An Investigation of Severe Influenza Cases in Russia during the 2022-2023 Epidemic Season and an Analysis of HA-D222G/N Polymorphism in Newly Emerged and Dominant Clade 6B.1A.5a.2a A(H1N1)pdm09 Viruses.

In Russia, during the COVID-19 pandemic, a decrease in influenza circulation was initially observed. Influenza circulation re-emerged with the dominance of new clades of A(H3N2) viruses in 2021-2022 and A(H1N1)pdm09 viruses in 2022-2023. In this study, we aimed to characterize influenza viruses during the 2022-2023 season in Russia, as well as investigate A(H1N1)pdm09 HA-D222G/N polymorphism associated with increased disease severity.

Manganese Oxide Nanoparticles Inhibit the Growth of Subcutaneous U-87MG Glioblastoma Xenografts in Immunodeficient Mouse.

Our previous study demonstrated that manganese oxide nanoparticles (MnO NP) selectively destroyed U-87MG and U251 human glioblastoma cells in vitro. MnO NP were synthesized and studied by electron microscopy. Their antitumor properties were studied in vivo on the model of immunodeficient SCID mice with subcutaneous xenografts of U-87MG human glioblastoma.

Phase states, microstructure and dielectric characteristics of solid solutions (1 - )NaNbO - CaNbO and (1 - )NaNbO - SrNbO.

Ceramics of binary systems solid solutions (1 - )NaNbO - CaNbO and (1 - )NaNbO - SrNbO with non-isostructural extreme components were prepared by the solid-phase reactions technique with the following sintering using conventional ceramic technology. It was found that ceramics with ≤ 0.2 have a perovskite structure.

[The possibility of using a laser stereolithography method in forensic medicine].

The data of computer-aided tomography are proposed to be used in forensic medical diagnostic and identification studies. The technology of making hard copies of objects by laser stereolithography on the basis of tomography data is described.

[The use of a modelling method in craniometry].

Laser interferometry is proposed for accurate measurements of the external parameters and fixation of the relief of human skull surface. This method creates a detailed three-dimensional computer model of the object of investigation, which can be used in automated systems of personality identification based on investigation of the skull and life-time photos. Further development of the method opens new vistas in automation of the trassological and ballistic identification.

[Caused of intensified lipid peroxidation in the blood of patients with viral hepatitis B].

The tissue oxygen concentration, the serum antioxidant system state and the serum malondialdehyde (MDA) concentration were studied in patients with hepatitis B. The good correlations were studied in patients with hepatitis B. The good correlations between MDA concentration in patients serum and the oxygen concentration in tissues (R-0.

[A two-dimensional map of proteins from left ventricle of the human heart].

A two-dimensional map of human heart left ventricular proteins for 213 polypeptide fractions has been constructed. A quantitative analysis of variability of the fraction position at 60 selected spots with the use of a CVIT computer system revealed a high reproducibility of the material distribution on electrophoregrams. Differences were found in the protein composition of eight heart muscle atrial and ventricular polypeptide fractions.

[The immunopathological mechanisms of the skin lesion in erysipelas patients].

The localization of bound IgG, IgA, IgM and component C3 of the complement in the focus of skin lesion in patients with different forms of erysipelas has been studied by the method of direct immunofluorescence. The presence of fixed immune complexes and component C3 in the affected areas of the skin at the acute period of the disease and their absence in the healthy areas of the skin have been established, which seems to be indicative of the presence of the local immunocomplex process in erysipelas. This process is one of the mechanisms of erysipelatous inflammation.