A semantic segmentation method to analyze retinal vascular parameters of diabetic nephropathy.

Introduction: By using spectral domain optical coherence tomography (SD-OCT) to measure retinal blood vessels. The correlation between the changes of retinal vascular structure and the degree of diabetic nephropathy is analyzed with a full-pixel Semantic segmentation method.

Methods: A total of 120 patients with diabetic nephropathy who were treated in the nephrology department of Quzhou People's Hospital from March 2023 to March 2024 were selected and divided into three groups according to the urinary albumin creatinine ratio (UACR).

Microinvasive intrascleral double continuous suture repair surgery for cyclodialysis clefts.

Background: The traditional suturing method for cyclodialysis cleft usually requires an incision in the sclera for direct suturing, resulting in greater damage and a high risk of postoperative complications. The purpose of this work is to propose a newly intrascleral double continuous suture repair technique for the treatment of cyclodialysis clefts.

Methods: Seven patients with cyclodialysis cleft underwent microinvasive intrascleral double continuous suture repair surgery to restore the attachment of the detached ciliary body to the sclera without scleral incision.

Analysis of retinal arteriolar and venular parameters in primary open angle glaucoma.

Aim: To measure the retinal vessels of primary open angle glaucoma (POAG) patients on spectral domain optical coherence tomography (SD-OCT) with a full-width at half-maximum (FWHM) algorithm to better explore their structural changes in the pathogenesis of POAG.

Methods: In this retrospective case-control study, the right eyes of 32 patients with POAG and 30 healthy individuals were routinely selected. Images of the supratemporal and infratemporal retinal vessels in the B zones were obtained by SD-OCT, and the edges of the vessels were identified by the FWHM method.

New compounds from the stems of Merr. and their in vitro anti-inflammatory activity.

Three new compounds, 4,5,6,7-tetramethoxy-3-benzoylbenzofuran (), 4-hydroxy-3,5,6-trimethoxydihydrochalcone-2-O-β-D-glucopyranoside () and 2-hydroxy-3,4,5,6-tetramethoxyphenylethyl benzoate () along with five known flavonoids were isolated from the dichloromethane fraction of the stems of Merr.'s ethanol extracts. The compounds were obtained by chromatographic methods and the structure elucidation was completed primarily on the basis of spectroscopic analyses, all of these compounds were isolated from for the first time.

New steroidal glycosides from the rhizomes of Smilax nipponica and their anti-inflammatory activities.

Herein, five new steroidal glycosides (Smilnipponicoside A-E) with five known congeners were isolated from the ethanol extracts of the rhizomes of Smilax nipponica Miq. Their structures were established by 2D NMR spectroscopic techniques (HMBC, HSQC, H,H-COSY and NOESY), together with mass spectrometry, then comparison with the data in literature. The new compounds were subjected to evaluate anti-inflammatory in vitro.

New compounds from the stems of Fissistigma oldhamii var. longistipitatum and their cytotoxic activities.

Two new aporphine alkaloids, (R)-1,2-methylenedioxy-3,9-dimethoxy-11-hydroxy-N- carbamoyl-noraporphine (1) and 3,10,11-trimethoxy-1,2-methylenedioxy-7-oxoaporphine(2), and one new dihydrochalcone, 4',5'-dimethoxy-2'-hydroxy-3',6'-quinodihydrochalcone (3), along with five known alkaloids were isolated from the ethanol extracts of the stems of Fissistigma oldhamii var. longistipitatum. The compounds were obtained by various classical column chromatographic methods, and the structure elucidation was completed primarily on the basis of spectroscopic analysis, such as UV, NMR and HR-ESI-MS.