MULTIFACTORIAL REGRESSION MODEL FOR PREDICTING THE LEVEL OF HEAT SENSITIVITY IN HEALTHY YOUNG PEOPLE IN THE CONTEXT OF GLOBAL WARMING.

Objective: The aim: To create a mathematical model for predicting the level of heat sensitivity in healthy young people based on multivariate regression analysis.

Patients And Methods: Materials and methods: 150 healthy young people aged 17-20 years answered the questionnaire "Levels of heat sensitivity", underwent a heat test and mathematical analysis of the heart rate, after which the results were used to build a regression model of heat sensitivity.

Results: Results: The model of mathematical prediction of heat sensitivity (CHSL1/CHSL2), which we proposed for the first time, takes into account the most significant factors that influence the determination of higher and lower sensitivity to heat (Q1-Q6, %LF2, %HF1, %HF2, HR1, HR2), so its use will allow timely identi¬fication of individuals who are particularly susceptible to the effects of elevated ambient temperature and prevent the development of potential negative consequences of this exposure.

Mechanical Behavior of Titanium Based Metal Matrix Composites Reinforced with TiC or TiB Particles under Quasi-Static and High Strain-Rate Compression.

The mechanical behavior of titanium alloys has been mostly studied in quasi-static conditions when the strain rate does not exceed 10 s, while the studies performed in dynamic settings specifically for Ti-based composites are limited. Such data are critical to prevent the "strength margin" approach, which is used to assure the part performance under dynamic conditions in the absence of relevant data. The purpose of this study was to obtain data on the mechanical behavior of Ti-based composites under dynamic condition.

[Methods of the treatment of patients with intraarticular fractures of the tibia proximal end].

Literature review presents surgical methods of the treatment of patients with intraarticular fractures of proximal end of tibia, classification of fractures, peculiarities of the diagnostics, methods of bone fragment osteosynthesis, defectplasty of spongy bone tissue.

[Reabilitation patients with intraarticular fractures of the tibial proximal end].

The works is devoted to guestions of optimization results of surgical treatment of patients with intraarticular fractures of the tibial proximal end. Active and passive mobilization of knee joint was carried out from the first days after operation. As of the result use of improved and developt systems for diagnosis and surgical treatment of 136 patients with intra-articulare fractures of the proximal tibia end the specific weight positive immediate results has come up to 93%, that of long-term results--to 89%.

[Surgical treatment for compression fractures of the tibia condyles].

Results are submitted of surgical treatment of 69 patients presenting with compression fracture of condyles of the tibia. The elaborated management scheme of the above kind of fractures was found to have ensured a positive result in 84 percent of cases.

[Replacement of bone defects with a polyurethane composition with hydroxyapatite high-filling ].

There have been obtained high-filling polyurethane compositions with hydroxyapatite. Compositions with hydroxyapatite and immunomodulator in the polyurethane base acquire better adhesiveness and improved strength characteristics as evidenced by physical-and-clinical studies made. Modal operations are developed in test animals on bone defects replacing that carry a high mechanical load.

[Preparation and selection of monoclonal antibodies for detecting hepatitis B surface antigen in blood sera].

HV monoclonal antibodies (MAb) were produced in order to improve the quality of HBsAg detection and their specific characteristics were compared with those of other MAbs. MAbs were characterized by asymmetric interactions with the antigen when used as first or second antibodies. The reactivity of a panel of HV and X MAb to ad and ay subtypes was studied by enzyme immunoassay.

[Expression of hepatitis A virus recombinant proteins in Escherichia coli].

On the basis of coding regions on the fragments of genes P1 and P2 of hepatitis A virus (HAV) recombinant proteins of this virus have been synthesized in the prokaryotic expressing system of E. coli, isolated and studied with the use of sera obtained from hepatitis A patients. The capacity of HAV recombinant proteins for binding with the sera of patients with hepatitis A in the acute stage has been shown with the use of immunoblotting and the indirect solid-phase enzyme immunoassay.

[Optimization of preparation conditions of an inactivated hepatitis A vaccine and its characteristics].

Modernization of the protocol and optimization of the technology of preparation of inactivated hepatitis A vaccine helped prepare the experimental lots of inactivated vaccine meeting all the requirements to such preparations and the WHO recommendations.

[Surgical tactics in acute gastrointestinal hemorrhage].

The results of treatment of 595 patients with acute gastro-intestinal bleeding are presented. Ulcer disease is the most frequent cause of bleeding. In its diagnosis, the use of gastroduodeno-fibroscopy is effective.

[Genesis of biorhythms of the cardiointervalogram in its evolutionary aspect].

Statistical characteristics and latent biorhythms of the frog, rabbit and human cardiointervalograms were studied in the volutionary aspect with the aid of ACBT-M 6000 computer. Some mechanisms of temporary organization of the heart rhythm were revealed with regard to the level of organization of biological objects. Evolutionary aspects of analysis of the heart biorhythms provide an approach to their genesis.