Publications by authors named "Boli Wan"

Article Synopsis
  • Renovascular hypertension (RH) is a type of secondary hypertension that can harm heart health, increasing the risk of cardiovascular diseases.
  • The study explores the effects of Coniferol (CA), known for its ability to relax blood vessels, on RH-related heart conditions using a specific mouse model and heart cell line.
  • Results show CA lowers blood pressure and heart inflammation, targeting specific inflammatory pathways, making it a potential therapy for RH-induced heart issues.
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Article Synopsis
  • - Microplastics (MPs) are common in land ecosystems, but their effects on carbon and nitrogen cycles in plant-soil systems are not fully understood; a study analyzed data from 3338 paired observations across 180 publications for insights.
  • - Results indicated that MPs increased carbon emissions (CO) by 25.7% and boosted soil carbon content and microbial biomass, enhancing the soil's carbon capture ability.
  • - Despite increasing soil carbon storage, MPs decreased plant growth (aboveground biomass) and nitrogen loss while varying impacts were noted based on MP characteristics and soil properties, raising concerns for agricultural productivity.
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Ninjurin 1 (NINJ1) is a double-transmembrane cell-surface protein that might mediate plasma membrane rupture (PMR) and the diffusion of inflammatory factors. PMR is a characteristic of acinar cell injury in severe acute pancreatitis (SAP). However, the involvement of NINJ1 in mediating the PMR of acinar cells in SAP is currently unclear.

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Disseminated intravascular coagulation (DIC), which is closely related to platelet activation, is a key factor leading to high mortality in sepsis. The release of contents from plasma membrane rupture after platelet death further aggravates thrombosis. Nerve injury-induced protein 1 (NINJ1) is a cell membrane protein that mediates membrane disruption, a typical marker of cell death, through oligomerization.

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