Radiocarbon dataset for the TRB central-place at Kałdus, Poland.

This dataset compiles radiocarbon dates received for botanical macroremains and animal bones from domestic and ritual pits and human graves unearthed during excavations at the archaeological site of Kałdus (Poland) that can be related to the Funnel Beaker culture (TRB). Prior to radiocarbon dating by accelerator mass spectrometry (AMS), plant macroremains were checked against diagnostic attributes of species identification by standard paleobotanical analysis. The dataset contains already published ( = 4) and new ( = 10) radiocarbon dates that were used to establish the absolute chronology of the TRB habitus at Kałdus and its diachronic spatial organization.

Parrots in the wild in Polish cities.

Amateur breeding of parrots as pets has contributed to many species being found in areas where they never occurred in the wild, particularly in warmer regions, but also in the temperate climates of North America and Europe. Climate change is likely to exacerbate this process. We hypothesised that parrots occurred in the wild in the cities of Poland, especially the rose-ringed parakeet, as there are reports of breeding sites in the literature.

Long Arm of Motorway-The Impact of Fenced Road on the Mortality of European Badgers.

We studied the impact of the new fenced and accident-safe motorway on the mortality of European badgers Meles meles on local roads in western Poland in 2010-2015. We monitored the badgers mortality on local roads of three categories: main roads, secondary roads and county roads. The study was conducted before and after the opening of the motorway in 2012.

Does the radiation approach affect acute toxicity in prostate cancer patients? A comparison of four radiation techniques.

Introduction: Prostate cancer is treated with increasingly sophisticated radiation techniques. The aim of the study is to compare acute toxicity in patients managed with different therapeutic modalities.

Material And Methods: A total of 60 patients irradiated between 2012 and 2016 were analyzed: A.

Analysis of maternal lineage structure of individuals from chamber graves placed in medieval cemetery in Kałdus, Central Poland.

The beginning of the early Middle Ages period in Poland (10-14 century) has been widely debated in the context of an active demographic inflow from other countries and its contribution to the creation of the new country. Finding chamber graves which are considered typical for the Scandinavian ethnic group in a few cemeteries in Poland has become the basis for the anthropological inference on the potential participation of North European people in forming the social elite of medieval Poland. However, the question of whether this fact was the result of presence of people from other countries lacks an unambiguous answer.

Frequent or scarce? Damage to flight-enabling body parts in bats (Chiroptera).

Bat wings are characterized by high endurance, and these mammals have developed a number of adaptations that protect them from falling into obstacles and potential injuries. However, in bat populations, there are individuals with visible fresh or healed injuries to the flight-enabling body parts. The aim of this research was to determine the differences in the occurrence of wing membrane damages among species of bats that differ in ecology and behavior.

Analysis of medieval mtDNA from Napole cemetery provides new insights into the early history of Polish state.

Contemporary historical anthropology and classical archaeology are concerned not only with such fundamental issues as the origins of ancient human populations and migration routes, but also with the formation and development of inter-population relations and the mixing of gene pools as a result of inter-breeding between individuals representing different cultural units. The contribution of immigrants to the analysed autochthonous population and their effect on the gene pool of that population has proven difficult to evaluate with classical morphological methods. The burial of one individual in the studied Napole cemetery located in central Poland had the form of a chamber grave, which is typical of Scandinavian culture from that period.

Damped sinusoidal function to model acute irradiation in radiotherapy patients.

In the paper, we suggest a damped sinusoidal function be used to model a regenerative response of mucosa in time after the radiotherapy treatment. The medical history of 389 RT patients irradiated within the years 1994-2000 at the Radiotherapy Department, Cancer Center, Maria Skłodowska-Curie Memorial Institute of Oncology, Gliwice, Poland, was taken into account. In the analyzed group of patients, the number of observations of a single patient ranged from 2 to 25 (mean = 8.

Sexual dimorphism in Hucul horses using discriminant analysis.

The purpose of this study has been to evaluate the applicability of discriminant function analysis to determine gender dimorphism in Hucul horses, based on morphological indices obtained in different stages of life. A total of 243 horses, divided into six age groups, have been examined in its course. For each horse we have measured 12 metric traits, which were then used to calculate 13 biometric indices commonly used in horse breeding in Poland.

Hydrolysis of 2,4-dithiophenobarbital.

Hydrolysis of 2,4-dithiophenobarbital in aqueous solutions of pH 2-12 was investigated at 40 and 60 degrees C using UV spectrophotometry. The values of reaction order, rate constants, pKa1 and pKa2 and activation energy were determined. The preliminary estimation of degradation products was accomplished using thin layer chromatography.

Lipophilicity of thiobarbiturates determined by TLC.

Lipophilicty of 29 thiobarbituric acid derivatives were assessed by reversed-phase thin-layer chromatography using methanol: water mixtures as a mobile phase. A linear relationship was found between RM values and methanol concentrations in the mobile phase. The retention parameter, RM0, was related to theoretical partition coefficients calculated by means of different theoretical procedures (AlogPs, IAlogP, miLogP, logPKowwin, xlogP).

Stability of 2-thiophenobarbital and its N-methyl derivatives in the presence of beta-cyclodextrin.

The rates of hydrolysis of thiophenobarbital and its N-mono- and N,N'-dimethyl-derivatives were determined under different conditions of pH and temperature using UV spectroscopy. They were compared with those obtained in the presence of different concentrations of beta-cyclodextrin. It was found that the compounds degrade with different rates and beta-cyclodextrin retards the hydrolysis.

CT imaging findings of pulmonary neoplasms after treatment with radiofrequency ablation: results in 32 tumors.

Objective: The purpose of this study is to describe the CT appearance of thoracic neoplasms after treatment with radiofrequency ablation (RFA).

Materials And Methods: Thirty-two thoracic neoplasms in 26 patients had pulmonary RFA and imaging follow-up. Fourteen neoplasms were primary lung cancer and 18 were metastases.

Gamma-hydrobutyric acid (GHB) and its chemical modifications: a review of the GHBergic system.

Gamma-hydroxybutyric acid (GHB) is a naturally occurring substance with function of an inhibitory neurotransmitter in the central nervous system in mammals. GHB can be used as a medicine in narcolepsy (Xyrem) and for general anesthesia (sodium oxybate). It is also a popular drug of abuse, causing coma, addiction and severe withdrawal syndrome, and, therefore, demanding thorough studies on the GHBergic system and expanded research on toxicology of this compound.

Hydrolysis of N,N- and N,S-dimethyl derivatives of 2-thiophenobarbital.

Kinetics of hydrolysis of N,N- and N,S-dimethyl-2-thiophenobarbital and products of this reaction were investigated. The UV spectroscopy served as a tool for kinetic investigations and chromatography was used to separate and isolate the main products of hydrolysis. These products were identified by spectroscopic methods and the course of hydrolysis of both isomers was compared.

Hydrolysis of N- and S-monomethyl derivatives of 2-thiophenobarbital.

Kinetics of hydrolysis of S-methyl-2-thiophenobarbital in aqueous solutions was investigated using the UV spectroscopic method within the pH range 1.5-12.9 at 60 degrees C.

Stereoselective chromatography of cardiovascular drugs: an update.

This review reports the latest achievements in chromatographic enantioseparations of various classes of cardiovascular drugs and selected applications of these methods in pharmaceutical and clinical analysis. The use of these drugs as test compounds for new chiral stationary phases and different parameters of chromatographic processes is also presented.

Recent applications of stereoselective chromatography.

Some recent applications of stereoselective chromatography in the fields of clinical pharmacy, drug analysis, food, and natural products are reviewed. The review is documented with up-to-date literature, which will assist further expansion of research in these areas.

Enantioseparation of chiral thiobarbiturates using cyclodextrin-modified capillary electrophoresis.

The racemates of several chiral thiobarbiturates were separated by using different cyclodextrins in capillary electrophoresis (CE). Six neutral and negatively charged cyclodextrins 1 (CDs) were employed as chiral separators whereof five led to successful separation of enantiomeric thiobarbiturate pairs. The CDs used were the native alpha-CD, beta-CD, gamma-CD, and heptakis-(2,6-di-O-methyl)-beta-cyclodextrin (HDM) as well as heptakis-(2,3-di-O-methyl-6-sulfato)-beta-cyclodextrin (HDMS) and heptakis-(2,3-di-O-acetyl-6-sulfato)-beta-CD (HDAS).

Retention of barbituric acid derivatives on immobilized artificial membrane stationary phase and its correlation with biological activity.

A series of 30 barbituric acid derivatives were subjected to high-performance liquid chromatography (HPLC) on the 'immobilized artificial membrane' (IAM) column with acetonitrile buffer mobile phase. The retention parameter log k(IAM) was related to the logarithms of partition coefficients determined in octanol-water partition system, log P, to a thin-layer chromatographic (TLC) parameter from partition TLC, R(m0), to an adsorption HPLC retention parameter, log k(0), and to a solubility parameter, delta. It was demonstrated that log k(IAM) correlated significantly to the other parameters of barbiturates determined in partition systems but not to delta.

The impact of chirality of the fluorinated volatile inhalation anaesthetics on their clinical applications.

This review discusses the various chromatographic enantioseparation methods on an analytical and preparative scale for fluorinated inhalation anaesthetics used clinically, namely halothane, enflurane, desflurane and isoflurane. The differences in the pharmacodynamics and pharmacokinetics between the enantiomers of those anaesthetics are presented. It can be concluded that using a single enantiomer for these fluorinated anaesthetics is advantageous over using the racemic mixture.

Recent chromatographic and electrophoretic enantioseparations of cardiovascular drugs.

The chromatographic and electrophoretic enantiomeric separation and analysis of several clinically used cardiovascular drugs have been reviewed. Several examples of recently reported applications of enantioselective analysis and various cardiovascular agents are presented.

Enantioselective high performance liquid chromatographic assay of acebutolol and its active metabolite diacetolol in human serum.

A stereoselective direct liquid chromatographic method for assay of the enantiomers of the beta-adrenergic blocker acebutolol (AC) and its active metabolite, diacetolol (DC), in human serum was developed. The assay is based on extraction with ethyl acetate and separation of enantiomers on an amylose tris-(3,5-dimethylphenylcarbamate) chiral stationary phase (Chiralpak AD) column. The method was validated and proved useful for the determination of the enantiomers in serum samples of patients suffering from hypertension and chronically treated with racemic AC.

Recent applications of chromatographic resolution of enantiomers in pharmaceutical analysis.

The principles and applications of chromatographic separation of enantiomers in pharmaceutical analysis have been reviewed. Several of recently reported enantioselective analysis of various racemic drugs using both the 'indirect' and 'direct' methods have been presented.