Corticosterone Induces Rapid Increase in the Amplitude of Inhibitory Response in Hippocampal Synapses with Asynchronous GABA Release.

Experiments were performed on cultured slices of rat ventral hippocampus. Using extracellular stimulation and patch clamp recording from pyramidal neurons in the hippocampal CA1 area, we studied characteristics of GABAergic synapse formed on these neurons by cholecystokinin-expressing interneurons. This synapse was characterized by asynchronous release of GABA and depolarization-induced suppression of inhibitory response.

Transfection of nerve cells.

Transfection is a method of transforming cells based on the introduction into living cells of plasmids encoding a particular protein or RNA. This review describes the main methods of transfection and considers their advantages and disadvantages. Most attention is paid to lentivirus transduction as one of the most efficient methods for transforming nerve cells.

[Transfection of the nervous system cells].

A review. Transfection is a method of cell transformation based on the introduction of a plasmid encoding a protein or RNA into the living cells. Basic methods of transfection and their strengths and weaknesses are discussed.

[Problems and prospects of physicians' training in "medical prophylaxis" specialty].

According to a Concept of continuous special education, postgraduate special training remains an essential link in creating a widely educated doctor with humanistic and natural-science ideology, high culture and knowledge of contemporary circumstances.

Impact of low-temperature plasmas on Deinococcus radiodurans and biomolecules.

The effects of cold plasma on Deinococcus radiodurans, plasmid DNA, and model proteins were assessed using microbiological, spectrometric, and biochemical techniques. In low power O(2) plasma (approximately 25 W, approximately 45 mTorr, 90 min), D. radiodurans, a radiation-resistant bacterium, showed a 99.

[Dependence of nutritive value of canned meat on the thermal of the raw materials and electric stimulation].

Research of influence electric stimulation and different thermal condition of raw material on meat protein breaking down by proteinases of gastrointestinal tract (pepsin, trypsin and chymotrypsin) was carried out. It was shown that electric stimulation increased the rate of meat protein proteolysis significantly, i.e.

[The cardiac activity in patients with liver cirrhosis based on the data from 24-hour ECG monitoring].

24-h ECG monitoring was performed in healthy subjects and patients with hepatic cirrhosis. Abnormalities rare in healthy individuals and frequent in the patients were registered. Cirrhosis patients presented marked changes in time parameters of cardiac performance.

[Thermal inactivation kinetics of cathepsin D from porcine muscle tissue in the presence of sodium chloride].

The effect of incubation temperature on the activity of cathepsin D from pig muscles was studied at different pH values. The highest activity of cathepsin D was observed at pH 3.0 and 37 degrees C.

[Structure of mental pathology among various adolescent population groups (clinico-epidemiological study)].

The authors have examined 1455 adolescents aged 15-17 yrs, those followed up at a psychiatric outpatient clinic and from the general population. The study has revealed the distribution of different forms of mental diseases and their syndromal structure. The authors stress the polymorphism of psychopathological appearances and describe some features of mental disturbances in adolescents.

[Diagnosis and the treatment procedure in wounds of the heart and pericardium].

An analysis of 136 clinical observations has shown that clinical symptoms and additional methods of examination (X-ray analysis of the chest, ECG, puncture of the pleura and pericardium) are sufficient for timely diagnosis of wounds of the heart and pericardium. The necessity of urgent operation prevents using complex diagnostic methods. Outcomes of the treatment are dependent on the time of admission of the patient to the hospital and timely operative interventions.