Publications by authors named "Bolla E"

Article Synopsis
  • * A unique case is presented where a patient with a long history of AS was diagnosed with FMF after experiencing recurrent symptoms; laboratory tests confirmed the condition.
  • * The patient's treatment with colchicine led to significant improvement, emphasizing the importance of recognizing the relationship between AS and FMF in medical practice.
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  • Systemic lupus erythematosus (SLE) significantly increases the risk of cardiovascular disease, prompting a study to evaluate traditional cardiovascular risk factors in SLE patients worldwide between 2015 and 2020.
  • The study included 3,401 SLE patients from 24 countries, predominantly women, revealing high rates of hypertension (35.6%), obesity (23.7%), and hyperlipidaemia (19.8%), with poor control of these risk factors across the board.
  • Notably, patients with antiphospholipid syndrome had higher prevalence of cardiovascular risks but showed better control of blood pressure and lipid levels compared to those without, highlighting international discrepancies in risk factor management.
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  • * There are concerns that COVID-19 vaccines might cause autoimmune diseases in previously healthy people, with a case reported of a patient developing anti-MDA5 positive dermatomyositis after receiving the third vaccine dose.
  • * The patient experienced severe symptoms and required multiple treatments, including corticosteroids and rituximab, highlighting the need for further investigation on the rare autoimmune responses potentially linked to COVID-19 vaccines.
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  • Cariprazine (CAR) is an antipsychotic used to treat schizophrenia and bipolar disorder, acting as a partial agonist on dopamine receptors D2 and D3.
  • This pilot study explored how certain single nucleotide polymorphisms (SNPs) in DRD2 and DRD3 genes affect patient responses to CAR treatment, using the Brief Psychiatric Rating Scale (BPRS).
  • Significant associations were found between specific DRD2 SNPs and treatment response, suggesting a potential method to predict patient outcomes with CAR—an important step toward personalized medicine for these disorders.
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The morphology of juveniles of Mithraculus forceps A. Milne-Edwards, 1875, raised in the laboratory, is described. The larvae were obtained from ovigerous females collected in the wild, maintained in the rearing system for culture of crabs (400 L).

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The complete larval development of Amphithrax hemphilli was described, illustrated, and compared with that of the previously described larvae of the genus Mithrax sensu lato. Specimens of A. hemphilli were sampled from the northeastern Brazilian coast.

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Objectives: We aimed to perform a bibliometric analysis of original research articles on Behçet's syndrome (BS) published over the last 20 years prior to the COVID-19 pandemic, and to systematically describe their characteristics and citation records.

Methods: The PubMed database was searched for any article published on BS between 2000 and 2019. We identified all original research articles and categorised them by country of origin and type of research, i.

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Background: Cardiovascular disease (CVD) is the foremost cause of morbidity and deaths in antiphospholipid syndrome (APS), driven by thrombo-inflammation and atherothrombosis mechanisms. Metabolic syndrome (MetS) is a proinflammatory and prothrombotic state characterized by increased CVD risk. We aimed to evaluate the prevalence of MetS in APS patients compared to rheumatoid arthritis (RA) and diabetes mellitus (DM) and its associations with clinical and laboratory patient characteristics and vascular ultrasound (US) markers of subclinical atherosclerosis.

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Background: Crisis Resolution Home Treatment (CRHT) is an alternative to inpatient treatment for acute psychiatric crises management. However, evidence on CRHT effectiveness is still limited. In the Canton of Ticino (Southern Switzerland), in 2016 the regional public psychiatric hospital replaced one acute ward with a CRHT.

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Introduction: Cariprazine is a third-generation antipsychotic, approved for the treatment of schizophrenia and bipolar disorder and used off-label for schizoaffective disorder and treatment-resistant depression. Cariprazine is a partial agonist at dopamine receptors D2 and D3 and serotonin receptor 5HT1A and an antagonist at serotonin receptors 5HT2B and 5HT2A. It is metabolized by CYP3A4 in desmetyl-cariprazine and didesmethyl-cariprazine, both active metabolites with a half-life of 1-2 days and 2-3 weeks, respectively.

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Objective: Antiphospholipid syndrome (APS) is characterised by increased cardiovascular morbidity and mortality, related to thrombo-inflammatory and atherogenic mechanisms. We examined the achievement of traditional cardiovascular risk factor (CVRF) therapeutic goals in APS versus other high cardiovascular risk disorders such as rheumatoid arthritis (RA) and diabetes mellitus (DM), and trends over time.

Methods: 122 patients with APS (74 primary APS, female 68%, mean age 44.

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Background: Crisis Resolution and Home Treatment (CRHT) teams represent a community-based mental health service offering a valid alternative to hospitalization. CRHT teams have been widely implemented in various mental health systems worldwide, and their goal is to provide care for people with severe acute mental disorders who would be considered for admission to acute psychiatric wards. The evaluation of several home-treatment experiences shows promising results; however, it remains unclear which specific elements and characteristics of CRHT are more effective and acceptable.

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Cannabis use is considered an important risk factor for the development of psychotic illness and is associated with worse outcomes of the disorder. This study aimed to determine through a meta-analytic approach whether patients at the onset of schizophrenia with comorbid cannabis use (SCH CU+) show a different pattern of brain abnormalities as compared to patients with no comorbid cannabis use (SCH CU-). Ten Magnetic Resonance Imaging (MRI) studies were identified as suitable for analysis leading to the inclusion of n= 465 patients with schizophrenia (n= 227 SCH CU+ and n= 238 SCH CU-) and n= 366 healthy controls.

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Aims: Usually, spinal cord injury (SCI) develops into a glial scar containing extracellular matrix molecules including chondroitin sulfate proteoglycans (CSPGs). Chondroitinase ABC (ChABC), from Proteus vulgaris degrading the glycosaminoglycan (GAG) side chains of CSPGs, offers the opportunity to improve the final outcome of SCI. However, ChABC usage is limited by its thermal instability, requiring protein structure modifications, consecutive injections at the lesion site, or implantation of infusion pumps.

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Objective: To describe admissions to an inpatient psychiatric unit in Italy over a two-year period and explore the influence of demographics, clinical variables and organisational and context-related factors on length of stay.

Methods: Data were obtained from clinical records and recorded by a psychiatrist through a proper checklist.

Results: Shorter admissions involved patients with personality disorders and substance use disorders.

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The juvenile development of Callinectes danae was investigated from megalopae obtained in neuston samples at Ubatuba, São Paulo, Brazil. The individuals were raised in the laboratory under constant temperature (25 ± 1°C), filtered sea water from the collection location (35‰), and natural photoperiod. Newly hatched Artemia sp.

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The first zoeal stages of ?Cataleptodius parvulus and Xanthodius denticulatus are described and compared with zoeae of other members of the subfamily Xanthinae. The larvae of ?C. parvulus and X.

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We investigated the relationships between common polymorphisms in CYP1A2 (CYP1A2(⁎)1C and (⁎)1F), CYP1A2-mRNA levels in circulating lymphocytes and clozapine(CLZ)-induced adverse drug reactions (ADRs) in 34 patients. Patients with ADRs had a higher frequency of CYP1A2 low activity allele combinations (8/12; 67%) and lower CYP1A2-mRNA levels than patients without ADRs (6/22; 27%, P=0.019).

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Objectives: The aim of this study was to compare bond failure and breakage rates of two types of bonded lingual orthodontic retainers (GFR and .0175" multistranded stainless steel wire [MST]) after a 6-year retention period.

Subjects And Methods: Eighty-five young adults were randomly divided into two groups: 40 subjects received 48 GFR retainers (14 maxillary and 34 mandibular retainers), and 45 subjects received 50 MST retainers (18 maxillary and 32 mandibular retainers).

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Background: Many studies indicate that migrants in western countries have limited access to and low utilization of community mental health centres (CMHCs) despite the high prevalence of mental disorders.

Aims: We aimed to compare migrant pathways to care across four CMHCs located in different Italian provinces and to identify pathway to care predictors.

Methods: Migrants attending the four CMHCs between 1 July 1999 and 31 December 2007 were included in the study.

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The aim of this study was to identify buccal/gingival cosmetic dentistry patterns subjacent to formation and professional practice of the dental surgeon from the ethnocentrism point of view. This is an exploratory study with a qualitative approach based on the thematic analysis. Initially a documental analysis was carried out.

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Many cases of coeliac disease, a gastrointestinal autoimmune disorder caused by sensitivity to gluten, can remain in a subclinical stage or undiagnosed. In a significant proportion of cases (10-15%) gluten intolerance can be associated with central or peripheral nervous system and psychiatric disorders.A 38-year-old man was admitted as to our department an inpatient for worsening anxiety symptoms and behavioural alterations.

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