Publications by authors named "Bona Liu"
Article Synopsis
- The study analyzes trends in RNA methylation research in cancer over the last decade, utilizing bibliometric tools to gather data from significant research databases.
- China leads in publication numbers and citations, with specific recognition of Sun Yat Sen University and author Zhang, Wei, while key journals include Frontiers in Oncology and Molecular Cancer.
- Research topics are categorized into five main clusters, highlighting RNA methylation's role in cancer prognosis, therapeutic targets, and mechanisms of tumor development.
Article Synopsis
- Scientists created a special computer program, called a nomogram, to help predict if patients with a type of lung cancer have a specific gene change called EGFR mutation.
- They studied 438 patients who had surgery and checked their gene tests to find patterns in CT images of their tumors.
- The nomogram turned out to be really good at predicting the gene status and was more helpful than other methods, which can aid doctors in deciding the best treatment for patients.
Objective: Immune checkpoint inhibitors (ICIs), specifically targeting the programmed cell death protein-1 or its ligand (PD-1/PD-L1), have been extensively used in the treatment of a spectrum of malignancies, although the predictive biomarkers remain to be elucidated. This study aims to investigate the association between baseline circulating levels of cytokines and the creatinine/cystatin C ratio (CCR) with the treatment outcomes of ICIs in patients with advanced cancer.
Methods: The pre-treatment circulating levels of 10 cytokines (PD-L1, CTLA4, CXCL10, LAG3, HGF, CCL2, MIG, GRANB, IL-18, and IL-6) were measured via automated capillary-based immunoassay platform in the serum of 65 advanced cancer patients treated with anti-PD-1/PD-L1-based systemic therapy and 10 healthy volunteers.
Background: Recent reviews have outlined the main nanomaterials used in relation to gastrointestinal tumors and described the basic properties of these materials. However, the research hotspots and trends in the application of nanomaterials in gastric cancer (GC) remain obscure.
Aim: To demonstrate the knowledge structure and evolutionary trends of research into the application of nanomaterials in GC.
Article Synopsis
- This study investigates the role of the creatinine-to-cystatin C ratio (CCR) and body composition parameters in predicting outcomes for gastric cancer patients receiving PD-1 inhibitors, focusing on their prognostic value in the context of metastatic cancer treatment.
- A total of 113 patients were analyzed using advanced imaging techniques to measure skeletal muscle and fat indices, and statistical methods were applied to assess the relationship between these metrics and patient survival rates.
- Findings revealed that low CCR and low subcutaneous adipose tissue index (SATI) are linked to poorer treatment responses and significantly decreased progression-free and overall survival rates, highlighting their importance as prognostic markers in metastatic gastric cancer.
Background: To examine the trends in morbidity and mortality among ovarian cancer patients with liver metastases, and investigate the impact of different treatments on both overall survival (OS) and cancer-specific survival (CSS).
Methods: 2,925 ovarian cancer patients with liver metastases from Surveillance, Epidemiology, and End Results 2010-2019 were included. The primary endpoint was considered as OS and CSS.
To highlight the knowledge structure and evolutionary trends in research on autophagy in lung cancer. Research publications on autophagy in lung cancer were retrieved from the Web of Science Core Collection database. VOSviewer and CiteSpace data analysis software were used for the bibliometric and visualization analysis of countries, institutions, authors, journals, and keywords related to this field.
View Article and Find Full Text PDFBackground: Glutathione S-transferases (GSTs) have proved to be involved in the detoxifying several carcinogens and may play an important role in carcinogenesis of cancer. Previous studies on the association between Glutathione S-transferase M1 (GSTM1) polymorphism and gastric cancer (GC) risk reported inconclusive results. To get a precise result, we conducted this present meta-analysis through pooling all eligible studies.
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