Comparison of efficacy and safety of two fixed-dose combination regimens for tuberculosis in the Chinese population.

To date, there have been few studies on the dosage of fixed-dose combination (FDC) for the treatment of tuberculosis (TB) in the Chinese population. The aim of this study was to evaluate the efficacy and safety of two FDC regimens in two provinces with a high tuberculosis burden. A total of 2,353 newly diagnosed active pulmonary TB patients were recruited from Shandong Province (n=1,223) and Jilin Province (n=1,130).