Role of protein kinase C- or RhoA-induced Ca(2+) sensitization in stretch-induced myogenic tone.

Objective: It has been suggested that Ca(2+) sensitization mechanisms might contribute to myogenic tone. However, specific mechanisms have yet to be fully identified. Therefore, we investigated the role of protein kinase C (PKC)- or RhoA-induced Ca(2+) sensitization in myogenic tone of the rabbit basilar vessel.