-selective metalation with the zwitterionic [(IPr)M (IMesAcac)] metalloproligand (IPr=1,3-(2,6-diisopropylphenyl)-2H-imidazol-2-ylidene) and they have been fully characterized by spectroscopic, electrochemical, and computational investigation.

A three-dimensional micro-electrode array for in-vitro neuronal interfacing.

Objective: In this paper, we report on the development of an easy-to-fabricate three-dimensional Micro-Electrode Array (3D-MEA) specifically designed for brain-on-a-dish applications.

Approach: The proposed device consists of pillar-shaped gold microelectrodes realized by electroplating directly on top of a standard MEA, making this approach highly versatile and convenient for batch fabrication. Moreover, with this simple technique, it is possible to obtain electrodes with a height of more than 100 µm onto different kind of substrates, ranging from glass to flexible plastic ones.

Red-emitting neutral rhenium(i) complexes bearing a pyridyl pyridoannelated N-heterocyclic carbene.

Two novel rhenium(i) tricarbonyl complexes of general formula fac-[Re(N^C:)(CO)X] are herein presented, where N^C: is the pyridoannelated N-heterocyclic carbene (NHC) arising from 2-(2-pyridinyl)imidazo[1,5-a]pyridinium hexafluorophosphate proligand, namely [pyipy]PF, and X being Cl and Br. The synthetic pathway is a one-pot reaction that starts from the azolium salt as the NHC source and [Re(CO)X] to yield the desired charge-neutral fac-[Re(pyipy)(CO)X] complexes (1-2). Both complexes were thoroughly characterized by spectroscopic, electrochemical, theoretical investigation as well as X-ray diffraction analysis.

Validation of Polymer-Based Screen-Printed Textile Electrodes for Surface EMG Detection.

In recent years, the variety of textile electrodes developed for electrophysiological signal detection has increased rapidly. Among the applications that could benefit from this advancement, those based on surface electromyography (sEMG) are particularly relevant in rehabilitation, training, and muscle function assessment. In this work, we validate the performance of polymer-based screen-printed textile electrodes for sEMG signal detection.

From MEAs to MOAs: The Next Generation of Bioelectronic Interfaces for Neuronal Cultures.

Since their introduction in the early 1970s, microelectrode arrays (MEAs) have been dominating the electrophysiology market thanks to their reliability, extreme robustness, and usability. Over the past 40 years, silicon technology has also played a role in the advancement of the field, and CMOS-based in vitro and in vivo systems are now able to achieve unprecedented spatial resolutions, giving the possibility to unveil hidden behavior of cellular aggregates down to the subcellular level. However, both the MEAs and silicon-based electronic devices present unavoidable problems such as their expensiveness, the usual rigidity of the employed materials, and the need of an (usually bulky) external reference electrode.

An organic neurophysiological tool for neuronal metabolic activity monitoring.

Monitoring cell metabolism is considered a relevant methodology in several scientific fields ranging from fundamental biology research to neuro-toxicology. In the last 20 years, several neuro-pharmacological and neuro-toxicological approaches have been developed, with the intent of addressing the increasing demand for real-time, non-invasive systems capable of continuously and reliably monitoring cellular activity. In this paper, an Organic Charge Modulated Field Effect Transistor-based device is proposed as a promising tool for neuro-pharmacological applications, thanks to its ultra-high pH sensitivity and a simple fabrication technology.