Publications by authors named "Bojana Banovic Djeri"
The pervasive role of alternative promoters in context-specific isoform expression and the importance of promoter choice over its level of transcriptional activity have been recently implied based on pan-cancer studies. We aimed to explore this phenomenon at the cellular level on the example of a major tumor suppressor SMAD4 in search of molecular mechanisms in colorectal cancer that could be exploited for novel biomarkers or therapeutic approaches. Multi-omics technologies, tools and functional assays were applied to analyze the transcripts expression and the alternative promoters' function of the SMAD4 gene in colon cell lines HCEC-1CT, HCT116, DLD-1, SW480 and SW620.
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- - The study monitored the evolution and emergence of SARS-CoV-2 variants in Serbia between March 2020 and January 2023, analyzing samples from 2,398 COVID-19-positive patients using advanced sequencing technologies.
- - Three major variants of concern were identified: Alpha (5.6%), Delta (7.4%), and Omicron (70.3%), with the Omicron recombinant known as "Kraken" (<1%), along with other sublineages contributing to eight pandemic waves in Serbia similar to trends observed in Europe and the U.S.
- - The research revealed a variety of mutations in the virus, particularly in the spike protein, with a total of sixteen Nextstrain clades being assigned to the samples
Bacterial Nanocellulose as a Scaffold for Cell Migration Assay.
Nanomaterials (Basel)
September 2021
Bacterial nanocellulose (BNC) stands out among polymers as a promising biomaterial due to its mechanical strength, hydrophilicity, biocompatibility, biodegradability, low toxicity and renewability. The use of scaffolds based on BNC for 3D cell culture has been previously demonstrated. The study exploited excellent properties of the BNC to develop an efficient and low-cost in vitro cell migration assay.
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