Publications by authors named "Bonfadini Silvia"

Article Synopsis
  • A study evaluated the long-term effectiveness of the MiniMed™ 780G advanced hybrid closed-loop (AHCL) system in 296 adults with type 1 diabetes over a period of up to 2 years.
  • Results showed significant improvements in continuous glucose monitoring metrics, with time in range increasing notably from 58.1% to 70.3% during the first quarter and maintaining this trend for the entire study.
  • Lower baseline glycated hemoglobin (HbA) levels were a key predictor of better glycemic control, although participants with higher baseline HbA experienced the most significant improvements.
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Article Synopsis
  • The study examines the impact of glycemic control on COVID-19 outcomes in diabetic patients, focusing on factors like hyperglycemia, inflammation, and clinical history.
  • It involved a retrospective analysis of 291 diabetic patients, finding that high blood glucose levels at admission and poor kidney function significantly increased the risk of mortality and longer hospital stays.
  • Interestingly, while hyperglycemia directly correlated with higher mortality, certain inflammatory markers showed indirect effects, and a higher basophil count appeared to be protective against mortality.
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Aim: To re-evaluate the diagnostic criteria of insulin resistance hepatic iron overload based on clinical, biochemical and histopathological findings.

Methods: We studied 81 patients with hepatic iron overload not explained by known genetic and acquired causes. The metabolic syndrome (MS) was defined according to ATPIII criteria.

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