[Disturbanes in electrostatic balance of erythrocyte membranes in experimental D-hypovitaminosis].

Violation of electrostatic balance in the erythrocyte membranes with experimental D-hypovitaminosis is determined by the method of potentiometric titration. It is pronounced in modification of quantity and pK of accessible polar groups and in a decrease in total membrane electronegative charge. This violation is supposed to be provoked by a considerable increase in cholesterol content in the membranes and to reflect a modification in the character and bond strength of protein lipid complexes caused by interaction of cholesterol with membrane components.